Research ExplorerPublicationsComparison of 4 proliferation markers and their significance...

Comparison of 4 proliferation markers and their significance for evaluation of tumor dignity in intracranial tumors

Standard

Comparison of 4 proliferation markers and their significance for evaluation of tumor dignity in intracranial tumors. / Hagel, C; Schwartz, P; Laas, R; Stavrou, D.

In: INT J ONCOL, Vol. 7, No. 1, 01.07.1995, p. 107-13.

Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

Harvard

Hagel, C, Schwartz, P, Laas, R & Stavrou, D 1995, 'Comparison of 4 proliferation markers and their significance for evaluation of tumor dignity in intracranial tumors', INT J ONCOL, vol. 7, no. 1, pp. 107-13.

APA

Hagel, C., Schwartz, P., Laas, R., & Stavrou, D. (1995). Comparison of 4 proliferation markers and their significance for evaluation of tumor dignity in intracranial tumors. INT J ONCOL, 7(1), 107-13.

Vancouver

Hagel C, Schwartz P, Laas R, Stavrou D. Comparison of 4 proliferation markers and their significance for evaluation of tumor dignity in intracranial tumors. INT J ONCOL. 1995 Jul 1;7(1):107-13.

Bibtex

@article{84509e946a814247aaf1399c27106daf,
title = "Comparison of 4 proliferation markers and their significance for evaluation of tumor dignity in intracranial tumors",
abstract = "The proliferation indices of immunohistochemically detected bromodeoxyuridine, Ki-67 antigen (antibodies Ki-67 and MIB 1), and proliferating cell nuclear antigen were determined manually and with computer assisted morphometry in 38 gliomas, 29 meningeomas, 9 metastases, and 16 other tumors. Comparing the markers among one another the highest correlation coefficient was found for bromodeoxyuridine and MIB 1 (0.9). The proliferation indices of all markers correlated significantly with the tumor grading. The highest correlation coefficient for proliferation index and grading (0.7) was calculated for the MIB 1 index determined in one high power field (0.0153 mm(2)) in the tissue area with the highest proliferative activity. Concerning applicability and correlation with tumor dignity MIB 1 was superior to the other three antibodies investigated.",
author = "C Hagel and P Schwartz and R Laas and D Stavrou",
year = "1995",
month = jul,
day = "1",
language = "English",
volume = "7",
pages = "107--13",
journal = "INT J ONCOL",
issn = "1019-6439",
publisher = "Spandidos Publications",
number = "1",

}

RIS

TY - JOUR

T1 - Comparison of 4 proliferation markers and their significance for evaluation of tumor dignity in intracranial tumors

AU - Hagel, C

AU - Schwartz, P

AU - Laas, R

AU - Stavrou, D

PY - 1995/7/1

Y1 - 1995/7/1

N2 - The proliferation indices of immunohistochemically detected bromodeoxyuridine, Ki-67 antigen (antibodies Ki-67 and MIB 1), and proliferating cell nuclear antigen were determined manually and with computer assisted morphometry in 38 gliomas, 29 meningeomas, 9 metastases, and 16 other tumors. Comparing the markers among one another the highest correlation coefficient was found for bromodeoxyuridine and MIB 1 (0.9). The proliferation indices of all markers correlated significantly with the tumor grading. The highest correlation coefficient for proliferation index and grading (0.7) was calculated for the MIB 1 index determined in one high power field (0.0153 mm(2)) in the tissue area with the highest proliferative activity. Concerning applicability and correlation with tumor dignity MIB 1 was superior to the other three antibodies investigated.

AB - The proliferation indices of immunohistochemically detected bromodeoxyuridine, Ki-67 antigen (antibodies Ki-67 and MIB 1), and proliferating cell nuclear antigen were determined manually and with computer assisted morphometry in 38 gliomas, 29 meningeomas, 9 metastases, and 16 other tumors. Comparing the markers among one another the highest correlation coefficient was found for bromodeoxyuridine and MIB 1 (0.9). The proliferation indices of all markers correlated significantly with the tumor grading. The highest correlation coefficient for proliferation index and grading (0.7) was calculated for the MIB 1 index determined in one high power field (0.0153 mm(2)) in the tissue area with the highest proliferative activity. Concerning applicability and correlation with tumor dignity MIB 1 was superior to the other three antibodies investigated.

M3 - SCORING: Journal article

C2 - 21552814

VL - 7

SP - 107

EP - 113

JO - INT J ONCOL

JF - INT J ONCOL

SN - 1019-6439

IS - 1

ER -