CT angiography in the setting of suspected acute mesenteric ischemia: prevalence of ischemic and alternative diagnoses

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CT angiography in the setting of suspected acute mesenteric ischemia: prevalence of ischemic and alternative diagnoses. / Henes, Frank Oliver; Pickhardt, Perry J; Herzyk, Andrzej; Lee, Scott J; Motosugi, Utaroh; Derlin, Thorsten; Lubner, Meghan G; Adam, Gerhard; Schön, Gerhard; Bannas, Peter.

In: ABDOM RADIOL, Vol. 42, No. 4, 04.2017, p. 1152-1161.

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@article{4cfb92296c34458483b0640ff3841a28,
title = "CT angiography in the setting of suspected acute mesenteric ischemia: prevalence of ischemic and alternative diagnoses",
abstract = "PURPOSE: The purpose of the study was to determine the prevalence of ischemic and alternative diagnoses and the diagnostic accuracy of CT angiography (CTA) in the setting of suspected acute mesenteric ischemia (AMI).MATERIAL AND METHODS: We included 959 patients undergoing CTA for the evaluation of suspected AMI. The final clinical diagnosis was used to determine the prevalence of ischemic and alternative diagnoses and to calculate the diagnostic accuracy of CTA. Prevalence of diagnoses by age, sex, and admission status was compared using Cochran-Armitage and χ (2) tests.RESULTS: Prevalence was 18.8% (180/959) for AMI and 61.2% (587/959) for specific alternative diagnoses. In the remaining 20.0% (192/959), no clear clinical diagnosis was established. The most frequent alternative diagnoses were small-bowel obstruction (10.4%; 61/587), infectious colitis (8.7%; 51/587), pneumonia (6.5%; 38/587), cholecystitis (6.1%; 36/587), and diverticulitis (5.6%; 33/587). Prevalence of specific alternative diagnoses varied significantly according to both age (p < .013) and admissions status (p < 0.001). CTA had a sensitivity and specificity for diagnosing AMI of 89.4%/99.5% and for alternative diagnoses of 86.7%/96.9%, respectively.CONCLUSION: In the setting of suspected AMI, the prevalence of ischemic and alternative diagnoses varies significantly by age, sex, and admission status. CTA provides for rapid and non-invasive assessment of ischemic and alternative diagnoses with high diagnostic accuracy.",
author = "Henes, {Frank Oliver} and Pickhardt, {Perry J} and Andrzej Herzyk and Lee, {Scott J} and Utaroh Motosugi and Thorsten Derlin and Lubner, {Meghan G} and Gerhard Adam and Gerhard Sch{\"o}n and Peter Bannas",
year = "2017",
month = apr,
doi = "10.1007/s00261-016-0988-0",
language = "English",
volume = "42",
pages = "1152--1161",
journal = "ABDOM RADIOL",
issn = "2366-004X",
publisher = "Springer New York",
number = "4",

}

RIS

TY - JOUR

T1 - CT angiography in the setting of suspected acute mesenteric ischemia: prevalence of ischemic and alternative diagnoses

AU - Henes, Frank Oliver

AU - Pickhardt, Perry J

AU - Herzyk, Andrzej

AU - Lee, Scott J

AU - Motosugi, Utaroh

AU - Derlin, Thorsten

AU - Lubner, Meghan G

AU - Adam, Gerhard

AU - Schön, Gerhard

AU - Bannas, Peter

PY - 2017/4

Y1 - 2017/4

N2 - PURPOSE: The purpose of the study was to determine the prevalence of ischemic and alternative diagnoses and the diagnostic accuracy of CT angiography (CTA) in the setting of suspected acute mesenteric ischemia (AMI).MATERIAL AND METHODS: We included 959 patients undergoing CTA for the evaluation of suspected AMI. The final clinical diagnosis was used to determine the prevalence of ischemic and alternative diagnoses and to calculate the diagnostic accuracy of CTA. Prevalence of diagnoses by age, sex, and admission status was compared using Cochran-Armitage and χ (2) tests.RESULTS: Prevalence was 18.8% (180/959) for AMI and 61.2% (587/959) for specific alternative diagnoses. In the remaining 20.0% (192/959), no clear clinical diagnosis was established. The most frequent alternative diagnoses were small-bowel obstruction (10.4%; 61/587), infectious colitis (8.7%; 51/587), pneumonia (6.5%; 38/587), cholecystitis (6.1%; 36/587), and diverticulitis (5.6%; 33/587). Prevalence of specific alternative diagnoses varied significantly according to both age (p < .013) and admissions status (p < 0.001). CTA had a sensitivity and specificity for diagnosing AMI of 89.4%/99.5% and for alternative diagnoses of 86.7%/96.9%, respectively.CONCLUSION: In the setting of suspected AMI, the prevalence of ischemic and alternative diagnoses varies significantly by age, sex, and admission status. CTA provides for rapid and non-invasive assessment of ischemic and alternative diagnoses with high diagnostic accuracy.

AB - PURPOSE: The purpose of the study was to determine the prevalence of ischemic and alternative diagnoses and the diagnostic accuracy of CT angiography (CTA) in the setting of suspected acute mesenteric ischemia (AMI).MATERIAL AND METHODS: We included 959 patients undergoing CTA for the evaluation of suspected AMI. The final clinical diagnosis was used to determine the prevalence of ischemic and alternative diagnoses and to calculate the diagnostic accuracy of CTA. Prevalence of diagnoses by age, sex, and admission status was compared using Cochran-Armitage and χ (2) tests.RESULTS: Prevalence was 18.8% (180/959) for AMI and 61.2% (587/959) for specific alternative diagnoses. In the remaining 20.0% (192/959), no clear clinical diagnosis was established. The most frequent alternative diagnoses were small-bowel obstruction (10.4%; 61/587), infectious colitis (8.7%; 51/587), pneumonia (6.5%; 38/587), cholecystitis (6.1%; 36/587), and diverticulitis (5.6%; 33/587). Prevalence of specific alternative diagnoses varied significantly according to both age (p < .013) and admissions status (p < 0.001). CTA had a sensitivity and specificity for diagnosing AMI of 89.4%/99.5% and for alternative diagnoses of 86.7%/96.9%, respectively.CONCLUSION: In the setting of suspected AMI, the prevalence of ischemic and alternative diagnoses varies significantly by age, sex, and admission status. CTA provides for rapid and non-invasive assessment of ischemic and alternative diagnoses with high diagnostic accuracy.

U2 - 10.1007/s00261-016-0988-0

DO - 10.1007/s00261-016-0988-0

M3 - SCORING: Journal article

C2 - 27885390

VL - 42

SP - 1152

EP - 1161

JO - ABDOM RADIOL

JF - ABDOM RADIOL

SN - 2366-004X

IS - 4

ER -