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Consistent lowering of clotting factors for the treatment of acute cardiovascular syndromes and hypercoagulability: a different pathophysiological approach

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Consistent lowering of clotting factors for the treatment of acute cardiovascular syndromes and hypercoagulability: a different pathophysiological approach. / Jaeger, B R; Goehring, P; Schirmer, J; Uhrig, S; Lohse, P; Kreuzer, E; Reichart, B; Seidel, D.

In: THER APHER DIAL, Vol. 5, No. 4, 08.2001, p. 252-259.

Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

Harvard

Jaeger, BR, Goehring, P, Schirmer, J, Uhrig, S, Lohse, P, Kreuzer, E, Reichart, B & Seidel, D 2001, 'Consistent lowering of clotting factors for the treatment of acute cardiovascular syndromes and hypercoagulability: a different pathophysiological approach', THER APHER DIAL, vol. 5, no. 4, pp. 252-259. https://doi.org/10.1046/j.1526-0968.2001.00350.x

APA

Jaeger, B. R., Goehring, P., Schirmer, J., Uhrig, S., Lohse, P., Kreuzer, E., Reichart, B., & Seidel, D. (2001). Consistent lowering of clotting factors for the treatment of acute cardiovascular syndromes and hypercoagulability: a different pathophysiological approach. THER APHER DIAL, 5(4), 252-259. https://doi.org/10.1046/j.1526-0968.2001.00350.x

Vancouver

Jaeger BR, Goehring P, Schirmer J, Uhrig S, Lohse P, Kreuzer E et al. Consistent lowering of clotting factors for the treatment of acute cardiovascular syndromes and hypercoagulability: a different pathophysiological approach. THER APHER DIAL. 2001 Aug;5(4):252-259. https://doi.org/10.1046/j.1526-0968.2001.00350.x

Bibtex

@article{f0f4cacec57f482c99d1df72738bf59d,
title = "Consistent lowering of clotting factors for the treatment of acute cardiovascular syndromes and hypercoagulability: a different pathophysiological approach",
abstract = "Hypercoagulability is a key contributor to acute cardiovascular syndromes and to various microcirculatory disorders. The use of heparin-mediated extracorporeal low-density lipoprotein/fibrinogen precipitation (HELP) apheresis makes a controlled, immediately effective reduction of clotting factors possible, and induces subsequent positive effects on plasma viscosity, erythrocyte aggregation, and microcirculation. Oxygen supply to an ischemic artery can thus be increased without hemodilution, qualifying the HELP system as a possible therapeutic tool in the treatment of acute cardiovascular syndromes and microcirculatory disorders.",
keywords = "Aged, Blood Coagulation/physiology, Blood Coagulation Disorders/therapy, Blood Coagulation Factors/analysis, Cardiovascular Diseases/therapy, Coronary Artery Disease/prevention & control, Coronary Thrombosis/prevention & control, Female, Hemorheology, Humans, Hypercholesterolemia/therapy, Male, Middle Aged, Plasmapheresis/methods",
author = "Jaeger, {B R} and P Goehring and J Schirmer and S Uhrig and P Lohse and E Kreuzer and B Reichart and D Seidel",
year = "2001",
month = aug,
doi = "10.1046/j.1526-0968.2001.00350.x",
language = "English",
volume = "5",
pages = "252--259",
journal = "THER APHER DIAL",
issn = "1744-9979",
publisher = "Wiley-Blackwell",
number = "4",

}

RIS

TY - JOUR

T1 - Consistent lowering of clotting factors for the treatment of acute cardiovascular syndromes and hypercoagulability: a different pathophysiological approach

AU - Jaeger, B R

AU - Goehring, P

AU - Schirmer, J

AU - Uhrig, S

AU - Lohse, P

AU - Kreuzer, E

AU - Reichart, B

AU - Seidel, D

PY - 2001/8

Y1 - 2001/8

N2 - Hypercoagulability is a key contributor to acute cardiovascular syndromes and to various microcirculatory disorders. The use of heparin-mediated extracorporeal low-density lipoprotein/fibrinogen precipitation (HELP) apheresis makes a controlled, immediately effective reduction of clotting factors possible, and induces subsequent positive effects on plasma viscosity, erythrocyte aggregation, and microcirculation. Oxygen supply to an ischemic artery can thus be increased without hemodilution, qualifying the HELP system as a possible therapeutic tool in the treatment of acute cardiovascular syndromes and microcirculatory disorders.

AB - Hypercoagulability is a key contributor to acute cardiovascular syndromes and to various microcirculatory disorders. The use of heparin-mediated extracorporeal low-density lipoprotein/fibrinogen precipitation (HELP) apheresis makes a controlled, immediately effective reduction of clotting factors possible, and induces subsequent positive effects on plasma viscosity, erythrocyte aggregation, and microcirculation. Oxygen supply to an ischemic artery can thus be increased without hemodilution, qualifying the HELP system as a possible therapeutic tool in the treatment of acute cardiovascular syndromes and microcirculatory disorders.

KW - Aged

KW - Blood Coagulation/physiology

KW - Blood Coagulation Disorders/therapy

KW - Blood Coagulation Factors/analysis

KW - Cardiovascular Diseases/therapy

KW - Coronary Artery Disease/prevention & control

KW - Coronary Thrombosis/prevention & control

KW - Female

KW - Hemorheology

KW - Humans

KW - Hypercholesterolemia/therapy

KW - Male

KW - Middle Aged

KW - Plasmapheresis/methods

U2 - 10.1046/j.1526-0968.2001.00350.x

DO - 10.1046/j.1526-0968.2001.00350.x

M3 - SCORING: Journal article

C2 - 11724509

VL - 5

SP - 252

EP - 259

JO - THER APHER DIAL

JF - THER APHER DIAL

SN - 1744-9979

IS - 4

ER -