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Concomitant surgical ablation for atrial fibrillation (AF) in patients with significant atrial dilation >55 mm. Worth the effort?

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Concomitant surgical ablation for atrial fibrillation (AF) in patients with significant atrial dilation >55 mm. Worth the effort? / Pecha, Simon; Hakmi, Samer; Subbotina, Irina; Willems, Stephan; Reichenspurner, Hermann; Wagner, Florian Mathias.

In: J CARDIOTHORAC SURG, Vol. 10, 14.11.2015, p. 165.

Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

Harvard

Pecha, S, Hakmi, S, Subbotina, I, Willems, S, Reichenspurner, H & Wagner, FM 2015, 'Concomitant surgical ablation for atrial fibrillation (AF) in patients with significant atrial dilation >55 mm. Worth the effort?', J CARDIOTHORAC SURG, vol. 10, pp. 165. https://doi.org/10.1186/s13019-015-0337-3

APA

Pecha, S., Hakmi, S., Subbotina, I., Willems, S., Reichenspurner, H., & Wagner, F. M. (2015). Concomitant surgical ablation for atrial fibrillation (AF) in patients with significant atrial dilation >55 mm. Worth the effort? J CARDIOTHORAC SURG, 10, 165. https://doi.org/10.1186/s13019-015-0337-3

Vancouver

Pecha S, Hakmi S, Subbotina I, Willems S, Reichenspurner H, Wagner FM. Concomitant surgical ablation for atrial fibrillation (AF) in patients with significant atrial dilation >55 mm. Worth the effort? J CARDIOTHORAC SURG. 2015 Nov 14;10:165. https://doi.org/10.1186/s13019-015-0337-3

Bibtex

@article{9e5a9909cff74006b2a330e080b2a6ae,
title = "Concomitant surgical ablation for atrial fibrillation (AF) in patients with significant atrial dilation >55 mm. Worth the effort?",
abstract = "BACKGROUND: Concomitant Surgical AF ablation is an established procedure, recommended in guidelines. However many surgeons are reluctant to perform AF ablation in patients with significantly enlarged left atrium. We therefore analyzed outcomes of patients with left-atrial diameter >55 mm undergoing concomitant AF ablation.METHODS: Between 05/2003 and 12/2012 124 patients with significantly enlarged left-atrium >55 mm underwent concomitant surgical AF ablation. Rhythm monitoring was accomplished by implantable loop recorder (ILR) interrogation (n = 54), or 24-h Holter-ECG (n = 70). Successful ablation was defined as AF Burden <0.5 % in ILR interrogation or absence of AF episode >30 s in 24-h Holter-ECG. Primary endpoint of the study was freedom from AF at 12 months follow-up.RESULTS: Mean patient's age was 65.7+/-9.6 years, 69.4 % were male. No major ablation or ILR related complications occurred. Mean LA diameter was 60.7+/-4.4 mm. Survival rate at one-year follow up was 94.4 %. 11 (8.8 %) patients received additional catheter-based ablation, while 23 (18.5 %) had an electrical cardioversion during follow-up period. Overall freedom from AF rate after one-year follow-up was 64.4 % and 59.4 % off antiarrhythmic drugs respectively. Logistic regression analysis identified preoperative paroxysmal AF, duration of AF and LA diameter > 70 mm as predictors for rhythm outcome at 12 months follow-up.CONCLUSION: In this patient cohort with significantly enlarged LA diameter, concomitant surgical AF ablation provided freedom from AF of 64.4 % after one-year follow-up. However in this patient population, an accurate postoperative care with interventions like medical or- electrical cardioversion and additional catheter based ablation is necessary to achieve satisfactory results.",
keywords = "Aged, Atrial Fibrillation/complications, Cardiomyopathy, Dilated/diagnosis, Catheter Ablation/methods, Echocardiography, Female, Heart Atria, Humans, Male, Treatment Outcome",
author = "Simon Pecha and Samer Hakmi and Irina Subbotina and Stephan Willems and Hermann Reichenspurner and Wagner, {Florian Mathias}",
year = "2015",
month = nov,
day = "14",
doi = "10.1186/s13019-015-0337-3",
language = "English",
volume = "10",
pages = "165",
journal = "J CARDIOTHORAC SURG",
issn = "1749-8090",
publisher = "BioMed Central Ltd.",

}

RIS

TY - JOUR

T1 - Concomitant surgical ablation for atrial fibrillation (AF) in patients with significant atrial dilation >55 mm. Worth the effort?

AU - Pecha, Simon

AU - Hakmi, Samer

AU - Subbotina, Irina

AU - Willems, Stephan

AU - Reichenspurner, Hermann

AU - Wagner, Florian Mathias

PY - 2015/11/14

Y1 - 2015/11/14

N2 - BACKGROUND: Concomitant Surgical AF ablation is an established procedure, recommended in guidelines. However many surgeons are reluctant to perform AF ablation in patients with significantly enlarged left atrium. We therefore analyzed outcomes of patients with left-atrial diameter >55 mm undergoing concomitant AF ablation.METHODS: Between 05/2003 and 12/2012 124 patients with significantly enlarged left-atrium >55 mm underwent concomitant surgical AF ablation. Rhythm monitoring was accomplished by implantable loop recorder (ILR) interrogation (n = 54), or 24-h Holter-ECG (n = 70). Successful ablation was defined as AF Burden <0.5 % in ILR interrogation or absence of AF episode >30 s in 24-h Holter-ECG. Primary endpoint of the study was freedom from AF at 12 months follow-up.RESULTS: Mean patient's age was 65.7+/-9.6 years, 69.4 % were male. No major ablation or ILR related complications occurred. Mean LA diameter was 60.7+/-4.4 mm. Survival rate at one-year follow up was 94.4 %. 11 (8.8 %) patients received additional catheter-based ablation, while 23 (18.5 %) had an electrical cardioversion during follow-up period. Overall freedom from AF rate after one-year follow-up was 64.4 % and 59.4 % off antiarrhythmic drugs respectively. Logistic regression analysis identified preoperative paroxysmal AF, duration of AF and LA diameter > 70 mm as predictors for rhythm outcome at 12 months follow-up.CONCLUSION: In this patient cohort with significantly enlarged LA diameter, concomitant surgical AF ablation provided freedom from AF of 64.4 % after one-year follow-up. However in this patient population, an accurate postoperative care with interventions like medical or- electrical cardioversion and additional catheter based ablation is necessary to achieve satisfactory results.

AB - BACKGROUND: Concomitant Surgical AF ablation is an established procedure, recommended in guidelines. However many surgeons are reluctant to perform AF ablation in patients with significantly enlarged left atrium. We therefore analyzed outcomes of patients with left-atrial diameter >55 mm undergoing concomitant AF ablation.METHODS: Between 05/2003 and 12/2012 124 patients with significantly enlarged left-atrium >55 mm underwent concomitant surgical AF ablation. Rhythm monitoring was accomplished by implantable loop recorder (ILR) interrogation (n = 54), or 24-h Holter-ECG (n = 70). Successful ablation was defined as AF Burden <0.5 % in ILR interrogation or absence of AF episode >30 s in 24-h Holter-ECG. Primary endpoint of the study was freedom from AF at 12 months follow-up.RESULTS: Mean patient's age was 65.7+/-9.6 years, 69.4 % were male. No major ablation or ILR related complications occurred. Mean LA diameter was 60.7+/-4.4 mm. Survival rate at one-year follow up was 94.4 %. 11 (8.8 %) patients received additional catheter-based ablation, while 23 (18.5 %) had an electrical cardioversion during follow-up period. Overall freedom from AF rate after one-year follow-up was 64.4 % and 59.4 % off antiarrhythmic drugs respectively. Logistic regression analysis identified preoperative paroxysmal AF, duration of AF and LA diameter > 70 mm as predictors for rhythm outcome at 12 months follow-up.CONCLUSION: In this patient cohort with significantly enlarged LA diameter, concomitant surgical AF ablation provided freedom from AF of 64.4 % after one-year follow-up. However in this patient population, an accurate postoperative care with interventions like medical or- electrical cardioversion and additional catheter based ablation is necessary to achieve satisfactory results.

KW - Aged

KW - Atrial Fibrillation/complications

KW - Cardiomyopathy, Dilated/diagnosis

KW - Catheter Ablation/methods

KW - Echocardiography

KW - Female

KW - Heart Atria

KW - Humans

KW - Male

KW - Treatment Outcome

U2 - 10.1186/s13019-015-0337-3

DO - 10.1186/s13019-015-0337-3

M3 - SCORING: Journal article

C2 - 26577821

VL - 10

SP - 165

JO - J CARDIOTHORAC SURG

JF - J CARDIOTHORAC SURG

SN - 1749-8090

ER -