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Challenges in the interdisciplinary treatment of leakages after left-sided colorectal surgery: endoscopic negative pressure therapy, open-pore film drainage therapy and beyond

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Challenges in the interdisciplinary treatment of leakages after left-sided colorectal surgery: endoscopic negative pressure therapy, open-pore film drainage therapy and beyond. / Scognamiglio, Pasquale; Seeger, Anja; Reeh, Matthias; Melling, Nathaniel; Karstens, Karl F; Rösch, Thomas; Izbicki, Jakob R; Kantowski, Marcus; Tachezy, Michael.

In: INT J COLORECTAL DIS, Vol. 38, No. 1, 19.05.2023, p. 138.

Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

Harvard

Scognamiglio, P, Seeger, A, Reeh, M, Melling, N, Karstens, KF, Rösch, T, Izbicki, JR, Kantowski, M & Tachezy, M 2023, 'Challenges in the interdisciplinary treatment of leakages after left-sided colorectal surgery: endoscopic negative pressure therapy, open-pore film drainage therapy and beyond', INT J COLORECTAL DIS, vol. 38, no. 1, pp. 138. https://doi.org/10.1007/s00384-023-04418-5

APA

Scognamiglio, P., Seeger, A., Reeh, M., Melling, N., Karstens, K. F., Rösch, T., Izbicki, J. R., Kantowski, M., & Tachezy, M. (2023). Challenges in the interdisciplinary treatment of leakages after left-sided colorectal surgery: endoscopic negative pressure therapy, open-pore film drainage therapy and beyond. INT J COLORECTAL DIS, 38(1), 138. https://doi.org/10.1007/s00384-023-04418-5

Vancouver

Scognamiglio P, Seeger A, Reeh M, Melling N, Karstens KF, Rösch T et al. Challenges in the interdisciplinary treatment of leakages after left-sided colorectal surgery: endoscopic negative pressure therapy, open-pore film drainage therapy and beyond. INT J COLORECTAL DIS. 2023 May 19;38(1):138. https://doi.org/10.1007/s00384-023-04418-5

Bibtex

@article{7302196b4dfd4f2698b4fc2e38d538c1,
title = "Challenges in the interdisciplinary treatment of leakages after left-sided colorectal surgery: endoscopic negative pressure therapy, open-pore film drainage therapy and beyond",
abstract = "PURPOSE: The treatment of anastomotic leakage after left colorectal surgery remains challenging. Since its introduction, endoscopic negative pressure therapy (ENPT) has proven to be advantageous, reducing the necessity of surgical revision. The aim of our study is to present our experience with endoscopic treatment of colorectal leakages and to identify potential factors influencing treatment outcome.METHODS: Patients who underwent endoscopic treatment of colorectal leakage were retrospectively analyzed. Primary endpoint was the healing rate and success of endoscopic therapy.RESULTS: We identified 59 patients treated with ENPT between January 2009 and December 2019. The overall closure rate was 83%, whereas only 60% of the patients were successfully treated with ENPT and 23% needed further surgery. The time between diagnosis of leakage and uptake of endoscopic treatment did not influence the closure rate, but patients with chronic fistula (> 4 weeks) showed a significantly higher reoperation rate than those with an acute fistula (94% vs 6%, p = 0.01).CONCLUSION: ENPT is a successful treatment option for colorectal leakages, which appears to be more favorable when started early. Further studies are still needed to better describe its healing potential, but it deserves an integral role in the interdisciplinary treatment of anastomotic leakages.",
keywords = "Humans, Retrospective Studies, Colorectal Surgery, Anastomotic Leak/etiology, Drainage, Anastomosis, Surgical/adverse effects, Fistula/etiology, Colorectal Neoplasms/surgery, Negative-Pressure Wound Therapy",
author = "Pasquale Scognamiglio and Anja Seeger and Matthias Reeh and Nathaniel Melling and Karstens, {Karl F} and Thomas R{\"o}sch and Izbicki, {Jakob R} and Marcus Kantowski and Michael Tachezy",
note = "{\textcopyright} 2023. The Author(s).",
year = "2023",
month = may,
day = "19",
doi = "10.1007/s00384-023-04418-5",
language = "English",
volume = "38",
pages = "138",
journal = "INT J COLORECTAL DIS",
issn = "0179-1958",
publisher = "Springer",
number = "1",

}

RIS

TY - JOUR

T1 - Challenges in the interdisciplinary treatment of leakages after left-sided colorectal surgery: endoscopic negative pressure therapy, open-pore film drainage therapy and beyond

AU - Scognamiglio, Pasquale

AU - Seeger, Anja

AU - Reeh, Matthias

AU - Melling, Nathaniel

AU - Karstens, Karl F

AU - Rösch, Thomas

AU - Izbicki, Jakob R

AU - Kantowski, Marcus

AU - Tachezy, Michael

N1 - © 2023. The Author(s).

PY - 2023/5/19

Y1 - 2023/5/19

N2 - PURPOSE: The treatment of anastomotic leakage after left colorectal surgery remains challenging. Since its introduction, endoscopic negative pressure therapy (ENPT) has proven to be advantageous, reducing the necessity of surgical revision. The aim of our study is to present our experience with endoscopic treatment of colorectal leakages and to identify potential factors influencing treatment outcome.METHODS: Patients who underwent endoscopic treatment of colorectal leakage were retrospectively analyzed. Primary endpoint was the healing rate and success of endoscopic therapy.RESULTS: We identified 59 patients treated with ENPT between January 2009 and December 2019. The overall closure rate was 83%, whereas only 60% of the patients were successfully treated with ENPT and 23% needed further surgery. The time between diagnosis of leakage and uptake of endoscopic treatment did not influence the closure rate, but patients with chronic fistula (> 4 weeks) showed a significantly higher reoperation rate than those with an acute fistula (94% vs 6%, p = 0.01).CONCLUSION: ENPT is a successful treatment option for colorectal leakages, which appears to be more favorable when started early. Further studies are still needed to better describe its healing potential, but it deserves an integral role in the interdisciplinary treatment of anastomotic leakages.

AB - PURPOSE: The treatment of anastomotic leakage after left colorectal surgery remains challenging. Since its introduction, endoscopic negative pressure therapy (ENPT) has proven to be advantageous, reducing the necessity of surgical revision. The aim of our study is to present our experience with endoscopic treatment of colorectal leakages and to identify potential factors influencing treatment outcome.METHODS: Patients who underwent endoscopic treatment of colorectal leakage were retrospectively analyzed. Primary endpoint was the healing rate and success of endoscopic therapy.RESULTS: We identified 59 patients treated with ENPT between January 2009 and December 2019. The overall closure rate was 83%, whereas only 60% of the patients were successfully treated with ENPT and 23% needed further surgery. The time between diagnosis of leakage and uptake of endoscopic treatment did not influence the closure rate, but patients with chronic fistula (> 4 weeks) showed a significantly higher reoperation rate than those with an acute fistula (94% vs 6%, p = 0.01).CONCLUSION: ENPT is a successful treatment option for colorectal leakages, which appears to be more favorable when started early. Further studies are still needed to better describe its healing potential, but it deserves an integral role in the interdisciplinary treatment of anastomotic leakages.

KW - Humans

KW - Retrospective Studies

KW - Colorectal Surgery

KW - Anastomotic Leak/etiology

KW - Drainage

KW - Anastomosis, Surgical/adverse effects

KW - Fistula/etiology

KW - Colorectal Neoplasms/surgery

KW - Negative-Pressure Wound Therapy

U2 - 10.1007/s00384-023-04418-5

DO - 10.1007/s00384-023-04418-5

M3 - SCORING: Journal article

C2 - 37204614

VL - 38

SP - 138

JO - INT J COLORECTAL DIS

JF - INT J COLORECTAL DIS

SN - 0179-1958

IS - 1

ER -