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Central venous pressure at emergency room presentation predicts cardiac rehospitalization in patients with decompensated heart failure

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Central venous pressure at emergency room presentation predicts cardiac rehospitalization in patients with decompensated heart failure. / Uthoff, Heiko; Thalhammer, Christoph; Potocki, Mihael; Reichlin, Tobias; Noveanu, Markus; Aschwanden, Markus; Staub, Daniel; Arenja, Nisha; Socrates, Thenral; Twerenbold, Raphael; Mutschmann-Sanchez, Sarah; Heinisch, Corinna; Jaeger, Kurt A; Mebazaa, Alexandre; Mueller, Christian.

In: EUR J HEART FAIL, Vol. 12, No. 5, 05.2010, p. 469-76.

Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

Harvard

Uthoff, H, Thalhammer, C, Potocki, M, Reichlin, T, Noveanu, M, Aschwanden, M, Staub, D, Arenja, N, Socrates, T, Twerenbold, R, Mutschmann-Sanchez, S, Heinisch, C, Jaeger, KA, Mebazaa, A & Mueller, C 2010, 'Central venous pressure at emergency room presentation predicts cardiac rehospitalization in patients with decompensated heart failure', EUR J HEART FAIL, vol. 12, no. 5, pp. 469-76. https://doi.org/10.1093/eurjhf/hfq024

APA

Uthoff, H., Thalhammer, C., Potocki, M., Reichlin, T., Noveanu, M., Aschwanden, M., Staub, D., Arenja, N., Socrates, T., Twerenbold, R., Mutschmann-Sanchez, S., Heinisch, C., Jaeger, K. A., Mebazaa, A., & Mueller, C. (2010). Central venous pressure at emergency room presentation predicts cardiac rehospitalization in patients with decompensated heart failure. EUR J HEART FAIL, 12(5), 469-76. https://doi.org/10.1093/eurjhf/hfq024

Vancouver

Uthoff H, Thalhammer C, Potocki M, Reichlin T, Noveanu M, Aschwanden M et al. Central venous pressure at emergency room presentation predicts cardiac rehospitalization in patients with decompensated heart failure. EUR J HEART FAIL. 2010 May;12(5):469-76. https://doi.org/10.1093/eurjhf/hfq024

Bibtex

@article{20a37f08811a4516b97d12ba98848a8b,
title = "Central venous pressure at emergency room presentation predicts cardiac rehospitalization in patients with decompensated heart failure",
abstract = "AIMS: To investigate the relationship between central venous pressure (CVP) at presentation to the emergency room (ER) and the risk of cardiac rehospitalization and mortality in patients with decompensated heart failure (DHF).METHODS AND RESULTS: Central venous pressure was determined non-invasively using high-resolution compression sonography at presentation in 100 patients with DHF. Cardiac hospitalizations and cardiac and all-cause mortality were assessed as a function of continuous CVP levels and predefined CVP categories (low <6 cm H(2)O, intermediate 6-23 cm H(2)O, and high >23 cm H(2)O). Endpoints were adjudicated blinded to CVP. At presentation, mean age was 78 +/- 11 years, 60% of patients were male, mean B-type natriuretic peptide level was 1904 +/- 1592 pg/mL, and mean CVP was 13.7 +/- 7.0 cm H(2)O (range 0-33). During follow-up (median 12 months), 25 cardiac rehospitalizations, 26 cardiac deaths, and 7 non-cardiac deaths occurred. Univariate and stepwise multivariate Cox regression analysis revealed an independent relationship between CVP and cardiac rehospitalization (HR 1.09, 95% CI 1.01-1.18, P = 0.034). Kaplan-Meier analyses confirmed a stepwise increase in cardiac rehospitalization for low-to-high CVP (log-rank test P = 0.015). No association between CVP and (cardiac) mortality was detectable.CONCLUSION: Central venous pressure at ER presentation in patients with DHF is an independent predictor of cardiac rehospitalization but not of cardiac and all-cause mortality.",
keywords = "Aged, Aged, 80 and over, Central Venous Pressure, Confidence Intervals, Dyspnea, Emergency Service, Hospital/statistics & numerical data, Europe, Female, Health Status Indicators, Heart Failure/diagnosis, Hospitalization/statistics & numerical data, Humans, Kaplan-Meier Estimate, Length of Stay, Male, Multivariate Analysis, Natriuretic Peptide, Brain/blood, Peptide Fragments/blood, Prognosis, Proportional Hazards Models, Risk Assessment",
author = "Heiko Uthoff and Christoph Thalhammer and Mihael Potocki and Tobias Reichlin and Markus Noveanu and Markus Aschwanden and Daniel Staub and Nisha Arenja and Thenral Socrates and Raphael Twerenbold and Sarah Mutschmann-Sanchez and Corinna Heinisch and Jaeger, {Kurt A} and Alexandre Mebazaa and Christian Mueller",
year = "2010",
month = may,
doi = "10.1093/eurjhf/hfq024",
language = "English",
volume = "12",
pages = "469--76",
journal = "EUR J HEART FAIL",
issn = "1388-9842",
publisher = "Oxford University Press",
number = "5",

}

RIS

TY - JOUR

T1 - Central venous pressure at emergency room presentation predicts cardiac rehospitalization in patients with decompensated heart failure

AU - Uthoff, Heiko

AU - Thalhammer, Christoph

AU - Potocki, Mihael

AU - Reichlin, Tobias

AU - Noveanu, Markus

AU - Aschwanden, Markus

AU - Staub, Daniel

AU - Arenja, Nisha

AU - Socrates, Thenral

AU - Twerenbold, Raphael

AU - Mutschmann-Sanchez, Sarah

AU - Heinisch, Corinna

AU - Jaeger, Kurt A

AU - Mebazaa, Alexandre

AU - Mueller, Christian

PY - 2010/5

Y1 - 2010/5

N2 - AIMS: To investigate the relationship between central venous pressure (CVP) at presentation to the emergency room (ER) and the risk of cardiac rehospitalization and mortality in patients with decompensated heart failure (DHF).METHODS AND RESULTS: Central venous pressure was determined non-invasively using high-resolution compression sonography at presentation in 100 patients with DHF. Cardiac hospitalizations and cardiac and all-cause mortality were assessed as a function of continuous CVP levels and predefined CVP categories (low <6 cm H(2)O, intermediate 6-23 cm H(2)O, and high >23 cm H(2)O). Endpoints were adjudicated blinded to CVP. At presentation, mean age was 78 +/- 11 years, 60% of patients were male, mean B-type natriuretic peptide level was 1904 +/- 1592 pg/mL, and mean CVP was 13.7 +/- 7.0 cm H(2)O (range 0-33). During follow-up (median 12 months), 25 cardiac rehospitalizations, 26 cardiac deaths, and 7 non-cardiac deaths occurred. Univariate and stepwise multivariate Cox regression analysis revealed an independent relationship between CVP and cardiac rehospitalization (HR 1.09, 95% CI 1.01-1.18, P = 0.034). Kaplan-Meier analyses confirmed a stepwise increase in cardiac rehospitalization for low-to-high CVP (log-rank test P = 0.015). No association between CVP and (cardiac) mortality was detectable.CONCLUSION: Central venous pressure at ER presentation in patients with DHF is an independent predictor of cardiac rehospitalization but not of cardiac and all-cause mortality.

AB - AIMS: To investigate the relationship between central venous pressure (CVP) at presentation to the emergency room (ER) and the risk of cardiac rehospitalization and mortality in patients with decompensated heart failure (DHF).METHODS AND RESULTS: Central venous pressure was determined non-invasively using high-resolution compression sonography at presentation in 100 patients with DHF. Cardiac hospitalizations and cardiac and all-cause mortality were assessed as a function of continuous CVP levels and predefined CVP categories (low <6 cm H(2)O, intermediate 6-23 cm H(2)O, and high >23 cm H(2)O). Endpoints were adjudicated blinded to CVP. At presentation, mean age was 78 +/- 11 years, 60% of patients were male, mean B-type natriuretic peptide level was 1904 +/- 1592 pg/mL, and mean CVP was 13.7 +/- 7.0 cm H(2)O (range 0-33). During follow-up (median 12 months), 25 cardiac rehospitalizations, 26 cardiac deaths, and 7 non-cardiac deaths occurred. Univariate and stepwise multivariate Cox regression analysis revealed an independent relationship between CVP and cardiac rehospitalization (HR 1.09, 95% CI 1.01-1.18, P = 0.034). Kaplan-Meier analyses confirmed a stepwise increase in cardiac rehospitalization for low-to-high CVP (log-rank test P = 0.015). No association between CVP and (cardiac) mortality was detectable.CONCLUSION: Central venous pressure at ER presentation in patients with DHF is an independent predictor of cardiac rehospitalization but not of cardiac and all-cause mortality.

KW - Aged

KW - Aged, 80 and over

KW - Central Venous Pressure

KW - Confidence Intervals

KW - Dyspnea

KW - Emergency Service, Hospital/statistics & numerical data

KW - Europe

KW - Female

KW - Health Status Indicators

KW - Heart Failure/diagnosis

KW - Hospitalization/statistics & numerical data

KW - Humans

KW - Kaplan-Meier Estimate

KW - Length of Stay

KW - Male

KW - Multivariate Analysis

KW - Natriuretic Peptide, Brain/blood

KW - Peptide Fragments/blood

KW - Prognosis

KW - Proportional Hazards Models

KW - Risk Assessment

U2 - 10.1093/eurjhf/hfq024

DO - 10.1093/eurjhf/hfq024

M3 - SCORING: Journal article

C2 - 20223880

VL - 12

SP - 469

EP - 476

JO - EUR J HEART FAIL

JF - EUR J HEART FAIL

SN - 1388-9842

IS - 5

ER -