Carbonic anhydrase IX in tumor tissue and sera of patients with primary cervical cancer.

Linn Wölber; Kerstin Kress; Jan Felix Kersten; Matthias Choschzick; Ergün Kilic; Uwe Herwig; Christoph Lindner; Jörg Schwarz; Fritz Jänicke; Sven Mahner; Karin Milde-Langosch; Volkmar Müller; Maike Henningsen

doi:10.1186/1471-2407-11-12

Carbonic anhydrase IX in tumor tissue and sera of patients with primary cervical cancer.

Linn Wölber
Kerstin Kress
Jan Felix Kersten
Matthias Choschzick
Ergün Kilic
Uwe Herwig
Christoph Lindner
Jörg Schwarz
Fritz Jänicke
Sven Mahner
Karin Milde-Langosch
Volkmar Müller
Maike Henningsen

Related Research units

Department of Gynecology
Institute of Medical Biometry and Epidemiology
Institute of Pathology

Abstract

Carbonic anhydrase IX (CAIX) is a membranous expressed metalloenzyme involved in pH homeostasis and cell adhesion. The protein is overexpressed in a variety of tumors and potentially associated with negative outcome. This study was designed to investigate the prognostic role of CAIX in serum and tumor tissue of patients with primary cervical cancer.

Bibliographical data

Original language	German
ISSN	1471-2407
DOIs	https://doi.org/10.1186/1471-2407-11-12
Publication status	Published - 2011

pubmed	21223596