Correcting eddy current and motion effects by affine whole-brain registrations
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Correcting eddy current and motion effects by affine whole-brain registrations : evaluation of three-dimensional distortions and comparison with slicewise correction. / Mohammadi, Siawoosh; Möller, Harald E; Kugel, Harald; Müller, Dirk K; Deppe, Michael.
In: MAGN RESON MED, Vol. 64, No. 4, 01.10.2010, p. 1047-56.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
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TY - JOUR
T1 - Correcting eddy current and motion effects by affine whole-brain registrations
T2 - evaluation of three-dimensional distortions and comparison with slicewise correction
AU - Mohammadi, Siawoosh
AU - Möller, Harald E
AU - Kugel, Harald
AU - Müller, Dirk K
AU - Deppe, Michael
PY - 2010/10/1
Y1 - 2010/10/1
N2 - Eddy-current (EC) and motion effects in diffusion-tensor imaging (DTI) bias the estimation of quantitative diffusion indices, such as the fractional anisotropy. Both effects can be retrospectively corrected by registering the strongly distorted diffusion-weighted images to less-distorted T2-weighted images acquired without diffusion weighting. Two different affine spatial transformations are usually employed for this correction: slicewise and whole-brain transformations. However, a relation between estimated transformation parameters and EC distortions has not been established yet for the latter approach. In this study, a novel diffusion-gradient-direction-independent estimation of the EC field is proposed based solely on affine whole-brain registration parameters. Using this model, it is demonstrated that a more distinct evaluation of the whole-brain EC effects is possible if the through-plane distortion was considered in addition to the well-known in-plane distortions. Moreover, a comparison of different whole-brain registrations relative to a slicewise approach is performed, in terms of the relative tensor error. Our findings suggest that for appropriate intersubject comparison of DTI data, a whole-brain registration containing nine affine parameters provides comparable performance (between 0 and 3%) to slicewise methods and can be performed in a fraction of the time.
AB - Eddy-current (EC) and motion effects in diffusion-tensor imaging (DTI) bias the estimation of quantitative diffusion indices, such as the fractional anisotropy. Both effects can be retrospectively corrected by registering the strongly distorted diffusion-weighted images to less-distorted T2-weighted images acquired without diffusion weighting. Two different affine spatial transformations are usually employed for this correction: slicewise and whole-brain transformations. However, a relation between estimated transformation parameters and EC distortions has not been established yet for the latter approach. In this study, a novel diffusion-gradient-direction-independent estimation of the EC field is proposed based solely on affine whole-brain registration parameters. Using this model, it is demonstrated that a more distinct evaluation of the whole-brain EC effects is possible if the through-plane distortion was considered in addition to the well-known in-plane distortions. Moreover, a comparison of different whole-brain registrations relative to a slicewise approach is performed, in terms of the relative tensor error. Our findings suggest that for appropriate intersubject comparison of DTI data, a whole-brain registration containing nine affine parameters provides comparable performance (between 0 and 3%) to slicewise methods and can be performed in a fraction of the time.
KW - Adult
KW - Algorithms
KW - Artifacts
KW - Brain
KW - Diffusion Magnetic Resonance Imaging
KW - Female
KW - Humans
KW - Image Enhancement
KW - Image Interpretation, Computer-Assisted
KW - Imaging, Three-Dimensional
KW - Male
KW - Pattern Recognition, Automated
KW - Reproducibility of Results
KW - Sensitivity and Specificity
KW - Subtraction Technique
U2 - 10.1002/mrm.22501
DO - 10.1002/mrm.22501
M3 - SCORING: Journal article
C2 - 20574966
VL - 64
SP - 1047
EP - 1056
JO - MAGN RESON MED
JF - MAGN RESON MED
SN - 0740-3194
IS - 4
ER -