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Cell type-specific gating of perisomatic inhibition by cholecystokinin

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Cell type-specific gating of perisomatic inhibition by cholecystokinin. / Földy, Csaba; Lee, Soo Yeun; Szabadics, János; Neu, Axel; Soltesz, Ivan.

In: NAT NEUROSCI, Vol. 10, No. 9, 01.09.2007, p. 1128-30.

Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

Harvard

Földy, C, Lee, SY, Szabadics, J, Neu, A & Soltesz, I 2007, 'Cell type-specific gating of perisomatic inhibition by cholecystokinin', NAT NEUROSCI, vol. 10, no. 9, pp. 1128-30. https://doi.org/10.1038/nn1952

APA

Földy, C., Lee, S. Y., Szabadics, J., Neu, A., & Soltesz, I. (2007). Cell type-specific gating of perisomatic inhibition by cholecystokinin. NAT NEUROSCI, 10(9), 1128-30. https://doi.org/10.1038/nn1952

Vancouver

Földy C, Lee SY, Szabadics J, Neu A, Soltesz I. Cell type-specific gating of perisomatic inhibition by cholecystokinin. NAT NEUROSCI. 2007 Sep 1;10(9):1128-30. https://doi.org/10.1038/nn1952

Bibtex

@article{494d801280b7465c92081b7cb027ab81,
title = "Cell type-specific gating of perisomatic inhibition by cholecystokinin",
abstract = "Parvalbumin- and cholecystokinin (CCK)-expressing basket cells provide two parallel, functionally distinct sources of perisomatic inhibition to postsynaptic cells. We show that exogenously applied CCK enhances the output from rat parvalbumin-expressing basket cells, while concurrently suppressing GABA release from CCK-expressing neurons through retrograde endocannabinoid action. These results indicate that CCK may act as a molecular switch that determines the source of perisomatic inhibition for hippocampal principal cells.",
keywords = "Animals, Benzodiazepines, Calcium Channel Blockers, Cholecystokinin, Dose-Response Relationship, Drug, Drug Interactions, Hippocampus, Hormone Antagonists, Ion Channel Gating, Membrane Potentials, Neural Inhibition, Neurons, Parvalbumins, Patch-Clamp Techniques, Rats, gamma-Aminobutyric Acid",
author = "Csaba F{\"o}ldy and Lee, {Soo Yeun} and J{\'a}nos Szabadics and Axel Neu and Ivan Soltesz",
year = "2007",
month = sep,
day = "1",
doi = "10.1038/nn1952",
language = "English",
volume = "10",
pages = "1128--30",
journal = "NAT NEUROSCI",
issn = "1097-6256",
publisher = "NATURE PUBLISHING GROUP",
number = "9",

}

RIS

TY - JOUR

T1 - Cell type-specific gating of perisomatic inhibition by cholecystokinin

AU - Földy, Csaba

AU - Lee, Soo Yeun

AU - Szabadics, János

AU - Neu, Axel

AU - Soltesz, Ivan

PY - 2007/9/1

Y1 - 2007/9/1

N2 - Parvalbumin- and cholecystokinin (CCK)-expressing basket cells provide two parallel, functionally distinct sources of perisomatic inhibition to postsynaptic cells. We show that exogenously applied CCK enhances the output from rat parvalbumin-expressing basket cells, while concurrently suppressing GABA release from CCK-expressing neurons through retrograde endocannabinoid action. These results indicate that CCK may act as a molecular switch that determines the source of perisomatic inhibition for hippocampal principal cells.

AB - Parvalbumin- and cholecystokinin (CCK)-expressing basket cells provide two parallel, functionally distinct sources of perisomatic inhibition to postsynaptic cells. We show that exogenously applied CCK enhances the output from rat parvalbumin-expressing basket cells, while concurrently suppressing GABA release from CCK-expressing neurons through retrograde endocannabinoid action. These results indicate that CCK may act as a molecular switch that determines the source of perisomatic inhibition for hippocampal principal cells.

KW - Animals

KW - Benzodiazepines

KW - Calcium Channel Blockers

KW - Cholecystokinin

KW - Dose-Response Relationship, Drug

KW - Drug Interactions

KW - Hippocampus

KW - Hormone Antagonists

KW - Ion Channel Gating

KW - Membrane Potentials

KW - Neural Inhibition

KW - Neurons

KW - Parvalbumins

KW - Patch-Clamp Techniques

KW - Rats

KW - gamma-Aminobutyric Acid

U2 - 10.1038/nn1952

DO - 10.1038/nn1952

M3 - SCORING: Journal article

C2 - 17676058

VL - 10

SP - 1128

EP - 1130

JO - NAT NEUROSCI

JF - NAT NEUROSCI

SN - 1097-6256

IS - 9

ER -