Cof a 1: identification, expression and immunoreactivity of the first coffee allergen.
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Cof a 1: identification, expression and immunoreactivity of the first coffee allergen. / Manavski, Nikolay; Peters, Ulrike; Brettschneider, Reinhold; Oldenburg, Marcus; Baur, Xaver; Bittner, Cordula.
In: INT ARCH ALLERGY IMM, Vol. 159, No. 3, 3, 2012, p. 235-242.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
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TY - JOUR
T1 - Cof a 1: identification, expression and immunoreactivity of the first coffee allergen.
AU - Manavski, Nikolay
AU - Peters, Ulrike
AU - Brettschneider, Reinhold
AU - Oldenburg, Marcus
AU - Baur, Xaver
AU - Bittner, Cordula
PY - 2012
Y1 - 2012
N2 - Over the past years, dust of green coffee beans has become known to be a relevant cause for occupational type I allergies. Up to now, allergy diagnostics is based on native green coffee bean extract which exhibits insufficient specificity due to interfering substances as well as batch-to-batch variations. No coffee allergen has been described on the molecular level so far. The aim of this study was to identify the first allergen of green coffee.
AB - Over the past years, dust of green coffee beans has become known to be a relevant cause for occupational type I allergies. Up to now, allergy diagnostics is based on native green coffee bean extract which exhibits insufficient specificity due to interfering substances as well as batch-to-batch variations. No coffee allergen has been described on the molecular level so far. The aim of this study was to identify the first allergen of green coffee.
KW - Adult
KW - Humans
KW - Male
KW - Middle Aged
KW - Amino Acid Sequence
KW - Molecular Sequence Data
KW - Base Sequence
KW - Gene Expression
KW - Enzyme-Linked Immunosorbent Assay
KW - Cloning, Molecular
KW - Gene Library
KW - Escherichia coli/genetics
KW - Immunoglobulin E/blood/immunology
KW - Cell Surface Display Techniques
KW - Allergens/chemistry/genetics/immunology
KW - Chitinase/chemistry/genetics/immunology
KW - Coffea/adverse effects/immunology
KW - Dust/immunology
KW - Occupational Diseases/blood/etiology/immunology
KW - Plant Proteins/chemistry/genetics/immunology
KW - Recombinant Proteins/chemistry/genetics/immunology
KW - Respiratory Hypersensitivity/blood/etiology/immunology
KW - Adult
KW - Humans
KW - Male
KW - Middle Aged
KW - Amino Acid Sequence
KW - Molecular Sequence Data
KW - Base Sequence
KW - Gene Expression
KW - Enzyme-Linked Immunosorbent Assay
KW - Cloning, Molecular
KW - Gene Library
KW - Escherichia coli/genetics
KW - Immunoglobulin E/blood/immunology
KW - Cell Surface Display Techniques
KW - Allergens/chemistry/genetics/immunology
KW - Chitinase/chemistry/genetics/immunology
KW - Coffea/adverse effects/immunology
KW - Dust/immunology
KW - Occupational Diseases/blood/etiology/immunology
KW - Plant Proteins/chemistry/genetics/immunology
KW - Recombinant Proteins/chemistry/genetics/immunology
KW - Respiratory Hypersensitivity/blood/etiology/immunology
M3 - SCORING: Journal article
VL - 159
SP - 235
EP - 242
JO - INT ARCH ALLERGY IMM
JF - INT ARCH ALLERGY IMM
SN - 1018-2438
IS - 3
M1 - 3
ER -