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Clinical experience of combined HeartWare ventricular assist device and implantable cardioverter defibrillator therapy

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Clinical experience of combined HeartWare ventricular assist device and implantable cardioverter defibrillator therapy. / Pecha, Simon; Wilke, Iris; Bernhardt, Alexander; Hakmi, Samer; Yildirim, Yalin; Steven, Daniel; Reichenspurner, Hermann; Willems, Stephan; Deuse, Tobias; Aydin, Ali.

In: J CARDIOVASC ELECTR, Vol. 25, No. 10, 10.2014, p. 1109-1114.

Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

Harvard

Pecha, S, Wilke, I, Bernhardt, A, Hakmi, S, Yildirim, Y, Steven, D, Reichenspurner, H, Willems, S, Deuse, T & Aydin, A 2014, 'Clinical experience of combined HeartWare ventricular assist device and implantable cardioverter defibrillator therapy', J CARDIOVASC ELECTR, vol. 25, no. 10, pp. 1109-1114. https://doi.org/10.1111/jce.12455

APA

Pecha, S., Wilke, I., Bernhardt, A., Hakmi, S., Yildirim, Y., Steven, D., Reichenspurner, H., Willems, S., Deuse, T., & Aydin, A. (2014). Clinical experience of combined HeartWare ventricular assist device and implantable cardioverter defibrillator therapy. J CARDIOVASC ELECTR, 25(10), 1109-1114. https://doi.org/10.1111/jce.12455

Vancouver

Pecha S, Wilke I, Bernhardt A, Hakmi S, Yildirim Y, Steven D et al. Clinical experience of combined HeartWare ventricular assist device and implantable cardioverter defibrillator therapy. J CARDIOVASC ELECTR. 2014 Oct;25(10):1109-1114. https://doi.org/10.1111/jce.12455

Bibtex

@article{f399b6b321c04c6897004410de78ac7c,
title = "Clinical experience of combined HeartWare ventricular assist device and implantable cardioverter defibrillator therapy",
abstract = "INTRODUCTION: The HeartWare continuous flow ventricular assist device (HVAD) is used in an increasing number of heart failure patients. In those patients, ventricular arrhythmias (VAs) are common and, consequently, many patients already have an implanted implantable cardioverter defibrillator (ICD) in place or receive ICD implantation after left ventricular assist device implantation. However, limited data on feasibility and necessity of combined ICD and HVAD therapy are available. In this study we present our technical and clinical experience.METHODS AND RESULTS: Between 01/2010 and 06/2013, 41 patients received HVAD implantation. Twenty-six HVAD patients who already had an ICD device placed prior to HVAD implantation or received ICD implantation afterwards were enrolled in this study. Peri- and postoperative complications as well as ICD interrogations were documented and analyzed retrospectively. Mean patients age was 58.4 ± 12.6 years; 88.5% of patients were male. During mean follow-up of 12.2 ± 8.9 months, appropriate ICD interventions occurred in 9 patients (34.6%) due to ventricular tachyarrhythmia (n = 7) or ventricular fibrillation (n = 2). An inappropriate ICD intervention was seen in 1 patient (3.9%) due to tachycardic atrial fibrillation. Patients on HVAD with a history of VAs (n = 13) had a significantly higher incidence of ICD interventions compared to patients with primary prophylactic indication for ICD (n = 13; 53.8% vs. 7.7%; P = 0.015). No disturbance of ICD function was seen after HVAD implantation.CONCLUSION: Combined ICD and HVAD therapy was safe and feasible, without electromagnetic interference between ICD and ventricular assist device. The incidence of ICD interventions was high in patients with a history of VAs, but low in patients with ICD implantation for primary prevention.",
keywords = "Combined Modality Therapy/instrumentation, Defibrillators, Implantable, Equipment Design, Equipment Failure Analysis, Female, Heart Failure/diagnosis, Heart-Assist Devices, Humans, Male, Middle Aged, Treatment Outcome",
author = "Simon Pecha and Iris Wilke and Alexander Bernhardt and Samer Hakmi and Yalin Yildirim and Daniel Steven and Hermann Reichenspurner and Stephan Willems and Tobias Deuse and Ali Aydin",
note = "{\textcopyright} 2014 Wiley Periodicals, Inc.",
year = "2014",
month = oct,
doi = "10.1111/jce.12455",
language = "English",
volume = "25",
pages = "1109--1114",
journal = "J CARDIOVASC ELECTR",
issn = "1045-3873",
publisher = "Wiley-Blackwell",
number = "10",

}

RIS

TY - JOUR

T1 - Clinical experience of combined HeartWare ventricular assist device and implantable cardioverter defibrillator therapy

AU - Pecha, Simon

AU - Wilke, Iris

AU - Bernhardt, Alexander

AU - Hakmi, Samer

AU - Yildirim, Yalin

AU - Steven, Daniel

AU - Reichenspurner, Hermann

AU - Willems, Stephan

AU - Deuse, Tobias

AU - Aydin, Ali

N1 - © 2014 Wiley Periodicals, Inc.

PY - 2014/10

Y1 - 2014/10

N2 - INTRODUCTION: The HeartWare continuous flow ventricular assist device (HVAD) is used in an increasing number of heart failure patients. In those patients, ventricular arrhythmias (VAs) are common and, consequently, many patients already have an implanted implantable cardioverter defibrillator (ICD) in place or receive ICD implantation after left ventricular assist device implantation. However, limited data on feasibility and necessity of combined ICD and HVAD therapy are available. In this study we present our technical and clinical experience.METHODS AND RESULTS: Between 01/2010 and 06/2013, 41 patients received HVAD implantation. Twenty-six HVAD patients who already had an ICD device placed prior to HVAD implantation or received ICD implantation afterwards were enrolled in this study. Peri- and postoperative complications as well as ICD interrogations were documented and analyzed retrospectively. Mean patients age was 58.4 ± 12.6 years; 88.5% of patients were male. During mean follow-up of 12.2 ± 8.9 months, appropriate ICD interventions occurred in 9 patients (34.6%) due to ventricular tachyarrhythmia (n = 7) or ventricular fibrillation (n = 2). An inappropriate ICD intervention was seen in 1 patient (3.9%) due to tachycardic atrial fibrillation. Patients on HVAD with a history of VAs (n = 13) had a significantly higher incidence of ICD interventions compared to patients with primary prophylactic indication for ICD (n = 13; 53.8% vs. 7.7%; P = 0.015). No disturbance of ICD function was seen after HVAD implantation.CONCLUSION: Combined ICD and HVAD therapy was safe and feasible, without electromagnetic interference between ICD and ventricular assist device. The incidence of ICD interventions was high in patients with a history of VAs, but low in patients with ICD implantation for primary prevention.

AB - INTRODUCTION: The HeartWare continuous flow ventricular assist device (HVAD) is used in an increasing number of heart failure patients. In those patients, ventricular arrhythmias (VAs) are common and, consequently, many patients already have an implanted implantable cardioverter defibrillator (ICD) in place or receive ICD implantation after left ventricular assist device implantation. However, limited data on feasibility and necessity of combined ICD and HVAD therapy are available. In this study we present our technical and clinical experience.METHODS AND RESULTS: Between 01/2010 and 06/2013, 41 patients received HVAD implantation. Twenty-six HVAD patients who already had an ICD device placed prior to HVAD implantation or received ICD implantation afterwards were enrolled in this study. Peri- and postoperative complications as well as ICD interrogations were documented and analyzed retrospectively. Mean patients age was 58.4 ± 12.6 years; 88.5% of patients were male. During mean follow-up of 12.2 ± 8.9 months, appropriate ICD interventions occurred in 9 patients (34.6%) due to ventricular tachyarrhythmia (n = 7) or ventricular fibrillation (n = 2). An inappropriate ICD intervention was seen in 1 patient (3.9%) due to tachycardic atrial fibrillation. Patients on HVAD with a history of VAs (n = 13) had a significantly higher incidence of ICD interventions compared to patients with primary prophylactic indication for ICD (n = 13; 53.8% vs. 7.7%; P = 0.015). No disturbance of ICD function was seen after HVAD implantation.CONCLUSION: Combined ICD and HVAD therapy was safe and feasible, without electromagnetic interference between ICD and ventricular assist device. The incidence of ICD interventions was high in patients with a history of VAs, but low in patients with ICD implantation for primary prevention.

KW - Combined Modality Therapy/instrumentation

KW - Defibrillators, Implantable

KW - Equipment Design

KW - Equipment Failure Analysis

KW - Female

KW - Heart Failure/diagnosis

KW - Heart-Assist Devices

KW - Humans

KW - Male

KW - Middle Aged

KW - Treatment Outcome

U2 - 10.1111/jce.12455

DO - 10.1111/jce.12455

M3 - SCORING: Journal article

C2 - 24862733

VL - 25

SP - 1109

EP - 1114

JO - J CARDIOVASC ELECTR

JF - J CARDIOVASC ELECTR

SN - 1045-3873

IS - 10

ER -