Complement factor H-related protein 1 deficiency and factor H antibodies in pediatric patients with atypical hemolytic uremic syndrome.

  • Johannes Hofer
  • Andreas R Janecke
  • L B Zimmerhackl
  • Magdalena Riedl
  • Alejandra Rosales
  • Thomas Giner
  • Gerard Cortina
  • Carola J Haindl
  • Barbara Petzelberger
  • Miriam Pawlik
  • Verena Jeller
  • Udo Vester
  • Bettina Gadner
  • Michel Van Husen
  • Michael L Moritz
  • Reinhard Würzner
  • Therese Jungraithmayr
  • German-Austrian HUS Study Group

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Abstract

This study evaluated the relevance of complement factor H (CFH)-related protein (CFHR) 1 deficiency in pediatric patients with atypical hemolytic uremic syndrome (aHUS) by evaluating both the frequency of deletions in CFHR1 and the presence of complement factor H (CFH) antibodies.

Bibliographical data

Original languageEnglish
Article number3
ISSN1555-9041
Publication statusPublished - 2013
pubmed 23243267