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Comparison of nine prognostic scores in patients with brain metastases of breast cancer receiving radiotherapy of the brain

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Comparison of nine prognostic scores in patients with brain metastases of breast cancer receiving radiotherapy of the brain. / Laakmann, Elena; Riecke, Kerstin; Goy, Yvonne; Kersten, Jan F; Krüll, Andreas; Müller, Volkmar; Petersen, Cordula; Witzel, Isabell.

In: J CANCER RES CLIN, Vol. 142, No. 1, 01.01.2016, p. 325-32.

Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

Harvard

Laakmann, E, Riecke, K, Goy, Y, Kersten, JF, Krüll, A, Müller, V, Petersen, C & Witzel, I 2016, 'Comparison of nine prognostic scores in patients with brain metastases of breast cancer receiving radiotherapy of the brain', J CANCER RES CLIN, vol. 142, no. 1, pp. 325-32. https://doi.org/10.1007/s00432-015-2049-4

APA

Laakmann, E., Riecke, K., Goy, Y., Kersten, J. F., Krüll, A., Müller, V., Petersen, C., & Witzel, I. (2016). Comparison of nine prognostic scores in patients with brain metastases of breast cancer receiving radiotherapy of the brain. J CANCER RES CLIN, 142(1), 325-32. https://doi.org/10.1007/s00432-015-2049-4

Vancouver

Laakmann E, Riecke K, Goy Y, Kersten JF, Krüll A, Müller V et al. Comparison of nine prognostic scores in patients with brain metastases of breast cancer receiving radiotherapy of the brain. J CANCER RES CLIN. 2016 Jan 1;142(1):325-32. https://doi.org/10.1007/s00432-015-2049-4

Bibtex

@article{a1b04b6a621e490ca7224fdf6f95cabb,
title = "Comparison of nine prognostic scores in patients with brain metastases of breast cancer receiving radiotherapy of the brain",
abstract = "PURPOSE: Several prognostic indices (PI) have been developed to stratify patients with brain metastases in groups with good or bad prognosis. The aim of our study was to compare nine prognostic scores for patients with brain metastases (BM) of breast cancer receiving radiotherapy.METHODS: The clinical data of 139 breast cancer patients with BM were collected retrospectively. All patients were treated with cerebral radiotherapy or surgery followed by radiotherapy between January 2007 and December 2012. The prognostic value and accuracy of recursive partitioning analysis (RPA), RPA II, graded prognostic assessment (GPA), basic score for BM, Breast-RPA, Breast-GPA, Rades Score 2011, Germany Score and Breast Rades Score were assessed.RESULTS: The median survival after BM diagnosis in our cohort was 14 months. The overall 6-month, 1-, 2- and 3-year survival rates were 49.6, 37.4, 20.9 and 13.7 %, respectively. Most of the PI were associated with OS, but univariate analysis favored GPA regarding OS. GPA was the most accurate score to identify patients with long (longer than 12 months) and Breast-GPA patients with short (<3 months) life expectancy.CONCLUSIONS: GPA and Breast-GPA seem to be the most useful scores and perform better than other PI for breast cancer patients with BM receiving radiotherapy.",
author = "Elena Laakmann and Kerstin Riecke and Yvonne Goy and Kersten, {Jan F} and Andreas Kr{\"u}ll and Volkmar M{\"u}ller and Cordula Petersen and Isabell Witzel",
year = "2016",
month = jan,
day = "1",
doi = "10.1007/s00432-015-2049-4",
language = "English",
volume = "142",
pages = "325--32",
journal = "J CANCER RES CLIN",
issn = "0171-5216",
publisher = "Springer",
number = "1",

}

RIS

TY - JOUR

T1 - Comparison of nine prognostic scores in patients with brain metastases of breast cancer receiving radiotherapy of the brain

AU - Laakmann, Elena

AU - Riecke, Kerstin

AU - Goy, Yvonne

AU - Kersten, Jan F

AU - Krüll, Andreas

AU - Müller, Volkmar

AU - Petersen, Cordula

AU - Witzel, Isabell

PY - 2016/1/1

Y1 - 2016/1/1

N2 - PURPOSE: Several prognostic indices (PI) have been developed to stratify patients with brain metastases in groups with good or bad prognosis. The aim of our study was to compare nine prognostic scores for patients with brain metastases (BM) of breast cancer receiving radiotherapy.METHODS: The clinical data of 139 breast cancer patients with BM were collected retrospectively. All patients were treated with cerebral radiotherapy or surgery followed by radiotherapy between January 2007 and December 2012. The prognostic value and accuracy of recursive partitioning analysis (RPA), RPA II, graded prognostic assessment (GPA), basic score for BM, Breast-RPA, Breast-GPA, Rades Score 2011, Germany Score and Breast Rades Score were assessed.RESULTS: The median survival after BM diagnosis in our cohort was 14 months. The overall 6-month, 1-, 2- and 3-year survival rates were 49.6, 37.4, 20.9 and 13.7 %, respectively. Most of the PI were associated with OS, but univariate analysis favored GPA regarding OS. GPA was the most accurate score to identify patients with long (longer than 12 months) and Breast-GPA patients with short (<3 months) life expectancy.CONCLUSIONS: GPA and Breast-GPA seem to be the most useful scores and perform better than other PI for breast cancer patients with BM receiving radiotherapy.

AB - PURPOSE: Several prognostic indices (PI) have been developed to stratify patients with brain metastases in groups with good or bad prognosis. The aim of our study was to compare nine prognostic scores for patients with brain metastases (BM) of breast cancer receiving radiotherapy.METHODS: The clinical data of 139 breast cancer patients with BM were collected retrospectively. All patients were treated with cerebral radiotherapy or surgery followed by radiotherapy between January 2007 and December 2012. The prognostic value and accuracy of recursive partitioning analysis (RPA), RPA II, graded prognostic assessment (GPA), basic score for BM, Breast-RPA, Breast-GPA, Rades Score 2011, Germany Score and Breast Rades Score were assessed.RESULTS: The median survival after BM diagnosis in our cohort was 14 months. The overall 6-month, 1-, 2- and 3-year survival rates were 49.6, 37.4, 20.9 and 13.7 %, respectively. Most of the PI were associated with OS, but univariate analysis favored GPA regarding OS. GPA was the most accurate score to identify patients with long (longer than 12 months) and Breast-GPA patients with short (<3 months) life expectancy.CONCLUSIONS: GPA and Breast-GPA seem to be the most useful scores and perform better than other PI for breast cancer patients with BM receiving radiotherapy.

U2 - 10.1007/s00432-015-2049-4

DO - 10.1007/s00432-015-2049-4

M3 - SCORING: Journal article

C2 - 26424693

VL - 142

SP - 325

EP - 332

JO - J CANCER RES CLIN

JF - J CANCER RES CLIN

SN - 0171-5216

IS - 1

ER -