Combination chemotherapy and radiotherapy for Hodgkin's disease in children.
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Combination chemotherapy and radiotherapy for Hodgkin's disease in children. / Janka-Schaub, Gritta; Lau, B M; Haas, R J; von Lieven, H P; Lampert, F.
In: EUR J PEDIATR, Vol. 127, No. 4, 4, 1978, p. 287-292.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
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T1 - Combination chemotherapy and radiotherapy for Hodgkin's disease in children.
AU - Janka-Schaub, Gritta
AU - Lau, B M
AU - Haas, R J
AU - von Lieven, H P
AU - Lampert, F
PY - 1978
Y1 - 1978
N2 - 31 children with Hodgkin's disease were treated at the Children's Hospital, University of Munich, between 1963-1976. Before 1971 the diagnosis of abdominal involvement was based solely on physical findings and radiological studies. Treatment consisted of involved-field radiation; chemotherapy was added in selected cases. Of 15 children treated between 1963-1971, 5 are still in their first remission and 2 in their second remission. Since 1971 exploratory laparotomy and splenectomy have been performed. Radiation therapy was changed from involved- to extended-field therapy and combination chemotherapy was added in all the children. No patient from this group of 16 children relapsed during a median observation time of 24 months (range 12-55 months). The toxicity of the combined treatment does not seem to be prohibitive.
AB - 31 children with Hodgkin's disease were treated at the Children's Hospital, University of Munich, between 1963-1976. Before 1971 the diagnosis of abdominal involvement was based solely on physical findings and radiological studies. Treatment consisted of involved-field radiation; chemotherapy was added in selected cases. Of 15 children treated between 1963-1971, 5 are still in their first remission and 2 in their second remission. Since 1971 exploratory laparotomy and splenectomy have been performed. Radiation therapy was changed from involved- to extended-field therapy and combination chemotherapy was added in all the children. No patient from this group of 16 children relapsed during a median observation time of 24 months (range 12-55 months). The toxicity of the combined treatment does not seem to be prohibitive.
M3 - SCORING: Zeitschriftenaufsatz
VL - 127
SP - 287
EP - 292
JO - EUR J PEDIATR
JF - EUR J PEDIATR
SN - 0340-6199
IS - 4
M1 - 4
ER -
