Cholangiocellular carcinoma--the role of caudate lobe resection and mesohepatectomy

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Cholangiocellular carcinoma--the role of caudate lobe resection and mesohepatectomy. / Malago, Massimo; Frilling, Andrea; Li, Jun; Lang, Hauke; Broelsch, Christoph E.

In: HPB, Vol. 10, No. 3, 2008, p. 179-82.

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@article{9bc0cf117b9a4948aee6582d6b919c0d,
title = "Cholangiocellular carcinoma--the role of caudate lobe resection and mesohepatectomy",
abstract = "BACKGROUND: The surgical treatment of perihilar cholangiocellular carcinoma (CCC) is challenging due to the adjacency of the tumor to the hilar vessels, major hepatic veins, bile ducts, and the inferior vena cava. Additionally, the tumour frequently infiltrates the parenchyma of the caudate lobe or/and invades its bile ducts.CONSENSUS STATEMENTS: Negative margin caudate hepatectomy is rarely feasible. Isolated partial or complete caudate lobe resection is an oncologically inadequate procedure. Extended hepatectomies in combination with caudate lobectomy can provide prolonged survival, even in patients with advanced CCC. Mesohepatectomy is an oncologically adequate procedure for selected patients with CCC and compromised liver function. The procedure is technically demanding; however, it lowers the risk of postoperative liver failure.",
keywords = "Journal Article",
author = "Massimo Malago and Andrea Frilling and Jun Li and Hauke Lang and Broelsch, {Christoph E}",
year = "2008",
doi = "10.1080/13651820801992500",
language = "English",
volume = "10",
pages = "179--82",
journal = "HPB",
issn = "1365-182X",
publisher = "John Wiley and Sons Inc.",
number = "3",

}

RIS

TY - JOUR

T1 - Cholangiocellular carcinoma--the role of caudate lobe resection and mesohepatectomy

AU - Malago, Massimo

AU - Frilling, Andrea

AU - Li, Jun

AU - Lang, Hauke

AU - Broelsch, Christoph E

PY - 2008

Y1 - 2008

N2 - BACKGROUND: The surgical treatment of perihilar cholangiocellular carcinoma (CCC) is challenging due to the adjacency of the tumor to the hilar vessels, major hepatic veins, bile ducts, and the inferior vena cava. Additionally, the tumour frequently infiltrates the parenchyma of the caudate lobe or/and invades its bile ducts.CONSENSUS STATEMENTS: Negative margin caudate hepatectomy is rarely feasible. Isolated partial or complete caudate lobe resection is an oncologically inadequate procedure. Extended hepatectomies in combination with caudate lobectomy can provide prolonged survival, even in patients with advanced CCC. Mesohepatectomy is an oncologically adequate procedure for selected patients with CCC and compromised liver function. The procedure is technically demanding; however, it lowers the risk of postoperative liver failure.

AB - BACKGROUND: The surgical treatment of perihilar cholangiocellular carcinoma (CCC) is challenging due to the adjacency of the tumor to the hilar vessels, major hepatic veins, bile ducts, and the inferior vena cava. Additionally, the tumour frequently infiltrates the parenchyma of the caudate lobe or/and invades its bile ducts.CONSENSUS STATEMENTS: Negative margin caudate hepatectomy is rarely feasible. Isolated partial or complete caudate lobe resection is an oncologically inadequate procedure. Extended hepatectomies in combination with caudate lobectomy can provide prolonged survival, even in patients with advanced CCC. Mesohepatectomy is an oncologically adequate procedure for selected patients with CCC and compromised liver function. The procedure is technically demanding; however, it lowers the risk of postoperative liver failure.

KW - Journal Article

U2 - 10.1080/13651820801992500

DO - 10.1080/13651820801992500

M3 - SCORING: Journal article

C2 - 18773050

VL - 10

SP - 179

EP - 182

JO - HPB

JF - HPB

SN - 1365-182X

IS - 3

ER -