Clinical Relevance of Circulating, Cell-Free and Exosomal microRNAs in Plasma and Serum of Breast Cancer Patients

Heidi Schwarzenbach

doi:10.1159/000478019

Clinical Relevance of Circulating, Cell-Free and Exosomal microRNAs in Plasma and Serum of Breast Cancer Patients

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Clinical Relevance of Circulating, Cell-Free and Exosomal microRNAs in Plasma and Serum of Breast Cancer Patients. / Schwarzenbach, Heidi.

In: ONCOL RES TREAT, Vol. 40, No. 7-8, 2017, p. 423-429.

Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

Harvard

Schwarzenbach, H 2017, 'Clinical Relevance of Circulating, Cell-Free and Exosomal microRNAs in Plasma and Serum of Breast Cancer Patients', ONCOL RES TREAT, vol. 40, no. 7-8, pp. 423-429. https://doi.org/10.1159/000478019

APA

Schwarzenbach, H. (2017). Clinical Relevance of Circulating, Cell-Free and Exosomal microRNAs in Plasma and Serum of Breast Cancer Patients. ONCOL RES TREAT, 40(7-8), 423-429. https://doi.org/10.1159/000478019

Vancouver

Schwarzenbach H. Clinical Relevance of Circulating, Cell-Free and Exosomal microRNAs in Plasma and Serum of Breast Cancer Patients. ONCOL RES TREAT. 2017;40(7-8):423-429. https://doi.org/10.1159/000478019

Bibtex

@article{486663aafe33439ea1f1c932667f574b,

title = "Clinical Relevance of Circulating, Cell-Free and Exosomal microRNAs in Plasma and Serum of Breast Cancer Patients",

abstract = "The expression of microRNAs (miRNAs) in a tissue- and development-specific manner has indicated that they play an essential role in the maintenance of biological homeostasis. In cancer, the deregulation of these small non-coding RNA molecules modulates the expression of numerous tumor-associated genes and cellular processes. The high levels of cancer-associated sensitivity and specificity of plasma/serum and exosomal miRNA profiles reflect disease development, tumor load, malignant progression towards metastatic relapse and drug resistance. The present review focuses on the findings related to the expression and function of miRNAs in breast cancer, and discusses the potential clinical uses of miRNAs, including their roles as therapeutic targets and diagnostic markers.",

keywords = "Journal Article",

author = "Heidi Schwarzenbach",

note = "{\textcopyright} 2017 S. Karger GmbH, Freiburg.",

year = "2017",

doi = "10.1159/000478019",

language = "English",

volume = "40",

pages = "423--429",

journal = "ONCOL RES TREAT",

issn = "2296-5270",

publisher = "S. Karger AG",

number = "7-8",

}

RIS

TY - JOUR

T1 - Clinical Relevance of Circulating, Cell-Free and Exosomal microRNAs in Plasma and Serum of Breast Cancer Patients

AU - Schwarzenbach, Heidi

PY - 2017

Y1 - 2017

N2 - The expression of microRNAs (miRNAs) in a tissue- and development-specific manner has indicated that they play an essential role in the maintenance of biological homeostasis. In cancer, the deregulation of these small non-coding RNA molecules modulates the expression of numerous tumor-associated genes and cellular processes. The high levels of cancer-associated sensitivity and specificity of plasma/serum and exosomal miRNA profiles reflect disease development, tumor load, malignant progression towards metastatic relapse and drug resistance. The present review focuses on the findings related to the expression and function of miRNAs in breast cancer, and discusses the potential clinical uses of miRNAs, including their roles as therapeutic targets and diagnostic markers.

AB - The expression of microRNAs (miRNAs) in a tissue- and development-specific manner has indicated that they play an essential role in the maintenance of biological homeostasis. In cancer, the deregulation of these small non-coding RNA molecules modulates the expression of numerous tumor-associated genes and cellular processes. The high levels of cancer-associated sensitivity and specificity of plasma/serum and exosomal miRNA profiles reflect disease development, tumor load, malignant progression towards metastatic relapse and drug resistance. The present review focuses on the findings related to the expression and function of miRNAs in breast cancer, and discusses the potential clinical uses of miRNAs, including their roles as therapeutic targets and diagnostic markers.

KW - Journal Article

U2 - 10.1159/000478019

DO - 10.1159/000478019

M3 - SCORING: Journal article

C2 - 28683441

VL - 40

SP - 423

EP - 429

JO - ONCOL RES TREAT

JF - ONCOL RES TREAT

SN - 2296-5270

IS - 7-8

ER -