Coma blisters in a case of fatal theophylline intoxication.
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Coma blisters in a case of fatal theophylline intoxication. / Tsokos, Michael; Sperhake, Jan.
In: AM J FOREN MED PATH, Vol. 23, No. 3, 3, 2002, p. 292-294.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
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TY - JOUR
T1 - Coma blisters in a case of fatal theophylline intoxication.
AU - Tsokos, Michael
AU - Sperhake, Jan
PY - 2002
Y1 - 2002
N2 - A case of fatal poisoning caused by theophylline toxicity (serum level 127 micro g/ml) is presented. At external examination, skin blisters on regions exposed to pressure were distinctive. Histologic examination demonstrated subepidermal bullae with eosinophilic necrosis of the eccrine sweat gland coil but no epidermal necrosis, vascular changes, or inflammatory infiltrate. To the authors' knowledge, this is the first description of coma blisters in a case of theophylline intoxication.
AB - A case of fatal poisoning caused by theophylline toxicity (serum level 127 micro g/ml) is presented. At external examination, skin blisters on regions exposed to pressure were distinctive. Histologic examination demonstrated subepidermal bullae with eosinophilic necrosis of the eccrine sweat gland coil but no epidermal necrosis, vascular changes, or inflammatory infiltrate. To the authors' knowledge, this is the first description of coma blisters in a case of theophylline intoxication.
M3 - SCORING: Zeitschriftenaufsatz
VL - 23
SP - 292
EP - 294
JO - AM J FOREN MED PATH
JF - AM J FOREN MED PATH
SN - 0195-7910
IS - 3
M1 - 3
ER -