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Comparison of flow cytometry vs. a haematology cell analyser-based method to guide the optimal time-point for peripheral blood stem cell apheresis.

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Comparison of flow cytometry vs. a haematology cell analyser-based method to guide the optimal time-point for peripheral blood stem cell apheresis. / Gutensohn, K; Magens, M; Krüger, W; Kröger, Nicolaus; Kühnl, Peter.

In: VOX SANG, Vol. 90, No. 1, 1, 2006, p. 53-58.

Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

Harvard

Gutensohn, K, Magens, M, Krüger, W, Kröger, N & Kühnl, P 2006, 'Comparison of flow cytometry vs. a haematology cell analyser-based method to guide the optimal time-point for peripheral blood stem cell apheresis.', VOX SANG, vol. 90, no. 1, 1, pp. 53-58. <http://www.ncbi.nlm.nih.gov/pubmed/16359356?dopt=Citation>

APA

Gutensohn, K., Magens, M., Krüger, W., Kröger, N., & Kühnl, P. (2006). Comparison of flow cytometry vs. a haematology cell analyser-based method to guide the optimal time-point for peripheral blood stem cell apheresis. VOX SANG, 90(1), 53-58. [1]. http://www.ncbi.nlm.nih.gov/pubmed/16359356?dopt=Citation

Vancouver

Gutensohn K, Magens M, Krüger W, Kröger N, Kühnl P. Comparison of flow cytometry vs. a haematology cell analyser-based method to guide the optimal time-point for peripheral blood stem cell apheresis. VOX SANG. 2006;90(1):53-58. 1.

Bibtex

@article{f7628663ccb24137be26b1ab00419f55,
title = "Comparison of flow cytometry vs. a haematology cell analyser-based method to guide the optimal time-point for peripheral blood stem cell apheresis.",
abstract = "BACKGROUND AND OBJECTIVES: For timing the onset of apheresis, parameters obtained by flow cytometry and by a haematological cell analyser were compared. MATERIALS AND METHODS: Haematopoietic cell counts (n = 159) were performed by two different methods; CD34 analyses by flow cytometry, immature myeloid information (IMI) and human progenitor cell counts (HPC) by a haematological cell analyser. RESULTS: Comparing the IMI total results with CD34+ analyses (n = 159) revealed a correlation of r = 0.46 (P <0.05). Similar results were obtained for HPC (r = 0.44; P <0.05). CONCLUSION: The haematology analyser-based method does not allow the precise determination of absolute haematopoietic stem cell numbers and is thus not able to replace flow cytometry for the monitoring of peripheral blood stem cell counts.",
author = "K Gutensohn and M Magens and W Kr{\"u}ger and Nicolaus Kr{\"o}ger and Peter K{\"u}hnl",
year = "2006",
language = "Deutsch",
volume = "90",
pages = "53--58",
journal = "VOX SANG",
issn = "0042-9007",
publisher = "Wiley-Blackwell",
number = "1",

}

RIS

TY - JOUR

T1 - Comparison of flow cytometry vs. a haematology cell analyser-based method to guide the optimal time-point for peripheral blood stem cell apheresis.

AU - Gutensohn, K

AU - Magens, M

AU - Krüger, W

AU - Kröger, Nicolaus

AU - Kühnl, Peter

PY - 2006

Y1 - 2006

N2 - BACKGROUND AND OBJECTIVES: For timing the onset of apheresis, parameters obtained by flow cytometry and by a haematological cell analyser were compared. MATERIALS AND METHODS: Haematopoietic cell counts (n = 159) were performed by two different methods; CD34 analyses by flow cytometry, immature myeloid information (IMI) and human progenitor cell counts (HPC) by a haematological cell analyser. RESULTS: Comparing the IMI total results with CD34+ analyses (n = 159) revealed a correlation of r = 0.46 (P <0.05). Similar results were obtained for HPC (r = 0.44; P <0.05). CONCLUSION: The haematology analyser-based method does not allow the precise determination of absolute haematopoietic stem cell numbers and is thus not able to replace flow cytometry for the monitoring of peripheral blood stem cell counts.

AB - BACKGROUND AND OBJECTIVES: For timing the onset of apheresis, parameters obtained by flow cytometry and by a haematological cell analyser were compared. MATERIALS AND METHODS: Haematopoietic cell counts (n = 159) were performed by two different methods; CD34 analyses by flow cytometry, immature myeloid information (IMI) and human progenitor cell counts (HPC) by a haematological cell analyser. RESULTS: Comparing the IMI total results with CD34+ analyses (n = 159) revealed a correlation of r = 0.46 (P <0.05). Similar results were obtained for HPC (r = 0.44; P <0.05). CONCLUSION: The haematology analyser-based method does not allow the precise determination of absolute haematopoietic stem cell numbers and is thus not able to replace flow cytometry for the monitoring of peripheral blood stem cell counts.

M3 - SCORING: Zeitschriftenaufsatz

VL - 90

SP - 53

EP - 58

JO - VOX SANG

JF - VOX SANG

SN - 0042-9007

IS - 1

M1 - 1

ER -