Carbon monoxide inhalation reduces pulmonary inflammatory response during cardiopulmonary bypass in pigs.

  • Ulrich Goebel
  • Matthias Siepe
  • Anne Mecklenburg
  • Phillip Stein
  • Martin Roesslein
  • Christian I Schwer
  • Rene Schmidt
  • Torsten Doenst
  • Klaus K Geiger
  • Heike L Pahl
  • Christian Schlensak
  • Torsten Loop

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Abstract

Cardiopulmonary bypass (CPB) is associated with pulmonary inflammation and dysfunction. This may lead to acute lung injury and acute respiratory distress syndrome with increased morbidity and mortality. The authors hypothesized that inhaled carbon monoxide before initiation of CPB would reduce inflammatory response in the lungs.

Bibliographical data

Original languageGerman
Article number6
ISSN0003-3022
Publication statusPublished - 2008
pubmed 18497603