Cross-Variant Neutralizing Serum Activity after SARS-CoV-2 Breakthrough Infections
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Cross-Variant Neutralizing Serum Activity after SARS-CoV-2 Breakthrough Infections. / Tober-Lau, Pinkus; Gruell, Henning; Vanshylla, Kanika; Koch, Willi M; Hillus, David; Schommers, Philipp; Suárez, Isabelle; Suttorp, Norbert; Sander, Leif Erik; Klein, Florian; Kurth, Florian.
In: EMERG INFECT DIS, Vol. 28, No. 5, 05.2022, p. 1050-1052.Research output: SCORING: Contribution to journal › Other (editorial matter etc.) › Research
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TY - JOUR
T1 - Cross-Variant Neutralizing Serum Activity after SARS-CoV-2 Breakthrough Infections
AU - Tober-Lau, Pinkus
AU - Gruell, Henning
AU - Vanshylla, Kanika
AU - Koch, Willi M
AU - Hillus, David
AU - Schommers, Philipp
AU - Suárez, Isabelle
AU - Suttorp, Norbert
AU - Sander, Leif Erik
AU - Klein, Florian
AU - Kurth, Florian
PY - 2022/5
Y1 - 2022/5
N2 - To determine neutralizing activity against the severe acute respiratory syndrome coronavirus 2 ancestral strain and 4 variants of concern, we tested serum from 30 persons with breakthrough infection after 2-dose vaccination. Cross-variant neutralizing activity was comparable to that after 3-dose vaccination. Shorter intervals between vaccination and breakthrough infection correlated with lower neutralizing titers.
AB - To determine neutralizing activity against the severe acute respiratory syndrome coronavirus 2 ancestral strain and 4 variants of concern, we tested serum from 30 persons with breakthrough infection after 2-dose vaccination. Cross-variant neutralizing activity was comparable to that after 3-dose vaccination. Shorter intervals between vaccination and breakthrough infection correlated with lower neutralizing titers.
KW - Antibodies, Neutralizing
KW - Antibodies, Viral
KW - COVID-19
KW - Humans
KW - SARS-CoV-2
KW - Vaccination
U2 - 10.3201/eid2805.220271
DO - 10.3201/eid2805.220271
M3 - Other (editorial matter etc.)
C2 - 35259088
VL - 28
SP - 1050
EP - 1052
JO - EMERG INFECT DIS
JF - EMERG INFECT DIS
SN - 1080-6040
IS - 5
ER -