Chromosomal rearrangements in PLAG1 of myoepithelial salivary gland tumours.
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Chromosomal rearrangements in PLAG1 of myoepithelial salivary gland tumours. / Friedrich, Reinhard; Dilcher, Julia; Jaehne, Michael; Löning, Thomas.
In: ANTICANCER RES, Vol. 32, No. 5, 5, 2012, p. 1977-1981.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
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TY - JOUR
T1 - Chromosomal rearrangements in PLAG1 of myoepithelial salivary gland tumours.
AU - Friedrich, Reinhard
AU - Dilcher, Julia
AU - Jaehne, Michael
AU - Löning, Thomas
PY - 2012
Y1 - 2012
N2 - PLAG1 mutations are related to the development of pleomorphic adenomas. A specific aspect of PA is the histological diversity of this entity, containing cells with mesenchymal, epithelial and myoepithelial differentiation. Evidence for myoepithelial cells in PA raises the question whether the very rare entity of pure myoepithelial salivary gland tumours shows chromosomal translocations and rearrangements and whether activation of PLAG1 can be detected.
AB - PLAG1 mutations are related to the development of pleomorphic adenomas. A specific aspect of PA is the histological diversity of this entity, containing cells with mesenchymal, epithelial and myoepithelial differentiation. Evidence for myoepithelial cells in PA raises the question whether the very rare entity of pure myoepithelial salivary gland tumours shows chromosomal translocations and rearrangements and whether activation of PLAG1 can be detected.
KW - Adult
KW - Humans
KW - Male
KW - Aged
KW - Female
KW - Middle Aged
KW - Adolescent
KW - In Situ Hybridization, Fluorescence
KW - Chromosomes, Human, Pair 8
KW - DNA-Binding Proteins/genetics
KW - Translocation, Genetic
KW - Salivary Gland Neoplasms/genetics
KW - Myoepithelioma/genetics
KW - Adult
KW - Humans
KW - Male
KW - Aged
KW - Female
KW - Middle Aged
KW - Adolescent
KW - In Situ Hybridization, Fluorescence
KW - Chromosomes, Human, Pair 8
KW - DNA-Binding Proteins/genetics
KW - Translocation, Genetic
KW - Salivary Gland Neoplasms/genetics
KW - Myoepithelioma/genetics
M3 - SCORING: Journal article
VL - 32
SP - 1977
EP - 1981
JO - ANTICANCER RES
JF - ANTICANCER RES
SN - 0250-7005
IS - 5
M1 - 5
ER -