Cohort profile: the ESC EURObservational Research Programme Atrial Fibrillation III (AF III) Registry

TY - JOUR

T1 - Cohort profile: the ESC EURObservational Research Programme Atrial Fibrillation III (AF III) Registry

AU - Potpara, Tatjana S

AU - Lip, Gregory Y H

AU - Dagres, Nikolaos

AU - Crijns, Harry J M G

AU - Boriani, Giuseppe

AU - Kirchhof, Paulus

AU - Arbelo, Elena

AU - Savelieva, Irina

AU - Lenarczyk, Radoslaw

AU - Fauchier, Laurent

AU - Maggioni, Aldo P

AU - Gale, Chris P

AU - EORP-AF III Investigators Group

N1 - Published on behalf of the European Society of Cardiology. All rights reserved. © The Author(s) 2020. For permissions, please email: journals.permissions@oup.com.

PY - 2021/5/3

Y1 - 2021/5/3

N2 - AIMS: The European Society of Cardiology (ESC) EURObservational Research Programme (EORP)-Atrial Fibrillation (AF) III Registry aims to identify contemporary patterns in AF management in clinical practice, assess their compliance with the 2016 ESC AF Guidelines, identify major gaps in guideline implementation, characterize the clinical practice settings associated with good vs. poor guideline implementation and assess and compare the 1-year outcome of guideline-adherent vs. guideline non-adherent management strategies.METHODS AND RESULTS: Consecutive adult AF patients (n = 8306) were enrolled between 1 July 2018 and 15 July 2019, and individual patient data were prospectively collected across 192 centres and 31 participating countries during the 3-month enrolment period per centre. The Registry collected baseline and 1-year follow-up data in the eight main domains: patient demographic/enrolment setting, AF diagnosis/characterization, diagnostic assessment, stroke prevention treatments, arrhythmia-directed therapies, integrated AF management, major outcomes (death, non-fatal stroke or systemic embolic event, and non-fatal bleeding event), and the quality of life questionnaire.CONCLUSION: The EORP-AF III Registry is an international, prospective registry of care and outcomes of patients treated for AF, which will provide insights into the contemporary patterns in AF management, ESC AF Guidelines implementation in routine practice and barriers to optimal management of this highly prevalent arrhythmia.

AB - AIMS: The European Society of Cardiology (ESC) EURObservational Research Programme (EORP)-Atrial Fibrillation (AF) III Registry aims to identify contemporary patterns in AF management in clinical practice, assess their compliance with the 2016 ESC AF Guidelines, identify major gaps in guideline implementation, characterize the clinical practice settings associated with good vs. poor guideline implementation and assess and compare the 1-year outcome of guideline-adherent vs. guideline non-adherent management strategies.METHODS AND RESULTS: Consecutive adult AF patients (n = 8306) were enrolled between 1 July 2018 and 15 July 2019, and individual patient data were prospectively collected across 192 centres and 31 participating countries during the 3-month enrolment period per centre. The Registry collected baseline and 1-year follow-up data in the eight main domains: patient demographic/enrolment setting, AF diagnosis/characterization, diagnostic assessment, stroke prevention treatments, arrhythmia-directed therapies, integrated AF management, major outcomes (death, non-fatal stroke or systemic embolic event, and non-fatal bleeding event), and the quality of life questionnaire.CONCLUSION: The EORP-AF III Registry is an international, prospective registry of care and outcomes of patients treated for AF, which will provide insights into the contemporary patterns in AF management, ESC AF Guidelines implementation in routine practice and barriers to optimal management of this highly prevalent arrhythmia.

U2 - 10.1093/ehjqcco/qcaa050

DO - 10.1093/ehjqcco/qcaa050

M3 - SCORING: Journal article

C2 - 32514547

VL - 7

SP - 229

EP - 237

JO - EUR HEART J-QUAL CAR

JF - EUR HEART J-QUAL CAR

SN - 2058-5225

IS - 3

ER -