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Cytokeratin alteration in oral leukoplakia and oral squamous cell carcinoma.

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Cytokeratin alteration in oral leukoplakia and oral squamous cell carcinoma. / Fillies, Thomas; Jogschies, Mirco; Kleinheinz, Johannes; Brandt, Burkhard; Joos, Ulrich; Buerger, Horst.

In: ONCOL REP, Vol. 18, No. 3, 3, 2007, p. 639-643.

Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

Harvard

Fillies, T, Jogschies, M, Kleinheinz, J, Brandt, B, Joos, U & Buerger, H 2007, 'Cytokeratin alteration in oral leukoplakia and oral squamous cell carcinoma.', ONCOL REP, vol. 18, no. 3, 3, pp. 639-643. <http://www.ncbi.nlm.nih.gov/pubmed/17671713?dopt=Citation>

APA

Fillies, T., Jogschies, M., Kleinheinz, J., Brandt, B., Joos, U., & Buerger, H. (2007). Cytokeratin alteration in oral leukoplakia and oral squamous cell carcinoma. ONCOL REP, 18(3), 639-643. [3]. http://www.ncbi.nlm.nih.gov/pubmed/17671713?dopt=Citation

Vancouver

Fillies T, Jogschies M, Kleinheinz J, Brandt B, Joos U, Buerger H. Cytokeratin alteration in oral leukoplakia and oral squamous cell carcinoma. ONCOL REP. 2007;18(3):639-643. 3.

Bibtex

@article{56294b0217f5486eb7e9455d9c1f2cb6,
title = "Cytokeratin alteration in oral leukoplakia and oral squamous cell carcinoma.",
abstract = "Intermediate filaments are involved in cell migration and intracellular signal transduction pathways. In a variety of organs, the expression of distinct intermediary filaments are further associated with distinct steps of malignant transformation. In this study, we seeked to define the cytokeratin (Ck) expression pattern in oral leukoplakia and oral squamous cell carcinoma (OSCC). One hundred and ninety-two patients with OSCC, 117 patients with oral leukoplakia without dysplasia (OL) and 23 with oral leukoplakia with dysplasia (squamous intraepithelial neoplasia) (OLD) of the oral cavity were investigated for the immunohistochemical expression of Ck 5-6, Ck 8/18, Ck 1 Ck 10, Ck 14, Ck 19 using the tissue microarray technique. Correlations between clinical features and the expression of cytokeratins were evaluated statistically by chi2 tests. The expression of Ck 8/18, Ck 19 and Ck 1 was seen in 3.1% (Ck 8/18), 12.5% (Ck 19), 75.4% (Ck 1) of all leukoplakias, 1.0% (Ck 8/18), 9.4% (Ck 19), 76.8% (Ck 1) in OL, 13.0% (Ck 8/18), 27.3% (Ck 19), 68.4% (Ck 1) in OLD and was significantly associated with the degree of dysplasia (Ck 8/18 p",
author = "Thomas Fillies and Mirco Jogschies and Johannes Kleinheinz and Burkhard Brandt and Ulrich Joos and Horst Buerger",
year = "2007",
language = "Deutsch",
volume = "18",
pages = "639--643",
journal = "ONCOL REP",
issn = "1021-335X",
publisher = "Spandidos Publications",
number = "3",

}

RIS

TY - JOUR

T1 - Cytokeratin alteration in oral leukoplakia and oral squamous cell carcinoma.

AU - Fillies, Thomas

AU - Jogschies, Mirco

AU - Kleinheinz, Johannes

AU - Brandt, Burkhard

AU - Joos, Ulrich

AU - Buerger, Horst

PY - 2007

Y1 - 2007

N2 - Intermediate filaments are involved in cell migration and intracellular signal transduction pathways. In a variety of organs, the expression of distinct intermediary filaments are further associated with distinct steps of malignant transformation. In this study, we seeked to define the cytokeratin (Ck) expression pattern in oral leukoplakia and oral squamous cell carcinoma (OSCC). One hundred and ninety-two patients with OSCC, 117 patients with oral leukoplakia without dysplasia (OL) and 23 with oral leukoplakia with dysplasia (squamous intraepithelial neoplasia) (OLD) of the oral cavity were investigated for the immunohistochemical expression of Ck 5-6, Ck 8/18, Ck 1 Ck 10, Ck 14, Ck 19 using the tissue microarray technique. Correlations between clinical features and the expression of cytokeratins were evaluated statistically by chi2 tests. The expression of Ck 8/18, Ck 19 and Ck 1 was seen in 3.1% (Ck 8/18), 12.5% (Ck 19), 75.4% (Ck 1) of all leukoplakias, 1.0% (Ck 8/18), 9.4% (Ck 19), 76.8% (Ck 1) in OL, 13.0% (Ck 8/18), 27.3% (Ck 19), 68.4% (Ck 1) in OLD and was significantly associated with the degree of dysplasia (Ck 8/18 p

AB - Intermediate filaments are involved in cell migration and intracellular signal transduction pathways. In a variety of organs, the expression of distinct intermediary filaments are further associated with distinct steps of malignant transformation. In this study, we seeked to define the cytokeratin (Ck) expression pattern in oral leukoplakia and oral squamous cell carcinoma (OSCC). One hundred and ninety-two patients with OSCC, 117 patients with oral leukoplakia without dysplasia (OL) and 23 with oral leukoplakia with dysplasia (squamous intraepithelial neoplasia) (OLD) of the oral cavity were investigated for the immunohistochemical expression of Ck 5-6, Ck 8/18, Ck 1 Ck 10, Ck 14, Ck 19 using the tissue microarray technique. Correlations between clinical features and the expression of cytokeratins were evaluated statistically by chi2 tests. The expression of Ck 8/18, Ck 19 and Ck 1 was seen in 3.1% (Ck 8/18), 12.5% (Ck 19), 75.4% (Ck 1) of all leukoplakias, 1.0% (Ck 8/18), 9.4% (Ck 19), 76.8% (Ck 1) in OL, 13.0% (Ck 8/18), 27.3% (Ck 19), 68.4% (Ck 1) in OLD and was significantly associated with the degree of dysplasia (Ck 8/18 p

M3 - SCORING: Zeitschriftenaufsatz

VL - 18

SP - 639

EP - 643

JO - ONCOL REP

JF - ONCOL REP

SN - 1021-335X

IS - 3

M1 - 3

ER -