Consensus statement on the symptom-based treatment of chronic venous diseases
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Consensus statement on the symptom-based treatment of chronic venous diseases. / Stücker, Markus; Debus, Eike Sebastian; Hoffmann, Johannes; Jünger, Michael; Kröger, Knut; Mumme, Achim; Ramelet, Albert-Adrien; Rabe, Eberhard.
In: J DTSCH DERMATOL GES, Vol. 14, No. 6, 06.2016, p. 575-83.Research output: SCORING: Contribution to journal › SCORING: Review article › Research
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TY - JOUR
T1 - Consensus statement on the symptom-based treatment of chronic venous diseases
AU - Stücker, Markus
AU - Debus, Eike Sebastian
AU - Hoffmann, Johannes
AU - Jünger, Michael
AU - Kröger, Knut
AU - Mumme, Achim
AU - Ramelet, Albert-Adrien
AU - Rabe, Eberhard
N1 - © 2016 Deutsche Dermatologische Gesellschaft (DDG). Published by John Wiley & Sons Ltd.
PY - 2016/6
Y1 - 2016/6
N2 - BACKGROUND: Chronic venous diseases are very common. Early symptoms such as a sensation of swelling and heaviness may occur without objectifiable findings, but are nevertheless perceived as bothersome. Progressive disease - marked by varicose veins and symptoms of chronic venous insufficiency - is associated with considerable impairment in quality of life.METHODS: The present consensus recommendations are based on publications in Pubmed-listed journals as well as relevant international therapeutic guidelines on chronic venous diseases. Only conclusive randomized controlled trials (RCTs) and review articles/meta-analyses were included.RESULTS: Symptom-based treatment of chronic venous diseases is based on three therapeutic pillars with proven efficacy: invasive therapy, compression therapy, and oral pharmacological treatment. According to current therapeutic guidelines, invasive procedures aimed at restoring unimpaired venous blood flow as well as improving or eliminating pathological changes should be the first-line approach. If an invasive approach is infeasible or undesirable, or if symptoms persist following a therapeutic intervention, optimal use of symptom-based treatment options is recommended. Compression and pharmacological therapy may each be used as sole treatment or in combination. To guarantee maximum therapeutic success, individual treatment decisions should be made on a case-by-case basis.CONCLUSIONS: Chronic venous diseases should be treated on the basis of individual pathophysiological disturbances. Symptom-based treatment of chronic venous disorders encompasses invasive therapy, compression therapy, and oral pharmacological therapy. Considerations in choosing the appropriate treatment option should include both objective signs as well as subjective symptoms.
AB - BACKGROUND: Chronic venous diseases are very common. Early symptoms such as a sensation of swelling and heaviness may occur without objectifiable findings, but are nevertheless perceived as bothersome. Progressive disease - marked by varicose veins and symptoms of chronic venous insufficiency - is associated with considerable impairment in quality of life.METHODS: The present consensus recommendations are based on publications in Pubmed-listed journals as well as relevant international therapeutic guidelines on chronic venous diseases. Only conclusive randomized controlled trials (RCTs) and review articles/meta-analyses were included.RESULTS: Symptom-based treatment of chronic venous diseases is based on three therapeutic pillars with proven efficacy: invasive therapy, compression therapy, and oral pharmacological treatment. According to current therapeutic guidelines, invasive procedures aimed at restoring unimpaired venous blood flow as well as improving or eliminating pathological changes should be the first-line approach. If an invasive approach is infeasible or undesirable, or if symptoms persist following a therapeutic intervention, optimal use of symptom-based treatment options is recommended. Compression and pharmacological therapy may each be used as sole treatment or in combination. To guarantee maximum therapeutic success, individual treatment decisions should be made on a case-by-case basis.CONCLUSIONS: Chronic venous diseases should be treated on the basis of individual pathophysiological disturbances. Symptom-based treatment of chronic venous disorders encompasses invasive therapy, compression therapy, and oral pharmacological therapy. Considerations in choosing the appropriate treatment option should include both objective signs as well as subjective symptoms.
KW - Chronic Disease
KW - Consensus
KW - Humans
KW - Meta-Analysis as Topic
KW - Practice Guidelines as Topic
KW - Quality of Life
KW - Randomized Controlled Trials as Topic
KW - Varicose Veins
KW - Venous Insufficiency/therapy
U2 - 10.1111/ddg.13006
DO - 10.1111/ddg.13006
M3 - SCORING: Review article
C2 - 27240062
VL - 14
SP - 575
EP - 583
JO - J DTSCH DERMATOL GES
JF - J DTSCH DERMATOL GES
SN - 1610-0379
IS - 6
ER -