CD8-mediated inflammatory central nervous system disorders.
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CD8-mediated inflammatory central nervous system disorders. / Willing, Anne; Friese, Manuel A.
In: CURR OPIN NEUROL, Vol. 25, No. 3, 3, 2012, p. 316-321.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
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TY - JOUR
T1 - CD8-mediated inflammatory central nervous system disorders.
AU - Willing, Anne
AU - Friese, Manuel A.
PY - 2012
Y1 - 2012
N2 - In central nervous system (CNS) autoimmune disorders, CD8+ T cells have been reported to exert cytotoxic as well as regulatory functions. In virus-induced (meningo) encephalitis, they are essential for viral clearance, but can also cause severe immunopathology. This review aims to summarize the multifaceted roles CD8+ T cells can play in inflammatory CNS disorders.
AB - In central nervous system (CNS) autoimmune disorders, CD8+ T cells have been reported to exert cytotoxic as well as regulatory functions. In virus-induced (meningo) encephalitis, they are essential for viral clearance, but can also cause severe immunopathology. This review aims to summarize the multifaceted roles CD8+ T cells can play in inflammatory CNS disorders.
KW - Humans
KW - Cell Movement
KW - Cell Differentiation
KW - Autoimmune Diseases of the Nervous System/immunology
KW - CD8-Positive T-Lymphocytes/physiology
KW - Central Nervous System Diseases/complications/immunology/pathology/virology
KW - Humans
KW - Cell Movement
KW - Cell Differentiation
KW - Autoimmune Diseases of the Nervous System/immunology
KW - CD8-Positive T-Lymphocytes/physiology
KW - Central Nervous System Diseases/complications/immunology/pathology/virology
M3 - SCORING: Journal article
VL - 25
SP - 316
EP - 321
JO - CURR OPIN NEUROL
JF - CURR OPIN NEUROL
SN - 1350-7540
IS - 3
M1 - 3
ER -