Research ExplorerPublicationsCost-utility of a specific collaborative group intervention ...

Cost-utility of a specific collaborative group intervention for patients with functional somatic syndromes

Standard

Cost-utility of a specific collaborative group intervention for patients with functional somatic syndromes. / Konnopka, Alexander; König, Hans-Helmut; Kaufmann, Claudia; Egger, Nina; Wild, Beate; Szecsenyi, Joachim; Herzog, Wolfgang; Schellberg, Dieter; Schaefert, Rainer.

In: J PSYCHOSOM RES, Vol. 90, 11.2016, p. 43-50.

Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

Harvard

Konnopka, A, König, H-H, Kaufmann, C, Egger, N, Wild, B, Szecsenyi, J, Herzog, W, Schellberg, D & Schaefert, R 2016, 'Cost-utility of a specific collaborative group intervention for patients with functional somatic syndromes', J PSYCHOSOM RES, vol. 90, pp. 43-50. https://doi.org/10.1016/j.jpsychores.2016.09.001

APA

Konnopka, A., König, H-H., Kaufmann, C., Egger, N., Wild, B., Szecsenyi, J., Herzog, W., Schellberg, D., & Schaefert, R. (2016). Cost-utility of a specific collaborative group intervention for patients with functional somatic syndromes. J PSYCHOSOM RES, 90, 43-50. https://doi.org/10.1016/j.jpsychores.2016.09.001

Vancouver

Konnopka A, König H-H, Kaufmann C, Egger N, Wild B, Szecsenyi J et al. Cost-utility of a specific collaborative group intervention for patients with functional somatic syndromes. J PSYCHOSOM RES. 2016 Nov;90:43-50. https://doi.org/10.1016/j.jpsychores.2016.09.001

Bibtex

@article{77c78c29f50449829e1ce80381af7b0b,
title = "Cost-utility of a specific collaborative group intervention for patients with functional somatic syndromes",
abstract = "BACKGROUND: Collaborative group intervention (CGI) in patients with functional somatic syndromes (FSS) has been shown to improve mental quality of life.OBJECTIVE: To analyse incremental cost-utility of CGI compared to enhanced medical care in patients with FSS.METHODS: An economic evaluation alongside a cluster-randomised controlled trial was performed. 35 general practitioners (GPs) recruited 300 FSS patients. Patients in the CGI arm were offered 10 group sessions within 3months and 2 booster sessions 6 and 12months after baseline. Costs were assessed via questionnaire. Quality adjusted life years (QALYs) were calculated using the SF-6D index, derived from the 36-item short-form health survey (SF-36). We calculated patients' net-monetary-benefit (NMB), estimated the treatment effect via regression, and generated cost-effectiveness acceptability curves.RESULTS: Using intention-to-treat analysis, total costs during the 12-month study period were 5777EUR in the intervention, and 6858EUR in the control group. Controlling for possible confounders, we found a small, but significant positive intervention effect on QALYs (+0.017; p=0.019) and an insignificant cost saving resulting from a cost-increase in the control group (-10.5%; p=0.278). NMB regression showed that the probability of CGI to be cost-effective was 69% for a willingness to pay (WTP) of 0EUR/QALY, increased to 92% for a WTP of 50,000EUR/QALY and reached the level of 95% at a WTP of 70,375EUR/QALY. Subgroup analyses yielded that CGI was only cost-effective in severe somatic symptom severity (PHQ-15≥15).CONCLUSION: CGI has a high probability to be a cost-effective treatment for FSS, in particular for patients with severe somatic symptom severity.",
author = "Alexander Konnopka and Hans-Helmut K{\"o}nig and Claudia Kaufmann and Nina Egger and Beate Wild and Joachim Szecsenyi and Wolfgang Herzog and Dieter Schellberg and Rainer Schaefert",
note = "Copyright {\textcopyright} 2016 Elsevier Inc. All rights reserved.",
year = "2016",
month = nov,
doi = "10.1016/j.jpsychores.2016.09.001",
language = "English",
volume = "90",
pages = "43--50",
journal = "J PSYCHOSOM RES",
issn = "0022-3999",
publisher = "Elsevier Inc.",

}

RIS

TY - JOUR

T1 - Cost-utility of a specific collaborative group intervention for patients with functional somatic syndromes

AU - Konnopka, Alexander

AU - König, Hans-Helmut

AU - Kaufmann, Claudia

AU - Egger, Nina

AU - Wild, Beate

AU - Szecsenyi, Joachim

AU - Herzog, Wolfgang

AU - Schellberg, Dieter

AU - Schaefert, Rainer

N1 - Copyright © 2016 Elsevier Inc. All rights reserved.

PY - 2016/11

Y1 - 2016/11

N2 - BACKGROUND: Collaborative group intervention (CGI) in patients with functional somatic syndromes (FSS) has been shown to improve mental quality of life.OBJECTIVE: To analyse incremental cost-utility of CGI compared to enhanced medical care in patients with FSS.METHODS: An economic evaluation alongside a cluster-randomised controlled trial was performed. 35 general practitioners (GPs) recruited 300 FSS patients. Patients in the CGI arm were offered 10 group sessions within 3months and 2 booster sessions 6 and 12months after baseline. Costs were assessed via questionnaire. Quality adjusted life years (QALYs) were calculated using the SF-6D index, derived from the 36-item short-form health survey (SF-36). We calculated patients' net-monetary-benefit (NMB), estimated the treatment effect via regression, and generated cost-effectiveness acceptability curves.RESULTS: Using intention-to-treat analysis, total costs during the 12-month study period were 5777EUR in the intervention, and 6858EUR in the control group. Controlling for possible confounders, we found a small, but significant positive intervention effect on QALYs (+0.017; p=0.019) and an insignificant cost saving resulting from a cost-increase in the control group (-10.5%; p=0.278). NMB regression showed that the probability of CGI to be cost-effective was 69% for a willingness to pay (WTP) of 0EUR/QALY, increased to 92% for a WTP of 50,000EUR/QALY and reached the level of 95% at a WTP of 70,375EUR/QALY. Subgroup analyses yielded that CGI was only cost-effective in severe somatic symptom severity (PHQ-15≥15).CONCLUSION: CGI has a high probability to be a cost-effective treatment for FSS, in particular for patients with severe somatic symptom severity.

AB - BACKGROUND: Collaborative group intervention (CGI) in patients with functional somatic syndromes (FSS) has been shown to improve mental quality of life.OBJECTIVE: To analyse incremental cost-utility of CGI compared to enhanced medical care in patients with FSS.METHODS: An economic evaluation alongside a cluster-randomised controlled trial was performed. 35 general practitioners (GPs) recruited 300 FSS patients. Patients in the CGI arm were offered 10 group sessions within 3months and 2 booster sessions 6 and 12months after baseline. Costs were assessed via questionnaire. Quality adjusted life years (QALYs) were calculated using the SF-6D index, derived from the 36-item short-form health survey (SF-36). We calculated patients' net-monetary-benefit (NMB), estimated the treatment effect via regression, and generated cost-effectiveness acceptability curves.RESULTS: Using intention-to-treat analysis, total costs during the 12-month study period were 5777EUR in the intervention, and 6858EUR in the control group. Controlling for possible confounders, we found a small, but significant positive intervention effect on QALYs (+0.017; p=0.019) and an insignificant cost saving resulting from a cost-increase in the control group (-10.5%; p=0.278). NMB regression showed that the probability of CGI to be cost-effective was 69% for a willingness to pay (WTP) of 0EUR/QALY, increased to 92% for a WTP of 50,000EUR/QALY and reached the level of 95% at a WTP of 70,375EUR/QALY. Subgroup analyses yielded that CGI was only cost-effective in severe somatic symptom severity (PHQ-15≥15).CONCLUSION: CGI has a high probability to be a cost-effective treatment for FSS, in particular for patients with severe somatic symptom severity.

U2 - 10.1016/j.jpsychores.2016.09.001

DO - 10.1016/j.jpsychores.2016.09.001

M3 - SCORING: Journal article

C2 - 27772558

VL - 90

SP - 43

EP - 50

JO - J PSYCHOSOM RES

JF - J PSYCHOSOM RES

SN - 0022-3999

ER -