Research ExplorerPublicationsClindamycin use in head and neck surgery elevates the rate o...

Clindamycin use in head and neck surgery elevates the rate of infections in tracheostomies

Standard

Clindamycin use in head and neck surgery elevates the rate of infections in tracheostomies. / Fiedler, Lukas; Herbst, Manuel; Hugo, Pereira.

In: EUR ARCH OTO-RHINO-L, Vol. 279, No. 7, 07.2022, p. 3581-3586.

Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

Harvard

Fiedler, L, Herbst, M & Hugo, P 2022, 'Clindamycin use in head and neck surgery elevates the rate of infections in tracheostomies', EUR ARCH OTO-RHINO-L, vol. 279, no. 7, pp. 3581-3586. https://doi.org/10.1007/s00405-022-07349-z

APA

Fiedler, L., Herbst, M., & Hugo, P. (2022). Clindamycin use in head and neck surgery elevates the rate of infections in tracheostomies. EUR ARCH OTO-RHINO-L, 279(7), 3581-3586. https://doi.org/10.1007/s00405-022-07349-z

Vancouver

Fiedler L, Herbst M, Hugo P. Clindamycin use in head and neck surgery elevates the rate of infections in tracheostomies. EUR ARCH OTO-RHINO-L. 2022 Jul;279(7):3581-3586. https://doi.org/10.1007/s00405-022-07349-z

Bibtex

@article{d6c965e471734487901ac1d3072ed2d5,
title = "Clindamycin use in head and neck surgery elevates the rate of infections in tracheostomies",
abstract = "BACKGROUND: Surgical site infection (SSI) in open surgical tracheostomy (ST) occurs in up to 33% of the cases. SSI can be reduced by a postoperative antibiotic prophylaxis (POAP). The effect of Clindamycin on SSIs in head and neck surgery (HNS) is discussed controversially in the literature.METHODS: An 8 year single-center retrospective comparative analysis of 441 STs (Visor-ST and Bjoerk-flap technique) performed within major HNS was evaluated due to the event of a SSI within 7 days and analyzed descriptively. Logistic regression model evaluated the impact of POAP with Clindamycin on SSIs.RESULTS: The use of Clindamycin showed twice the rate of ST-SSI as all patients that did not receive Clindamycin, treated with other perioperative antibiotics. (Fisher's p = 0.008) The logistic regression model could not prove a statistically significant impact. (OR = 2.91, p = 0.04).CONCLUSION: We recommend that Clindamycin should be reconsidered as a POAP regimen in ST. Further studies should evaluate alternatives for Penicillin-allergic patients.LEVEL OF EVIDENCE III: Comparative retrospective monocentric study.",
author = "Lukas Fiedler and Manuel Herbst and Pereira Hugo",
year = "2022",
month = jul,
doi = "10.1007/s00405-022-07349-z",
language = "English",
volume = "279",
pages = "3581--3586",
journal = "EUR ARCH OTO-RHINO-L",
issn = "0937-4477",
publisher = "Springer",
number = "7",

}

RIS

TY - JOUR

T1 - Clindamycin use in head and neck surgery elevates the rate of infections in tracheostomies

AU - Fiedler, Lukas

AU - Herbst, Manuel

AU - Hugo, Pereira

PY - 2022/7

Y1 - 2022/7

N2 - BACKGROUND: Surgical site infection (SSI) in open surgical tracheostomy (ST) occurs in up to 33% of the cases. SSI can be reduced by a postoperative antibiotic prophylaxis (POAP). The effect of Clindamycin on SSIs in head and neck surgery (HNS) is discussed controversially in the literature.METHODS: An 8 year single-center retrospective comparative analysis of 441 STs (Visor-ST and Bjoerk-flap technique) performed within major HNS was evaluated due to the event of a SSI within 7 days and analyzed descriptively. Logistic regression model evaluated the impact of POAP with Clindamycin on SSIs.RESULTS: The use of Clindamycin showed twice the rate of ST-SSI as all patients that did not receive Clindamycin, treated with other perioperative antibiotics. (Fisher's p = 0.008) The logistic regression model could not prove a statistically significant impact. (OR = 2.91, p = 0.04).CONCLUSION: We recommend that Clindamycin should be reconsidered as a POAP regimen in ST. Further studies should evaluate alternatives for Penicillin-allergic patients.LEVEL OF EVIDENCE III: Comparative retrospective monocentric study.

AB - BACKGROUND: Surgical site infection (SSI) in open surgical tracheostomy (ST) occurs in up to 33% of the cases. SSI can be reduced by a postoperative antibiotic prophylaxis (POAP). The effect of Clindamycin on SSIs in head and neck surgery (HNS) is discussed controversially in the literature.METHODS: An 8 year single-center retrospective comparative analysis of 441 STs (Visor-ST and Bjoerk-flap technique) performed within major HNS was evaluated due to the event of a SSI within 7 days and analyzed descriptively. Logistic regression model evaluated the impact of POAP with Clindamycin on SSIs.RESULTS: The use of Clindamycin showed twice the rate of ST-SSI as all patients that did not receive Clindamycin, treated with other perioperative antibiotics. (Fisher's p = 0.008) The logistic regression model could not prove a statistically significant impact. (OR = 2.91, p = 0.04).CONCLUSION: We recommend that Clindamycin should be reconsidered as a POAP regimen in ST. Further studies should evaluate alternatives for Penicillin-allergic patients.LEVEL OF EVIDENCE III: Comparative retrospective monocentric study.

U2 - 10.1007/s00405-022-07349-z

DO - 10.1007/s00405-022-07349-z

M3 - SCORING: Journal article

VL - 279

SP - 3581

EP - 3586

JO - EUR ARCH OTO-RHINO-L

JF - EUR ARCH OTO-RHINO-L

SN - 0937-4477

IS - 7

ER -