CD8-mediated inflammatory central nervous system disorders.

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CD8-mediated inflammatory central nervous system disorders. / Willing, Anne; Friese, Manuel A.

In: CURR OPIN NEUROL, Vol. 25, No. 3, 3, 2012, p. 316-321.

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@article{075c3fbd22bd4003927e093b6461c0da,
title = "CD8-mediated inflammatory central nervous system disorders.",
abstract = "In central nervous system (CNS) autoimmune disorders, CD8+ T cells have been reported to exert cytotoxic as well as regulatory functions. In virus-induced (meningo) encephalitis, they are essential for viral clearance, but can also cause severe immunopathology. This review aims to summarize the multifaceted roles CD8+ T cells can play in inflammatory CNS disorders.",
keywords = "Humans, Cell Movement, Cell Differentiation, Autoimmune Diseases of the Nervous System/*immunology, CD8-Positive T-Lymphocytes/*physiology, Central Nervous System Diseases/complications/*immunology/pathology/virology, Humans, Cell Movement, Cell Differentiation, Autoimmune Diseases of the Nervous System/*immunology, CD8-Positive T-Lymphocytes/*physiology, Central Nervous System Diseases/complications/*immunology/pathology/virology",
author = "Anne Willing and Friese, {Manuel A.}",
year = "2012",
language = "English",
volume = "25",
pages = "316--321",
journal = "CURR OPIN NEUROL",
issn = "1350-7540",
publisher = "Lippincott Williams and Wilkins",
number = "3",

}

RIS

TY - JOUR

T1 - CD8-mediated inflammatory central nervous system disorders.

AU - Willing, Anne

AU - Friese, Manuel A.

PY - 2012

Y1 - 2012

N2 - In central nervous system (CNS) autoimmune disorders, CD8+ T cells have been reported to exert cytotoxic as well as regulatory functions. In virus-induced (meningo) encephalitis, they are essential for viral clearance, but can also cause severe immunopathology. This review aims to summarize the multifaceted roles CD8+ T cells can play in inflammatory CNS disorders.

AB - In central nervous system (CNS) autoimmune disorders, CD8+ T cells have been reported to exert cytotoxic as well as regulatory functions. In virus-induced (meningo) encephalitis, they are essential for viral clearance, but can also cause severe immunopathology. This review aims to summarize the multifaceted roles CD8+ T cells can play in inflammatory CNS disorders.

KW - Humans

KW - Cell Movement

KW - Cell Differentiation

KW - Autoimmune Diseases of the Nervous System/immunology

KW - CD8-Positive T-Lymphocytes/physiology

KW - Central Nervous System Diseases/complications/immunology/pathology/virology

KW - Humans

KW - Cell Movement

KW - Cell Differentiation

KW - Autoimmune Diseases of the Nervous System/immunology

KW - CD8-Positive T-Lymphocytes/physiology

KW - Central Nervous System Diseases/complications/immunology/pathology/virology

M3 - SCORING: Journal article

VL - 25

SP - 316

EP - 321

JO - CURR OPIN NEUROL

JF - CURR OPIN NEUROL

SN - 1350-7540

IS - 3

M1 - 3

ER -