Cellular and tumor radiosensitivity is correlated to epidermal growth factor receptor protein expression level in tumors without EGFR amplification.

  • Ulla Kasten-Pisula
  • Jarob Saker
  • Wolfgang Eicheler
  • Mechthild Krause
  • Ala Yaromina
  • Sönke Meyer-Staeckling
  • Benjamin Scherkl
  • Malte Kriegs
  • Burkhard Brandt
  • Reidar Grénman
  • Cordula Petersen
  • Michael Baumann
  • Ekkehard Dikomey

Abstract

There is conflicting evidence for whether the expression of epidermal growth factor receptor in human tumors can be used as a marker of radioresponse. Therefore, this association was studied in a systematic manner using squamous cell carcinoma (SCC) cell lines grown as cell cultures and xenografts.

Bibliographical data

Original languageEnglish
Article number4
ISSN0360-3016
Publication statusPublished - 2011
pubmed 21514063