Contextual novelty modulates the neural dynamics of reward anticipation.
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Contextual novelty modulates the neural dynamics of reward anticipation. / Bunzeck, Nico; Guitart-Masip, Marc; Dolan, Ray J; Düzel, Emrah.
In: J NEUROSCI, Vol. 31, No. 36, 36, 2011, p. 12816-12822.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
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TY - JOUR
T1 - Contextual novelty modulates the neural dynamics of reward anticipation.
AU - Bunzeck, Nico
AU - Guitart-Masip, Marc
AU - Dolan, Ray J
AU - Düzel, Emrah
PY - 2011
Y1 - 2011
N2 - We investigated how rapidly the reward-predicting properties of visual cues are signaled in the human brain and the extent these reward prediction signals are contextually modifiable. In a magnetoencephalography study, we presented participants with fractal visual cues that predicted monetary rewards with different probabilities. These cues were presented in the temporal context of a preceding novel or familiar image of a natural scene. Starting at ?100 ms after cue onset, reward probability was signaled in the event-related fields (ERFs) over temporo-occipital sensors and in the power of theta (5-8 Hz) and beta (20-30 Hz) band oscillations over frontal sensors. While theta decreased with reward probability beta power showed the opposite effect. Thus, in humans anticipatory reward responses are generated rapidly, within 100 ms after the onset of reward-predicting cues, which is similar to the timing established in non-human primates. Contextual novelty enhanced the reward anticipation responses in both ERFs and in beta oscillations starting at ?100 ms after cue onset. This very early context effect is compatible with a physiological model that invokes the mediation of a hippocampal-VTA loop according to which novelty modulates neural response properties within the reward circuitry. We conclude that the neural processing of cues that predict future rewards is temporally highly efficient and contextually modifiable.
AB - We investigated how rapidly the reward-predicting properties of visual cues are signaled in the human brain and the extent these reward prediction signals are contextually modifiable. In a magnetoencephalography study, we presented participants with fractal visual cues that predicted monetary rewards with different probabilities. These cues were presented in the temporal context of a preceding novel or familiar image of a natural scene. Starting at ?100 ms after cue onset, reward probability was signaled in the event-related fields (ERFs) over temporo-occipital sensors and in the power of theta (5-8 Hz) and beta (20-30 Hz) band oscillations over frontal sensors. While theta decreased with reward probability beta power showed the opposite effect. Thus, in humans anticipatory reward responses are generated rapidly, within 100 ms after the onset of reward-predicting cues, which is similar to the timing established in non-human primates. Contextual novelty enhanced the reward anticipation responses in both ERFs and in beta oscillations starting at ?100 ms after cue onset. This very early context effect is compatible with a physiological model that invokes the mediation of a hippocampal-VTA loop according to which novelty modulates neural response properties within the reward circuitry. We conclude that the neural processing of cues that predict future rewards is temporally highly efficient and contextually modifiable.
KW - Adult
KW - Humans
KW - Male
KW - Female
KW - Young Adult
KW - Photic Stimulation
KW - Magnetic Resonance Imaging
KW - Electroencephalography
KW - Theta Rhythm
KW - Evoked Potentials/physiology
KW - Psychomotor Performance/physiology
KW - Magnetoencephalography
KW - Brain/physiology
KW - Reward
KW - Anticipation, Psychological/physiology
KW - Recognition (Psychology)/physiology
KW - Cues
KW - Reaction Time/physiology
KW - Visual Perception
KW - Beta Rhythm
KW - Fractals
KW - Adult
KW - Humans
KW - Male
KW - Female
KW - Young Adult
KW - Photic Stimulation
KW - Magnetic Resonance Imaging
KW - Electroencephalography
KW - Theta Rhythm
KW - Evoked Potentials/physiology
KW - Psychomotor Performance/physiology
KW - Magnetoencephalography
KW - Brain/physiology
KW - Reward
KW - Anticipation, Psychological/physiology
KW - Recognition (Psychology)/physiology
KW - Cues
KW - Reaction Time/physiology
KW - Visual Perception
KW - Beta Rhythm
KW - Fractals
M3 - SCORING: Journal article
VL - 31
SP - 12816
EP - 12822
JO - J NEUROSCI
JF - J NEUROSCI
SN - 0270-6474
IS - 36
M1 - 36
ER -