Current practice and evolving concepts in septic shock resuscitation
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Current practice and evolving concepts in septic shock resuscitation. / Bakker, Jan; Kattan, Eduardo; Annane, Djillali; Castro, Ricardo; Cecconi, Maurizio; de Backer, Daniel; Dubin, Arnaldo; Evans, Laura; Gong, Michelle Ng; Hamzaoui, Olfa; Ince, Can; Levy, Bruno; Monnet, Xavier; Tascón, Gustavo A Ospina; Ostermann, Marlies; Pinsky, Michal R; Russell, James A; Saugel, Bernd; Scheeren, Thomas W L; Teboul, Jean-Louis; Baron, Antoine Vieillard; Vincent, Jean-Louis; Zampieri, Fernando G; Hernandez, Glenn.
In: INTENS CARE MED, Vol. 48, No. 2, 02.2022, p. 148-163.Research output: SCORING: Contribution to journal › SCORING: Review article › Research
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TY - JOUR
T1 - Current practice and evolving concepts in septic shock resuscitation
AU - Bakker, Jan
AU - Kattan, Eduardo
AU - Annane, Djillali
AU - Castro, Ricardo
AU - Cecconi, Maurizio
AU - de Backer, Daniel
AU - Dubin, Arnaldo
AU - Evans, Laura
AU - Gong, Michelle Ng
AU - Hamzaoui, Olfa
AU - Ince, Can
AU - Levy, Bruno
AU - Monnet, Xavier
AU - Tascón, Gustavo A Ospina
AU - Ostermann, Marlies
AU - Pinsky, Michal R
AU - Russell, James A
AU - Saugel, Bernd
AU - Scheeren, Thomas W L
AU - Teboul, Jean-Louis
AU - Baron, Antoine Vieillard
AU - Vincent, Jean-Louis
AU - Zampieri, Fernando G
AU - Hernandez, Glenn
N1 - © 2021. Springer-Verlag GmbH Germany, part of Springer Nature.
PY - 2022/2
Y1 - 2022/2
N2 - Clinical and pathophysiological understanding of septic shock has progressed exponentially in the previous decades, translating into a steady decrease in septic shock-related morbidity and mortality. Even though large randomized, controlled trials have addressed fundamental aspects of septic shock resuscitation, many questions still exist. In this review, we will describe the current standards of septic shock resuscitation, but the emphasis will be placed on evolving concepts in different domains such as clinical resuscitation targets, adequate use of fluids and vasoactive drugs, refractory shock, and the use of extracorporeal therapies. Multiple research opportunities remain open, and collaborative endeavors should be performed to fill in these gaps.
AB - Clinical and pathophysiological understanding of septic shock has progressed exponentially in the previous decades, translating into a steady decrease in septic shock-related morbidity and mortality. Even though large randomized, controlled trials have addressed fundamental aspects of septic shock resuscitation, many questions still exist. In this review, we will describe the current standards of septic shock resuscitation, but the emphasis will be placed on evolving concepts in different domains such as clinical resuscitation targets, adequate use of fluids and vasoactive drugs, refractory shock, and the use of extracorporeal therapies. Multiple research opportunities remain open, and collaborative endeavors should be performed to fill in these gaps.
U2 - 10.1007/s00134-021-06595-9
DO - 10.1007/s00134-021-06595-9
M3 - SCORING: Review article
C2 - 34910228
VL - 48
SP - 148
EP - 163
JO - INTENS CARE MED
JF - INTENS CARE MED
SN - 0342-4642
IS - 2
ER -