Research ExplorerPublicationsComparison of complications from radical cystectomy between ...

Comparison of complications from radical cystectomy between old-old versus oldest-old patients

Standard

Comparison of complications from radical cystectomy between old-old versus oldest-old patients. / Comploj, Evi; West, Jeremy; Mian, Michael; Kluth, Luis Alex; Karl, Alexander; Dechet, Christopher; Shariat, Shahrokh F; Stief, Christian G; Trenti, Emanuela; Palermo, Salvatore; Lodde, Michele; Horninger, Wolfgang; Madersbacher, Stephan; Pycha, Armin.

In: UROL INT, Vol. 94, No. 1, 2015, p. 25-30.

Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

Harvard

Comploj, E, West, J, Mian, M, Kluth, LA, Karl, A, Dechet, C, Shariat, SF, Stief, CG, Trenti, E, Palermo, S, Lodde, M, Horninger, W, Madersbacher, S & Pycha, A 2015, 'Comparison of complications from radical cystectomy between old-old versus oldest-old patients', UROL INT, vol. 94, no. 1, pp. 25-30. https://doi.org/10.1159/000358731

APA

Comploj, E., West, J., Mian, M., Kluth, L. A., Karl, A., Dechet, C., Shariat, S. F., Stief, C. G., Trenti, E., Palermo, S., Lodde, M., Horninger, W., Madersbacher, S., & Pycha, A. (2015). Comparison of complications from radical cystectomy between old-old versus oldest-old patients. UROL INT, 94(1), 25-30. https://doi.org/10.1159/000358731

Vancouver

Comploj E, West J, Mian M, Kluth LA, Karl A, Dechet C et al. Comparison of complications from radical cystectomy between old-old versus oldest-old patients. UROL INT. 2015;94(1):25-30. https://doi.org/10.1159/000358731

Bibtex

@article{402e3a3d99f849ab99b002fadde5eb87,
title = "Comparison of complications from radical cystectomy between old-old versus oldest-old patients",
abstract = "INTRODUCTION: The purpose of this study was to evaluate and compare complications after radical cystectomy in patients aged ≥75 years.MATERIALS AND METHODS: 251 patients aged 75-95 years (median 79) underwent radical cystectomy between 2000 and 2012 at four institutions. The patients were divided into two groups: ≥75-84 years of age (group 1) versus ≥85 years of age (group 2). Comorbidities, body mass index, and complications were obtained retrospectively, except at the Central Hospital of Bolzano and Weill Cornell Medical Center, which collected data prospectively. Cancer-specific survival, overall mortality, hospital stay, clinical outcome and complications were assessed. Complications were categorized using the Clavien-Dindo classification reporting system. The mean follow-up was 21 months.RESULTS: The median hospital stay was 17 (2-91) days. Perioperative Clavien-Dindo grade ≥III complications were seen in 24.1% (48/199) of group 1 patients and 19.2% (10/52) of group 2 patients (p = 0.045). 30- and 90-day mortality was 4.5 and 13.5% in group 1 and 6.5 and 32.3% in group 2, respectively. Only the 90-day mortality rate was statistically significant (p < 0.05) between the two groups. The 3-year overall survival was 40% in group 1 and 34% in group 2. The 3-year cancer-specific survival was 52% in group 1 and 50% in group 2.CONCLUSIONS: We evaluated a large series of elderly (≥75 years) patients undergoing radical cystectomy at four institutions. Comparing patients aged ≥75-84 and ≥85 years revealed no significant difference in complications, 30-day mortality, overall and cancer-specific survival rates. Only 90-day mortality rates were significantly higher in the ≥85-year-old patients.",
keywords = "Age Factors, Aged, Aged, 80 and over, Body Mass Index, Comorbidity, Cystectomy, Disease Progression, Disease-Free Survival, Europe, Female, Humans, Kaplan-Meier Estimate, Length of Stay, Male, Postoperative Complications, Prospective Studies, Retrospective Studies, Risk Factors, Time Factors, Treatment Outcome, Urinary Bladder Neoplasms",
author = "Evi Comploj and Jeremy West and Michael Mian and Kluth, {Luis Alex} and Alexander Karl and Christopher Dechet and Shariat, {Shahrokh F} and Stief, {Christian G} and Emanuela Trenti and Salvatore Palermo and Michele Lodde and Wolfgang Horninger and Stephan Madersbacher and Armin Pycha",
note = "{\textcopyright} 2014 S. Karger AG, Basel.",
year = "2015",
doi = "10.1159/000358731",
language = "English",
volume = "94",
pages = "25--30",
journal = "UROL INT",
issn = "0042-1138",
publisher = "S. Karger AG",
number = "1",

}

RIS

TY - JOUR

T1 - Comparison of complications from radical cystectomy between old-old versus oldest-old patients

AU - Comploj, Evi

AU - West, Jeremy

AU - Mian, Michael

AU - Kluth, Luis Alex

AU - Karl, Alexander

AU - Dechet, Christopher

AU - Shariat, Shahrokh F

AU - Stief, Christian G

AU - Trenti, Emanuela

AU - Palermo, Salvatore

AU - Lodde, Michele

AU - Horninger, Wolfgang

AU - Madersbacher, Stephan

AU - Pycha, Armin

N1 - © 2014 S. Karger AG, Basel.

PY - 2015

Y1 - 2015

N2 - INTRODUCTION: The purpose of this study was to evaluate and compare complications after radical cystectomy in patients aged ≥75 years.MATERIALS AND METHODS: 251 patients aged 75-95 years (median 79) underwent radical cystectomy between 2000 and 2012 at four institutions. The patients were divided into two groups: ≥75-84 years of age (group 1) versus ≥85 years of age (group 2). Comorbidities, body mass index, and complications were obtained retrospectively, except at the Central Hospital of Bolzano and Weill Cornell Medical Center, which collected data prospectively. Cancer-specific survival, overall mortality, hospital stay, clinical outcome and complications were assessed. Complications were categorized using the Clavien-Dindo classification reporting system. The mean follow-up was 21 months.RESULTS: The median hospital stay was 17 (2-91) days. Perioperative Clavien-Dindo grade ≥III complications were seen in 24.1% (48/199) of group 1 patients and 19.2% (10/52) of group 2 patients (p = 0.045). 30- and 90-day mortality was 4.5 and 13.5% in group 1 and 6.5 and 32.3% in group 2, respectively. Only the 90-day mortality rate was statistically significant (p < 0.05) between the two groups. The 3-year overall survival was 40% in group 1 and 34% in group 2. The 3-year cancer-specific survival was 52% in group 1 and 50% in group 2.CONCLUSIONS: We evaluated a large series of elderly (≥75 years) patients undergoing radical cystectomy at four institutions. Comparing patients aged ≥75-84 and ≥85 years revealed no significant difference in complications, 30-day mortality, overall and cancer-specific survival rates. Only 90-day mortality rates were significantly higher in the ≥85-year-old patients.

AB - INTRODUCTION: The purpose of this study was to evaluate and compare complications after radical cystectomy in patients aged ≥75 years.MATERIALS AND METHODS: 251 patients aged 75-95 years (median 79) underwent radical cystectomy between 2000 and 2012 at four institutions. The patients were divided into two groups: ≥75-84 years of age (group 1) versus ≥85 years of age (group 2). Comorbidities, body mass index, and complications were obtained retrospectively, except at the Central Hospital of Bolzano and Weill Cornell Medical Center, which collected data prospectively. Cancer-specific survival, overall mortality, hospital stay, clinical outcome and complications were assessed. Complications were categorized using the Clavien-Dindo classification reporting system. The mean follow-up was 21 months.RESULTS: The median hospital stay was 17 (2-91) days. Perioperative Clavien-Dindo grade ≥III complications were seen in 24.1% (48/199) of group 1 patients and 19.2% (10/52) of group 2 patients (p = 0.045). 30- and 90-day mortality was 4.5 and 13.5% in group 1 and 6.5 and 32.3% in group 2, respectively. Only the 90-day mortality rate was statistically significant (p < 0.05) between the two groups. The 3-year overall survival was 40% in group 1 and 34% in group 2. The 3-year cancer-specific survival was 52% in group 1 and 50% in group 2.CONCLUSIONS: We evaluated a large series of elderly (≥75 years) patients undergoing radical cystectomy at four institutions. Comparing patients aged ≥75-84 and ≥85 years revealed no significant difference in complications, 30-day mortality, overall and cancer-specific survival rates. Only 90-day mortality rates were significantly higher in the ≥85-year-old patients.

KW - Age Factors

KW - Aged

KW - Aged, 80 and over

KW - Body Mass Index

KW - Comorbidity

KW - Cystectomy

KW - Disease Progression

KW - Disease-Free Survival

KW - Europe

KW - Female

KW - Humans

KW - Kaplan-Meier Estimate

KW - Length of Stay

KW - Male

KW - Postoperative Complications

KW - Prospective Studies

KW - Retrospective Studies

KW - Risk Factors

KW - Time Factors

KW - Treatment Outcome

KW - Urinary Bladder Neoplasms

U2 - 10.1159/000358731

DO - 10.1159/000358731

M3 - SCORING: Journal article

C2 - 24969739

VL - 94

SP - 25

EP - 30

JO - UROL INT

JF - UROL INT

SN - 0042-1138

IS - 1

ER -