Clinical and histological results of sensory recovery after radial foreann flap transfer
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Clinical and histological results of sensory recovery after radial foreann flap transfer. / Vesper, M; Heiland, M; Blake, F; Flinzberg, S; Schmelzle, R.
In: CLIN ORAL INVEST, Vol. 6, No. 2, 01.06.2002, p. 114-8.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
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TY - JOUR
T1 - Clinical and histological results of sensory recovery after radial foreann flap transfer
AU - Vesper, M
AU - Heiland, M
AU - Blake, F
AU - Flinzberg, S
AU - Schmelzle, R
PY - 2002/6/1
Y1 - 2002/6/1
N2 - The necessity of nerve anastomosis in an attempt to regain dermal sensitivity following pedicled or free-flap transfer has been the basis of many discussions. In our study, we investigated the degree of sensory recovery with emphasis on the different nerval qualities, on the radial forearm flap and correlated it to the histological and immunohistological findings. Nineteen patients with radial forearm free flap--five of whom underwent nerve anastomosis--were examined. The follow-up interval was 20.3 months (average) after surgical intervention. Histological examinations were performed on 13 of the 19 patients, in eight cases on one occasion and in five on more than one occasion. Seventeen patients experienced sensory recovery, whereby the degree and quality of dermal innervation varied. In comparison, the nerval reconstruction did not lead to any significant improvement. Based on our clinical results, we regard the nerve reconstruction during the radial forearm free flap transfer as unnecessary. To what extent this can be said for other flaps demands further investigation.
AB - The necessity of nerve anastomosis in an attempt to regain dermal sensitivity following pedicled or free-flap transfer has been the basis of many discussions. In our study, we investigated the degree of sensory recovery with emphasis on the different nerval qualities, on the radial forearm flap and correlated it to the histological and immunohistological findings. Nineteen patients with radial forearm free flap--five of whom underwent nerve anastomosis--were examined. The follow-up interval was 20.3 months (average) after surgical intervention. Histological examinations were performed on 13 of the 19 patients, in eight cases on one occasion and in five on more than one occasion. Seventeen patients experienced sensory recovery, whereby the degree and quality of dermal innervation varied. In comparison, the nerval reconstruction did not lead to any significant improvement. Based on our clinical results, we regard the nerve reconstruction during the radial forearm free flap transfer as unnecessary. To what extent this can be said for other flaps demands further investigation.
KW - Adolescent
KW - Adult
KW - Aged
KW - Alkaline Phosphatase
KW - Anastomosis, Surgical
KW - Biopsy
KW - Child
KW - Coloring Agents
KW - Female
KW - Fluorescent Antibody Technique, Indirect
KW - Follow-Up Studies
KW - Forearm
KW - Humans
KW - Male
KW - Middle Aged
KW - Neurofilament Proteins
KW - Radial Nerve
KW - Recovery of Function
KW - S100 Proteins
KW - Sensation
KW - Substance P
KW - Surgical Flaps
M3 - SCORING: Journal article
C2 - 12166711
VL - 6
SP - 114
EP - 118
JO - CLIN ORAL INVEST
JF - CLIN ORAL INVEST
SN - 1432-6981
IS - 2
ER -