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Chronic feeding of carbonyl-iron and TMH-ferrocene in rats. Comparison of two iron-overload models with different iron absorption.

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Chronic feeding of carbonyl-iron and TMH-ferrocene in rats. Comparison of two iron-overload models with different iron absorption. / Nielsen, Peter; Heinelt, S; Düllmann, J.

In: COMP BIOCHEM PHYS C, Vol. 106, No. 2, 2, 1993, p. 429-436.

Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

Harvard

Nielsen, P, Heinelt, S & Düllmann, J 1993, 'Chronic feeding of carbonyl-iron and TMH-ferrocene in rats. Comparison of two iron-overload models with different iron absorption.', COMP BIOCHEM PHYS C, vol. 106, no. 2, 2, pp. 429-436. <http://www.ncbi.nlm.nih.gov/pubmed/7904915?dopt=Citation>

APA

Nielsen, P., Heinelt, S., & Düllmann, J. (1993). Chronic feeding of carbonyl-iron and TMH-ferrocene in rats. Comparison of two iron-overload models with different iron absorption. COMP BIOCHEM PHYS C, 106(2), 429-436. [2]. http://www.ncbi.nlm.nih.gov/pubmed/7904915?dopt=Citation

Vancouver

Nielsen P, Heinelt S, Düllmann J. Chronic feeding of carbonyl-iron and TMH-ferrocene in rats. Comparison of two iron-overload models with different iron absorption. COMP BIOCHEM PHYS C. 1993;106(2):429-436. 2.

Bibtex

@article{976c30a263824bf0966c386b0e8f58e6,
title = "Chronic feeding of carbonyl-iron and TMH-ferrocene in rats. Comparison of two iron-overload models with different iron absorption.",
abstract = "1. The use of carbonyl-iron and (3,5,5-trimethylhexanoyl)-ferrocene (TMH-ferrocene) as a dietary iron-overload model was studied in rats using 59Fe-labelled compounds. 2. The intestinal absorption of carbonyl-iron but not from the TMH-ferrocene-iron was dependent upon the dosage and downregulated in iron-loaded rats. 3. In both models, and similar to hereditary haemochromatosis in humans, the storage of excess iron in the liver started in hepatocytes, whereas the range of iron-loading was strikingly different. 4. Because of the fast and progressive iron-loading, the TMH-ferrocene-model is the most encouraging animal model for experimental haemochromatosis.",
author = "Peter Nielsen and S Heinelt and J D{\"u}llmann",
year = "1993",
language = "Deutsch",
volume = "106",
pages = "429--436",
journal = "COMP BIOCHEM PHYS C",
issn = "1532-0456",
publisher = "Elsevier Inc.",
number = "2",

}

RIS

TY - JOUR

T1 - Chronic feeding of carbonyl-iron and TMH-ferrocene in rats. Comparison of two iron-overload models with different iron absorption.

AU - Nielsen, Peter

AU - Heinelt, S

AU - Düllmann, J

PY - 1993

Y1 - 1993

N2 - 1. The use of carbonyl-iron and (3,5,5-trimethylhexanoyl)-ferrocene (TMH-ferrocene) as a dietary iron-overload model was studied in rats using 59Fe-labelled compounds. 2. The intestinal absorption of carbonyl-iron but not from the TMH-ferrocene-iron was dependent upon the dosage and downregulated in iron-loaded rats. 3. In both models, and similar to hereditary haemochromatosis in humans, the storage of excess iron in the liver started in hepatocytes, whereas the range of iron-loading was strikingly different. 4. Because of the fast and progressive iron-loading, the TMH-ferrocene-model is the most encouraging animal model for experimental haemochromatosis.

AB - 1. The use of carbonyl-iron and (3,5,5-trimethylhexanoyl)-ferrocene (TMH-ferrocene) as a dietary iron-overload model was studied in rats using 59Fe-labelled compounds. 2. The intestinal absorption of carbonyl-iron but not from the TMH-ferrocene-iron was dependent upon the dosage and downregulated in iron-loaded rats. 3. In both models, and similar to hereditary haemochromatosis in humans, the storage of excess iron in the liver started in hepatocytes, whereas the range of iron-loading was strikingly different. 4. Because of the fast and progressive iron-loading, the TMH-ferrocene-model is the most encouraging animal model for experimental haemochromatosis.

M3 - SCORING: Zeitschriftenaufsatz

VL - 106

SP - 429

EP - 436

JO - COMP BIOCHEM PHYS C

JF - COMP BIOCHEM PHYS C

SN - 1532-0456

IS - 2

M1 - 2

ER -