Citriperazines A-D produced by a marine algae-derived fungus Penicillium sp. KMM 4672

  • Anton Nikolaevich Yurchenko
  • Dmitry V Berdyshev
  • Olga F Smetanina
  • Elena V Ivanets
  • Olesya I Zhuravleva
  • Anton B Rasin
  • Yuliya V Khudyakova
  • Roman S Popov
  • Sergey A Dyshlovoy
  • Gunhild von Amsberg
  • Shamil Sh Afiyatullov

Related Research units

Abstract

Four new diketopiperazine alkaloids, citriperazines A-D were isolated from algae-derived Penicillium sp. KMM 4672. The structures of compounds 1-4 were determined using spectroscopic methods. The absolute configurations of compounds 1 and 4 were established by comparison of calculated and experimental ECD spectra. The cytotoxicity of compounds 1-4 against several human prostate cell lines was evaluated.

Bibliographical data

Original languageEnglish
ISSN1478-6419
DOIs
Publication statusPublished - 04.2020
PubMed 30663353