Case Report: Early detection of lung carcinoid in an asymptomatic individual by blood-test initiated PET-CT imaging

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Case Report: Early detection of lung carcinoid in an asymptomatic individual by blood-test initiated PET-CT imaging. / Burg, Simon; Smeets, Ralf; Gosau, Martin; Failing, Katja; Grust, Audrey Laure Céline.

In: FRONT ONCOL, Vol. 13, 2023, p. 1177237.

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@article{f77b76b063c04987a7eaa96e7c7b9ee1,
title = "Case Report: Early detection of lung carcinoid in an asymptomatic individual by blood-test initiated PET-CT imaging",
abstract = "We present the case of a 53-year-old woman who was diagnosed with early-stage lung cancer by targeted cancer screening consisting of an immunological biopsy-based blood test followed by radiological imaging. The PanTum Detect blood test detects the biomarkers Apo10/DNaseX and Transketolase-like 1 (TKTL1) in circulating macrophage-like cells from peripheral blood samples to identify asymptomatic individuals with a high risk for malignancy. The elevated blood test values initiated an 18F-FDG PET/CT visualization for further clarification. In this case, imaging indicated a lung carcinoma in the right upper lobe. A biopsy confirmed the presence of a lung carcinoma, which was removed surgically. Histologic examination revealed a typical I A2 carcinoid, which was completely removed, making further therapy obsolete.",
author = "Simon Burg and Ralf Smeets and Martin Gosau and Katja Failing and Grust, {Audrey Laure C{\'e}line}",
note = "Copyright {\textcopyright} 2023 Burg, Smeets, Gosau, Failing and Grust.",
year = "2023",
doi = "10.3389/fonc.2023.1177237",
language = "English",
volume = "13",
pages = "1177237",
journal = "FRONT ONCOL",
issn = "2234-943X",
publisher = "Frontiers Media S. A.",

}

RIS

TY - JOUR

T1 - Case Report: Early detection of lung carcinoid in an asymptomatic individual by blood-test initiated PET-CT imaging

AU - Burg, Simon

AU - Smeets, Ralf

AU - Gosau, Martin

AU - Failing, Katja

AU - Grust, Audrey Laure Céline

N1 - Copyright © 2023 Burg, Smeets, Gosau, Failing and Grust.

PY - 2023

Y1 - 2023

N2 - We present the case of a 53-year-old woman who was diagnosed with early-stage lung cancer by targeted cancer screening consisting of an immunological biopsy-based blood test followed by radiological imaging. The PanTum Detect blood test detects the biomarkers Apo10/DNaseX and Transketolase-like 1 (TKTL1) in circulating macrophage-like cells from peripheral blood samples to identify asymptomatic individuals with a high risk for malignancy. The elevated blood test values initiated an 18F-FDG PET/CT visualization for further clarification. In this case, imaging indicated a lung carcinoma in the right upper lobe. A biopsy confirmed the presence of a lung carcinoma, which was removed surgically. Histologic examination revealed a typical I A2 carcinoid, which was completely removed, making further therapy obsolete.

AB - We present the case of a 53-year-old woman who was diagnosed with early-stage lung cancer by targeted cancer screening consisting of an immunological biopsy-based blood test followed by radiological imaging. The PanTum Detect blood test detects the biomarkers Apo10/DNaseX and Transketolase-like 1 (TKTL1) in circulating macrophage-like cells from peripheral blood samples to identify asymptomatic individuals with a high risk for malignancy. The elevated blood test values initiated an 18F-FDG PET/CT visualization for further clarification. In this case, imaging indicated a lung carcinoma in the right upper lobe. A biopsy confirmed the presence of a lung carcinoma, which was removed surgically. Histologic examination revealed a typical I A2 carcinoid, which was completely removed, making further therapy obsolete.

U2 - 10.3389/fonc.2023.1177237

DO - 10.3389/fonc.2023.1177237

M3 - Case report

C2 - 37346076

VL - 13

SP - 1177237

JO - FRONT ONCOL

JF - FRONT ONCOL

SN - 2234-943X

ER -