Cognitive dysfunction at baseline predicts symptomatic 1-year outcome in first-episode schizophrenics.
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Cognitive dysfunction at baseline predicts symptomatic 1-year outcome in first-episode schizophrenics. / Moritz, Steffen; Krausz, M; Gottwalz, E; Lambert, Martin; Perro, C; Ganzer, S; Naber, Dieter.
In: PSYCHOPATHOLOGY, Vol. 33, No. 1, 1, 2000, p. 48-51.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
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TY - JOUR
T1 - Cognitive dysfunction at baseline predicts symptomatic 1-year outcome in first-episode schizophrenics.
AU - Moritz, Steffen
AU - Krausz, M
AU - Gottwalz, E
AU - Lambert, Martin
AU - Perro, C
AU - Ganzer, S
AU - Naber, Dieter
PY - 2000
Y1 - 2000
N2 - The present study addresses the consequences of cognitive disturbances on symptomatic outcome. Fifty-three first-episode schizophrenics were reassessed (n = 32) 1 year after admission. Simple regression analyses revealed that several self-perceived cognitive deficits at baseline as measured with the Frankfurt Complaint Questionnaire significantly predicted increased Brief Psychiatric Rating Scale global scores at follow-up (p = 0.05 to p = 0.005). A stepwise regression analysis proved memory dysfunction to be the strongest predictor of symptomatic worsening (p = 0.005). It is suggested that the exploration and treatment of neuropsychological deficits in schizophrenia is of great clinical importance with regard to its impact on both functional and symptomatic outcome in schizophrenia.
AB - The present study addresses the consequences of cognitive disturbances on symptomatic outcome. Fifty-three first-episode schizophrenics were reassessed (n = 32) 1 year after admission. Simple regression analyses revealed that several self-perceived cognitive deficits at baseline as measured with the Frankfurt Complaint Questionnaire significantly predicted increased Brief Psychiatric Rating Scale global scores at follow-up (p = 0.05 to p = 0.005). A stepwise regression analysis proved memory dysfunction to be the strongest predictor of symptomatic worsening (p = 0.005). It is suggested that the exploration and treatment of neuropsychological deficits in schizophrenia is of great clinical importance with regard to its impact on both functional and symptomatic outcome in schizophrenia.
M3 - SCORING: Zeitschriftenaufsatz
VL - 33
SP - 48
EP - 51
JO - PSYCHOPATHOLOGY
JF - PSYCHOPATHOLOGY
SN - 0254-4962
IS - 1
M1 - 1
ER -