Considering DSM-5: personality diagnostics in patients with schizophrenia spectrum disorders.
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Considering DSM-5: personality diagnostics in patients with schizophrenia spectrum disorders. / Schröder, Katrin; Hoppe, Annelene; Andresen, Burkhard; Naber, Dieter; Lammers, Claas-Hinrich; Huber, Christian.
In: PSYCHIATRY, Vol. 75, No. 2, 2, 2012, p. 120-134.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
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TY - JOUR
T1 - Considering DSM-5: personality diagnostics in patients with schizophrenia spectrum disorders.
AU - Schröder, Katrin
AU - Hoppe, Annelene
AU - Andresen, Burkhard
AU - Naber, Dieter
AU - Lammers, Claas-Hinrich
AU - Huber, Christian
PY - 2012
Y1 - 2012
N2 - The aims of this study were to examine the prevalence of personality disorders (PD) in patients with schizophrenia spectrum disorders (SSD), to examine the interaction of axis-I and axis-II symptoms to provide an estimate on the confounding potential of SSD psychopathology in the establishment of DSM-IV PD diagnoses, and to discuss implications concerning the proposed changes in DSM-5. Patients with SSD, aged 18 to 65 years, and being at least partially remitted (PANSS total score <75) were included. PD was examined categorically and dimensionally using the SCID-II screening questionnaire and interview, and SSD psychopathology was rated using the Positive and Negative Syndrome Scale for Schizophrenia (PANSS). Forty-five patients (31 with schizophrenia) were included in the current study. Mean age was 37.2 years, and the median duration of illness was 9.5 years. Mean PANSS total score was 42.5. The cumulative prevalence of PD in our collective was 20%, with obsessive-compulsive, antisocial, and borderline PD being the most frequent. There were no cases of cluster A PD diagnoses. In the dimensional analysis, numerous correlations of small to medium effect size emerged between maladaptive personality traits and SSD psychopathology. PD is present in a clinically relevant subgroup of SSD patients and has to be recognized in SSD treatment. Currently, it remains unclear to what extent correlations between personality traits and SSD symptoms can be explained by content overlap or co-variation of SSD psychopathology and PD traits. SSD psychopathology may bias PD diagnostics and lead to a higher percentage of categorical PD diagnoses, especially considering the proposed changes in DSM-5.
AB - The aims of this study were to examine the prevalence of personality disorders (PD) in patients with schizophrenia spectrum disorders (SSD), to examine the interaction of axis-I and axis-II symptoms to provide an estimate on the confounding potential of SSD psychopathology in the establishment of DSM-IV PD diagnoses, and to discuss implications concerning the proposed changes in DSM-5. Patients with SSD, aged 18 to 65 years, and being at least partially remitted (PANSS total score <75) were included. PD was examined categorically and dimensionally using the SCID-II screening questionnaire and interview, and SSD psychopathology was rated using the Positive and Negative Syndrome Scale for Schizophrenia (PANSS). Forty-five patients (31 with schizophrenia) were included in the current study. Mean age was 37.2 years, and the median duration of illness was 9.5 years. Mean PANSS total score was 42.5. The cumulative prevalence of PD in our collective was 20%, with obsessive-compulsive, antisocial, and borderline PD being the most frequent. There were no cases of cluster A PD diagnoses. In the dimensional analysis, numerous correlations of small to medium effect size emerged between maladaptive personality traits and SSD psychopathology. PD is present in a clinically relevant subgroup of SSD patients and has to be recognized in SSD treatment. Currently, it remains unclear to what extent correlations between personality traits and SSD symptoms can be explained by content overlap or co-variation of SSD psychopathology and PD traits. SSD psychopathology may bias PD diagnostics and lead to a higher percentage of categorical PD diagnoses, especially considering the proposed changes in DSM-5.
KW - Adult
KW - Comorbidity
KW - Humans
KW - Male
KW - Aged
KW - Female
KW - Middle Aged
KW - Psychiatric Status Rating Scales
KW - Adolescent
KW - Young Adult
KW - Treatment Outcome
KW - Cross-Sectional Studies
KW - Prevalence
KW - Interview, Psychological
KW - Schizophrenic Psychology
KW - Diagnostic and Statistical Manual of Mental Disorders
KW - Personality Disorders/classification/diagnosis/epidemiology
KW - Schizophrenia/diagnosis/epidemiology
KW - Adult
KW - Comorbidity
KW - Humans
KW - Male
KW - Aged
KW - Female
KW - Middle Aged
KW - Psychiatric Status Rating Scales
KW - Adolescent
KW - Young Adult
KW - Treatment Outcome
KW - Cross-Sectional Studies
KW - Prevalence
KW - Interview, Psychological
KW - Schizophrenic Psychology
KW - Diagnostic and Statistical Manual of Mental Disorders
KW - Personality Disorders/classification/diagnosis/epidemiology
KW - Schizophrenia/diagnosis/epidemiology
M3 - SCORING: Journal article
VL - 75
SP - 120
EP - 134
JO - PSYCHIATRY
JF - PSYCHIATRY
SN - 0033-2747
IS - 2
M1 - 2
ER -
