Cost-of-illness studies and cost-effectiveness analyses in anxiety disorders: a systematic review.
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Cost-of-illness studies and cost-effectiveness analyses in anxiety disorders: a systematic review. / Konnopka, Alexander; Leichsenring, Falk; Leibing, Eric; König, Hans-Helmut.
In: J AFFECT DISORDERS, Vol. 114, No. 1-3, 1-3, 2009, p. 14-31.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
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TY - JOUR
T1 - Cost-of-illness studies and cost-effectiveness analyses in anxiety disorders: a systematic review.
AU - Konnopka, Alexander
AU - Leichsenring, Falk
AU - Leibing, Eric
AU - König, Hans-Helmut
PY - 2009
Y1 - 2009
N2 - AIMS: To review cost-of-illness studies (COI) and cost-effectiveness analyses (CEA) conducted for anxiety disorders. METHODS: Based on a database search in Pubmed, PsychINFO and NHS EED, studies were classified according to various criteria. Cost data were inflated and converted to 2005 US-$ purchasing power parities (PPP). RESULTS: We finally identified 20 COI and 11 CEA of which most concentrated on panic disorder (PD) and generalized anxiety disorder (GAD). Differing inclusion of cost categories limited comparability of COI. PD and GAD tended to show higher direct costs per case, but lower direct cost per inhabitant than social and specific phobias. Different measures of effectiveness severely limited comparability of CEA. Overall CEA analysed 26 therapeutic or interventional strategies mostly compared to standard treatment, 8 of them resulting in lower better effectiveness and costs than the comparator. CONCLUSIONS: Anxiety disorders cause considerable costs. More research on phobias, more standardised inclusion of cost categories in COI and a wider use of comparable effectiveness measures (like QALYs) in CEA is needed.
AB - AIMS: To review cost-of-illness studies (COI) and cost-effectiveness analyses (CEA) conducted for anxiety disorders. METHODS: Based on a database search in Pubmed, PsychINFO and NHS EED, studies were classified according to various criteria. Cost data were inflated and converted to 2005 US-$ purchasing power parities (PPP). RESULTS: We finally identified 20 COI and 11 CEA of which most concentrated on panic disorder (PD) and generalized anxiety disorder (GAD). Differing inclusion of cost categories limited comparability of COI. PD and GAD tended to show higher direct costs per case, but lower direct cost per inhabitant than social and specific phobias. Different measures of effectiveness severely limited comparability of CEA. Overall CEA analysed 26 therapeutic or interventional strategies mostly compared to standard treatment, 8 of them resulting in lower better effectiveness and costs than the comparator. CONCLUSIONS: Anxiety disorders cause considerable costs. More research on phobias, more standardised inclusion of cost categories in COI and a wider use of comparable effectiveness measures (like QALYs) in CEA is needed.
KW - Humans
KW - Psychiatric Status Rating Scales
KW - Anxiety Disorders economics
KW - Cost-Benefit Analysis
KW - Cost of Illness
KW - Treatment Outcome
KW - Panic Disorder economics
KW - Phobic Disorders economics
KW - Humans
KW - Psychiatric Status Rating Scales
KW - Anxiety Disorders economics
KW - Cost-Benefit Analysis
KW - Cost of Illness
KW - Treatment Outcome
KW - Panic Disorder economics
KW - Phobic Disorders economics
M3 - SCORING: Zeitschriftenaufsatz
VL - 114
SP - 14
EP - 31
JO - J AFFECT DISORDERS
JF - J AFFECT DISORDERS
SN - 0165-0327
IS - 1-3
M1 - 1-3
ER -
