Cycling multisensory changes in migraine: more than a headache

TY - JOUR

T1 - Cycling multisensory changes in migraine: more than a headache

AU - Peng, Kuan-Po

AU - May, Arne

AU - Basedau, Hauke

N1 - Copyright © 2022 Wolters Kluwer Health, Inc. All rights reserved.

PY - 2022/6/1

Y1 - 2022/6/1

N2 - PURPOSE OF REVIEW: Research on migraine usually focuses on the headache; however, accumulating evidence suggests that migraine not only changes the somatosensory system for nociception (pain), but also the other modalities of perception, such as visual, auditory or tactile sense. More importantly, the multisensory changes exist beyond the headache (ictal) phase of migraine and show cyclic changes, suggesting a central generator driving the multiple sensory changes across different migraine phases. This review summarizes the latest studies that explored the cyclic sensory changes of migraine.RECENT FINDINGS: Considerable evidence from recent neurophysiological and functional imaging studies suggests that alterations in brain activation start at least 48 h before the migraine headache and outlast the pain itself for 24 h. Several sensory modalities are involved with cyclic changes in sensitivity that peak during the ictal phase.SUMMARY: In many ways, migraine represents more than just vascular-mediated headaches. Migraine alters the propagation of sensory information long before the headache attack starts.

AB - PURPOSE OF REVIEW: Research on migraine usually focuses on the headache; however, accumulating evidence suggests that migraine not only changes the somatosensory system for nociception (pain), but also the other modalities of perception, such as visual, auditory or tactile sense. More importantly, the multisensory changes exist beyond the headache (ictal) phase of migraine and show cyclic changes, suggesting a central generator driving the multiple sensory changes across different migraine phases. This review summarizes the latest studies that explored the cyclic sensory changes of migraine.RECENT FINDINGS: Considerable evidence from recent neurophysiological and functional imaging studies suggests that alterations in brain activation start at least 48 h before the migraine headache and outlast the pain itself for 24 h. Several sensory modalities are involved with cyclic changes in sensitivity that peak during the ictal phase.SUMMARY: In many ways, migraine represents more than just vascular-mediated headaches. Migraine alters the propagation of sensory information long before the headache attack starts.

KW - Brain/diagnostic imaging

KW - Headache

KW - Humans

KW - Migraine Disorders/complications

U2 - 10.1097/WCO.0000000000001059

DO - 10.1097/WCO.0000000000001059

M3 - SCORING: Review article

C2 - 35674081

VL - 35

SP - 367

EP - 372

JO - CURR OPIN NEUROL

JF - CURR OPIN NEUROL

SN - 1350-7540

IS - 3

ER -