Comparison of image quality and visibility of normal and abnormal findings at submillisievert chest CT using filtered back projection, iterative model reconstruction (IMR) and iDose(4)™
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Comparison of image quality and visibility of normal and abnormal findings at submillisievert chest CT using filtered back projection, iterative model reconstruction (IMR) and iDose(4)™. / Laqmani, Azien; Avanesov, Maxim; Butscheidt, Sebastian; Kurfürst, Maximillian; Sehner, Susanne; Schmidt-Holtz, Jakob; Derlin, Thorsten; Behzadi, Cyrus; Nagel, Hans D; Adam, Gerhard; Regier, Marc.
In: EUR J RADIOL, Vol. 85, No. 11, 11.2016, p. 1971-1979.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
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TY - JOUR
T1 - Comparison of image quality and visibility of normal and abnormal findings at submillisievert chest CT using filtered back projection, iterative model reconstruction (IMR) and iDose(4)™
AU - Laqmani, Azien
AU - Avanesov, Maxim
AU - Butscheidt, Sebastian
AU - Kurfürst, Maximillian
AU - Sehner, Susanne
AU - Schmidt-Holtz, Jakob
AU - Derlin, Thorsten
AU - Behzadi, Cyrus
AU - Nagel, Hans D
AU - Adam, Gerhard
AU - Regier, Marc
N1 - Copyright © 2016 Elsevier Ireland Ltd. All rights reserved.
PY - 2016/11
Y1 - 2016/11
N2 - OBJECTIVE: To compare both image quality and visibility of normal and abnormal findings at submillisievert chest CT (smSv-CT) using filtered back projection (FBP) and the two different iterative reconstruction (IR) techniques iterative model reconstruction (IMR) and iDose(4)™.MATERIALS AND METHODS: This institutional review board approved study was based on retrospective interpretation of clinically indicated acquired data. The requirement to obtain informed consent was waived. 81 patients with suspected pneumonia underwent smSv-CT (Brilliance iCT, Philips Healthcare; mean effective dose: 0.86±0.2mSv). Data were reconstructed using FBP and two different IR techniques iDose(4)™ and IMR (Philips Healthcare) at various iteration levels. Objective image noise (OIN) was measured. Two experienced readers independently assessed all images for image noise, image appearance and visibility of normal anatomic and abnormal findings. A random intercept model was used for statistical analysis.RESULTS: Compared to FBP and iDose(4)™, IMR reduced OIN up to 88% and 72%, respectively (p<0.001). A mild blotchy image appearance was seen in IMR images, affecting diagnostic confidence. iDose(4)™ images provided satisfactory to good image quality for visibility of normal and abnormal findings and were superior to FBP (p<0.001). IMR images were significantly inferior for visibility of normal structures compared to iDose(4)™, while being superior for visibility of abnormal findings except for reticular pattern (p<0.001).CONCLUSION: IMR results for visibility of normal and abnormal lung findings are heterogeneous, indicating that IMR may not represent a priority technique for clinical routine. iDose(4)™ represents a suitable method for evaluation of lung tissue at submillisievert chest CT.
AB - OBJECTIVE: To compare both image quality and visibility of normal and abnormal findings at submillisievert chest CT (smSv-CT) using filtered back projection (FBP) and the two different iterative reconstruction (IR) techniques iterative model reconstruction (IMR) and iDose(4)™.MATERIALS AND METHODS: This institutional review board approved study was based on retrospective interpretation of clinically indicated acquired data. The requirement to obtain informed consent was waived. 81 patients with suspected pneumonia underwent smSv-CT (Brilliance iCT, Philips Healthcare; mean effective dose: 0.86±0.2mSv). Data were reconstructed using FBP and two different IR techniques iDose(4)™ and IMR (Philips Healthcare) at various iteration levels. Objective image noise (OIN) was measured. Two experienced readers independently assessed all images for image noise, image appearance and visibility of normal anatomic and abnormal findings. A random intercept model was used for statistical analysis.RESULTS: Compared to FBP and iDose(4)™, IMR reduced OIN up to 88% and 72%, respectively (p<0.001). A mild blotchy image appearance was seen in IMR images, affecting diagnostic confidence. iDose(4)™ images provided satisfactory to good image quality for visibility of normal and abnormal findings and were superior to FBP (p<0.001). IMR images were significantly inferior for visibility of normal structures compared to iDose(4)™, while being superior for visibility of abnormal findings except for reticular pattern (p<0.001).CONCLUSION: IMR results for visibility of normal and abnormal lung findings are heterogeneous, indicating that IMR may not represent a priority technique for clinical routine. iDose(4)™ represents a suitable method for evaluation of lung tissue at submillisievert chest CT.
KW - Female
KW - Humans
KW - Image Processing, Computer-Assisted
KW - Lung
KW - Male
KW - Middle Aged
KW - Pneumonia
KW - Prospective Studies
KW - Radiation Dosage
KW - Radiographic Image Interpretation, Computer-Assisted
KW - Reproducibility of Results
KW - Retrospective Studies
KW - Tomography, X-Ray Computed
KW - Comparative Study
KW - Journal Article
U2 - 10.1016/j.ejrad.2016.09.001
DO - 10.1016/j.ejrad.2016.09.001
M3 - SCORING: Journal article
C2 - 27776648
VL - 85
SP - 1971
EP - 1979
JO - EUR J RADIOL
JF - EUR J RADIOL
SN - 0720-048X
IS - 11
ER -