Cross-European validation of the ItchyQoL in pruritic dermatoses
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Cross-European validation of the ItchyQoL in pruritic dermatoses. / Zeidler, C; Steinke, S; Riepe, C; Bruland, P; Soto-Rey, I; Storck, M; Garcovich, S; Blome, C; Bobko, S; Legat, F J; Potekaev, N; Lvov, A; Misery, L; Weger, W; Reich, A; Şavk, E; Streit, M; Serra-Baldrich, E; Szepietowski, J C; Yosipovitch, G; Chen, S C; Dugas, M; Ständer, S.
In: J EUR ACAD DERMATOL, Vol. 33, No. 2, 02.2019, p. 391-397.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
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TY - JOUR
T1 - Cross-European validation of the ItchyQoL in pruritic dermatoses
AU - Zeidler, C
AU - Steinke, S
AU - Riepe, C
AU - Bruland, P
AU - Soto-Rey, I
AU - Storck, M
AU - Garcovich, S
AU - Blome, C
AU - Bobko, S
AU - Legat, F J
AU - Potekaev, N
AU - Lvov, A
AU - Misery, L
AU - Weger, W
AU - Reich, A
AU - Şavk, E
AU - Streit, M
AU - Serra-Baldrich, E
AU - Szepietowski, J C
AU - Yosipovitch, G
AU - Chen, S C
AU - Dugas, M
AU - Ständer, S
N1 - © 2018 European Academy of Dermatology and Venereology.
PY - 2019/2
Y1 - 2019/2
N2 - BACKGROUND: Chronic pruritus (CP) is a frequently occurring symptom in inflammatory dermatoses, causing a high burden and limitations to health-related quality of life (HRQoL).OBJECTIVE: The ItchyQoL was developed to assess the impairment to HRQoL in patients with CP. However, it has only been validated in English and German. Here, we report the validation in several languages across Europe.METHODS: After professional translation, the versions of ItchyQoL were digitized for use as a tablet application. Validation was performed in clinics for dermatology in Austria, France, Germany, Italy, Poland, Russia, Spain, Switzerland and Turkey.RESULTS: Five hundred and thirty-five patients with either contact dermatitis, chronic prurigo - nodular type, psoriasis vulgaris, lichen planus or mycosis fungoides/Sézary syndrome and with CP ≥ 3 on the numerical rating scale were included. ItchyQoL showed a high level of consistency (Cronbach's-α, all: 0.95) and test-retest reliability (intraclass correlation: 0.91). It strongly correlated with the Dermatology Life Quality Index (r = 0.72, P < 0.001) and moderately correlated with itch intensity scales in the study population (visual analogue scale r = 0.46; numerical rating scale r = 0.51; verbal rating scale r = 0.51, for all: P < 0.001).CONCLUSION: ItchyQoL is now also validated in French, Italian, Polish, Russian, Spanish and Turkish and can be used in clinical trials in countries speaking these languages.
AB - BACKGROUND: Chronic pruritus (CP) is a frequently occurring symptom in inflammatory dermatoses, causing a high burden and limitations to health-related quality of life (HRQoL).OBJECTIVE: The ItchyQoL was developed to assess the impairment to HRQoL in patients with CP. However, it has only been validated in English and German. Here, we report the validation in several languages across Europe.METHODS: After professional translation, the versions of ItchyQoL were digitized for use as a tablet application. Validation was performed in clinics for dermatology in Austria, France, Germany, Italy, Poland, Russia, Spain, Switzerland and Turkey.RESULTS: Five hundred and thirty-five patients with either contact dermatitis, chronic prurigo - nodular type, psoriasis vulgaris, lichen planus or mycosis fungoides/Sézary syndrome and with CP ≥ 3 on the numerical rating scale were included. ItchyQoL showed a high level of consistency (Cronbach's-α, all: 0.95) and test-retest reliability (intraclass correlation: 0.91). It strongly correlated with the Dermatology Life Quality Index (r = 0.72, P < 0.001) and moderately correlated with itch intensity scales in the study population (visual analogue scale r = 0.46; numerical rating scale r = 0.51; verbal rating scale r = 0.51, for all: P < 0.001).CONCLUSION: ItchyQoL is now also validated in French, Italian, Polish, Russian, Spanish and Turkish and can be used in clinical trials in countries speaking these languages.
KW - Adult
KW - Aged
KW - Cross-Sectional Studies
KW - Europe
KW - Female
KW - Humans
KW - International Cooperation
KW - Male
KW - Middle Aged
KW - Pruritus/diagnosis
KW - Psychometrics
KW - Quality of Life/psychology
KW - Risk Assessment
KW - Severity of Illness Index
KW - Skin Diseases/pathology
KW - Young Adult
U2 - 10.1111/jdv.15225
DO - 10.1111/jdv.15225
M3 - SCORING: Journal article
C2 - 30193410
VL - 33
SP - 391
EP - 397
JO - J EUR ACAD DERMATOL
JF - J EUR ACAD DERMATOL
SN - 0926-9959
IS - 2
ER -