Chemotherapie von Keimzelltumoren

TY - JOUR

T1 - Chemotherapie von Keimzelltumoren

AU - Beyer, J

AU - Bokemeyer, C

PY - 2004/12

Y1 - 2004/12

N2 - Chemotherapy for germ cell cancer is usually indicated in patients who present with metastatic disease, suffer relapses, or progress after their initial treatment. Rarely is chemotherapy needed in the palliative treatment of refractory patients. However, more recently chemotherapy has been demonstrated to benefit also patients with early stages of seminoma as well as nonseminoma. Therefore, the most recent European consensus guidelines on treatment and diagnosis of germ cell cancer list chemotherapy as an alternative treatment option in the early tumor stages I and II. The application of chemotherapy represents a challenge for both patients and the treating physician who must be experienced with a broad array of chemotherapy regimens and competent in their application. Particularly the treatment of patients with advanced tumor stages requires good clinical skills on the part of the treating oncologist. If excessive toxicity is to be avoided and a curative treatment option maintained, overtreatment as well as undertreatment are notorious pitfalls.

AB - Chemotherapy for germ cell cancer is usually indicated in patients who present with metastatic disease, suffer relapses, or progress after their initial treatment. Rarely is chemotherapy needed in the palliative treatment of refractory patients. However, more recently chemotherapy has been demonstrated to benefit also patients with early stages of seminoma as well as nonseminoma. Therefore, the most recent European consensus guidelines on treatment and diagnosis of germ cell cancer list chemotherapy as an alternative treatment option in the early tumor stages I and II. The application of chemotherapy represents a challenge for both patients and the treating physician who must be experienced with a broad array of chemotherapy regimens and competent in their application. Particularly the treatment of patients with advanced tumor stages requires good clinical skills on the part of the treating oncologist. If excessive toxicity is to be avoided and a curative treatment option maintained, overtreatment as well as undertreatment are notorious pitfalls.

KW - Antineoplastic Agents

KW - Chemotherapy, Adjuvant

KW - Drug Therapy

KW - Europe

KW - Humans

KW - Male

KW - Neoplasms, Germ Cell and Embryonal

KW - Palliative Care

KW - Physician's Practice Patterns

KW - Practice Guidelines as Topic

KW - Risk Assessment

KW - Risk Factors

KW - Testicular Neoplasms

KW - Treatment Outcome

U2 - 10.1007/s00120-004-0704-5

DO - 10.1007/s00120-004-0704-5

M3 - SCORING: Zeitschriftenaufsatz

C2 - 15592707

VL - 43

SP - 1507

EP - 1513

JO - UROLOGE

JF - UROLOGE

SN - 0340-2592

IS - 12

ER -