Childhood Trauma and Somatic and Mental Illness in Adulthood
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Childhood Trauma and Somatic and Mental Illness in Adulthood. / Klinger-König, Johanna; Erhardt, Angelika; Streit, Fabian; Völker, Maja P; Schulze, Matthias B; Keil, Thomas; Fricke, Julia; Castell, Stefanie; Klett-Tammen, Carolina J; Pischon, Tobias; Karch, André; Teismann, Henning; Michels, Karin B; Greiser, K Halina; Becher, Heiko; Karrasch, Stefan; Ahrens, Wolfgang; Meinke-Franze, Claudia; Schipf, Sabine; Mikolajczyk, Rafael; Führer, Amand; Brandes, Berit; Schmidt, Börge; Emmel, Carina; Leitzmann, Michael; Konzok, Julian; Peters, Anette; Obi, Nadia; Brenner, Hermann; Holleczek, Bernd; Moreno Velásquez, Ilais; Deckert, Jürgen; Baune, Bernhard T; Rietschel, Marcella; Berger, Klaus; Grabe, Hans J.
In: DTSCH ARZTEBL INT, Vol. 121, No. 1, 12.01.2024, p. 1-8.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
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TY - JOUR
T1 - Childhood Trauma and Somatic and Mental Illness in Adulthood
AU - Klinger-König, Johanna
AU - Erhardt, Angelika
AU - Streit, Fabian
AU - Völker, Maja P
AU - Schulze, Matthias B
AU - Keil, Thomas
AU - Fricke, Julia
AU - Castell, Stefanie
AU - Klett-Tammen, Carolina J
AU - Pischon, Tobias
AU - Karch, André
AU - Teismann, Henning
AU - Michels, Karin B
AU - Greiser, K Halina
AU - Becher, Heiko
AU - Karrasch, Stefan
AU - Ahrens, Wolfgang
AU - Meinke-Franze, Claudia
AU - Schipf, Sabine
AU - Mikolajczyk, Rafael
AU - Führer, Amand
AU - Brandes, Berit
AU - Schmidt, Börge
AU - Emmel, Carina
AU - Leitzmann, Michael
AU - Konzok, Julian
AU - Peters, Anette
AU - Obi, Nadia
AU - Brenner, Hermann
AU - Holleczek, Bernd
AU - Moreno Velásquez, Ilais
AU - Deckert, Jürgen
AU - Baune, Bernhard T
AU - Rietschel, Marcella
AU - Berger, Klaus
AU - Grabe, Hans J
PY - 2024/1/12
Y1 - 2024/1/12
N2 - BACKGROUND: Childhood trauma is associated with somatic and mental illness in adulthood. The strength of the association varies as a function of age, sex, and type of trauma. Pertinent studies to date have mainly focused on individual diseases. In this study, we investigate the association between childhood trauma and a multiplicity of somatic and mental illnesses in adulthood.METHODS: Data from 156 807 NAKO Health Study participants were analyzed by means of logistic regressions, with adjustment for age, sex, years of education, and study site. The Childhood Trauma Screener differentiated between no/minor (n = 115 891) and moderate/severe childhood trauma (n = 40 916). The outcome variables were medical diagnoses of five somatic and two mental health conditions as stated in the clinical history.RESULTS: Persons with childhood trauma were more likely to bear a diagnosis of all of the studied conditions: cancer (odds ratio [OR] = 1.10; 95% confidence interval: [1.05; 1.15]), myocardial infarction (OR = 1.13 [1.03; 1.24]), diabetes (OR = 1.16, [1.10; 1.23]), stroke (OR = 1.35 [1.23; 1.48]), chronic obstructive pulmonary disease (OR = 1.45 [1.38; 1.52]), depression (OR = 2.36 [2.29; 2.43]), and anxiety disorders (OR = 2.08 [2.00; 2.17]). All of these associations were stronger in younger persons, regardless of the nature of childhood trauma. Differences between the sexes were observed only for some of these associations.CONCLUSION: Childhood trauma was associated with a higher probability of developing mental as well as somatic illness in adulthood. As childhood trauma is an element of individual history that the victim has little to no control over, and because the illnesses that can arise in adulthood in association with it are a heavy burden on the affected persons and on society, there is a need for research on these associations and for the development of preventive measures.
AB - BACKGROUND: Childhood trauma is associated with somatic and mental illness in adulthood. The strength of the association varies as a function of age, sex, and type of trauma. Pertinent studies to date have mainly focused on individual diseases. In this study, we investigate the association between childhood trauma and a multiplicity of somatic and mental illnesses in adulthood.METHODS: Data from 156 807 NAKO Health Study participants were analyzed by means of logistic regressions, with adjustment for age, sex, years of education, and study site. The Childhood Trauma Screener differentiated between no/minor (n = 115 891) and moderate/severe childhood trauma (n = 40 916). The outcome variables were medical diagnoses of five somatic and two mental health conditions as stated in the clinical history.RESULTS: Persons with childhood trauma were more likely to bear a diagnosis of all of the studied conditions: cancer (odds ratio [OR] = 1.10; 95% confidence interval: [1.05; 1.15]), myocardial infarction (OR = 1.13 [1.03; 1.24]), diabetes (OR = 1.16, [1.10; 1.23]), stroke (OR = 1.35 [1.23; 1.48]), chronic obstructive pulmonary disease (OR = 1.45 [1.38; 1.52]), depression (OR = 2.36 [2.29; 2.43]), and anxiety disorders (OR = 2.08 [2.00; 2.17]). All of these associations were stronger in younger persons, regardless of the nature of childhood trauma. Differences between the sexes were observed only for some of these associations.CONCLUSION: Childhood trauma was associated with a higher probability of developing mental as well as somatic illness in adulthood. As childhood trauma is an element of individual history that the victim has little to no control over, and because the illnesses that can arise in adulthood in association with it are a heavy burden on the affected persons and on society, there is a need for research on these associations and for the development of preventive measures.
KW - Humans
KW - Adverse Childhood Experiences
KW - Mental Disorders/epidemiology
KW - Anxiety Disorders
KW - Diabetes Mellitus
U2 - 10.3238/arztebl.m2023.0225
DO - 10.3238/arztebl.m2023.0225
M3 - SCORING: Journal article
C2 - 37876295
VL - 121
SP - 1
EP - 8
JO - DTSCH ARZTEBL INT
JF - DTSCH ARZTEBL INT
SN - 1866-0452
IS - 1
ER -
