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Carbon fiber-reinforced PEEK versus titanium implants - an in vitro comparison of susceptibility artifacts in CT and MR imaging

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Carbon fiber-reinforced PEEK versus titanium implants - an in vitro comparison of susceptibility artifacts in CT and MR imaging. / Krätzig, Theresa; Mende, Klaus C; Mohme, Malte; Kniep, Helge; Dreimann, Marc; Stangenberg, Martin; Westphal, Manfred; Gauer, Tobias; Eicker, Sven O.

In: NEUROSURG REV, Vol. 44, No. 4, 08.2021, p. 2163-2170.

Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

Harvard

Krätzig, T, Mende, KC, Mohme, M, Kniep, H, Dreimann, M, Stangenberg, M, Westphal, M, Gauer, T & Eicker, SO 2021, 'Carbon fiber-reinforced PEEK versus titanium implants - an in vitro comparison of susceptibility artifacts in CT and MR imaging', NEUROSURG REV, vol. 44, no. 4, pp. 2163-2170. https://doi.org/10.1007/s10143-020-01384-2

APA

Krätzig, T., Mende, K. C., Mohme, M., Kniep, H., Dreimann, M., Stangenberg, M., Westphal, M., Gauer, T., & Eicker, S. O. (2021). Carbon fiber-reinforced PEEK versus titanium implants - an in vitro comparison of susceptibility artifacts in CT and MR imaging. NEUROSURG REV, 44(4), 2163-2170. https://doi.org/10.1007/s10143-020-01384-2

Vancouver

Krätzig T, Mende KC, Mohme M, Kniep H, Dreimann M, Stangenberg M et al. Carbon fiber-reinforced PEEK versus titanium implants - an in vitro comparison of susceptibility artifacts in CT and MR imaging. NEUROSURG REV. 2021 Aug;44(4):2163-2170. https://doi.org/10.1007/s10143-020-01384-2

Bibtex

@article{1c26720773a8444b9299efe7f241179a,
title = "Carbon fiber-reinforced PEEK versus titanium implants - an in vitro comparison of susceptibility artifacts in CT and MR imaging",
abstract = "Artifacts in computed tomography (CT) and magnetic resonance imaging (MRI) due to titanium implants in spine surgery are known to cause difficulties in follow-up imaging, radiation planning, and precise dose delivery in patients with spinal tumors. Carbon fiber-reinforced polyetheretherketon (CFRP) implants aim to reduce these artifacts. Our aim was to analyze susceptibility artifacts of these implants using a standardized in vitro model. Titanium and CFRP screw-rod phantoms were embedded in 3% agarose gel. Phantoms were scanned with Siemens Somatom AS Open and 3.0-T Siemens Skyra scanners. Regions of interest (ROIs) were plotted and analyzed for CT and MRI at clinically relevant localizations. CT voxel-based imaging analysis showed a significant difference of artifact intensity and central overlay between titanium and CFRP phantoms. For the virtual regions of the spinal canal, titanium implants (ti) presented - 30.7 HU vs. 33.4 HU mean for CFRP (p < 0.001), at the posterior margin of the vertebral body 68.9 HU (ti) vs. 59.8 HU (CFRP) (p < 0.001) and at the anterior part of the vertebral body 201.2 HU (ti) vs. 70.4 HU (CFRP) (p < 0.001), respectively. MRI data was only visually interpreted due to the low sample size and lack of an objective measuring system as Hounsfield units in CT. CT imaging of the phantom with typical implant configuration for thoracic stabilization could demonstrate a significant artifact reduction in CFRP implants compared with titanium implants for evaluation of index structures. Radiolucency with less artifacts provides a better interpretation of follow-up imaging, radiation planning, and more precise dose delivery.",
author = "Theresa Kr{\"a}tzig and Mende, {Klaus C} and Malte Mohme and Helge Kniep and Marc Dreimann and Martin Stangenberg and Manfred Westphal and Tobias Gauer and Eicker, {Sven O}",
year = "2021",
month = aug,
doi = "10.1007/s10143-020-01384-2",
language = "English",
volume = "44",
pages = "2163--2170",
journal = "NEUROSURG REV",
issn = "0344-5607",
publisher = "Springer",
number = "4",

}

RIS

TY - JOUR

T1 - Carbon fiber-reinforced PEEK versus titanium implants - an in vitro comparison of susceptibility artifacts in CT and MR imaging

AU - Krätzig, Theresa

AU - Mende, Klaus C

AU - Mohme, Malte

AU - Kniep, Helge

AU - Dreimann, Marc

AU - Stangenberg, Martin

AU - Westphal, Manfred

AU - Gauer, Tobias

AU - Eicker, Sven O

PY - 2021/8

Y1 - 2021/8

N2 - Artifacts in computed tomography (CT) and magnetic resonance imaging (MRI) due to titanium implants in spine surgery are known to cause difficulties in follow-up imaging, radiation planning, and precise dose delivery in patients with spinal tumors. Carbon fiber-reinforced polyetheretherketon (CFRP) implants aim to reduce these artifacts. Our aim was to analyze susceptibility artifacts of these implants using a standardized in vitro model. Titanium and CFRP screw-rod phantoms were embedded in 3% agarose gel. Phantoms were scanned with Siemens Somatom AS Open and 3.0-T Siemens Skyra scanners. Regions of interest (ROIs) were plotted and analyzed for CT and MRI at clinically relevant localizations. CT voxel-based imaging analysis showed a significant difference of artifact intensity and central overlay between titanium and CFRP phantoms. For the virtual regions of the spinal canal, titanium implants (ti) presented - 30.7 HU vs. 33.4 HU mean for CFRP (p < 0.001), at the posterior margin of the vertebral body 68.9 HU (ti) vs. 59.8 HU (CFRP) (p < 0.001) and at the anterior part of the vertebral body 201.2 HU (ti) vs. 70.4 HU (CFRP) (p < 0.001), respectively. MRI data was only visually interpreted due to the low sample size and lack of an objective measuring system as Hounsfield units in CT. CT imaging of the phantom with typical implant configuration for thoracic stabilization could demonstrate a significant artifact reduction in CFRP implants compared with titanium implants for evaluation of index structures. Radiolucency with less artifacts provides a better interpretation of follow-up imaging, radiation planning, and more precise dose delivery.

AB - Artifacts in computed tomography (CT) and magnetic resonance imaging (MRI) due to titanium implants in spine surgery are known to cause difficulties in follow-up imaging, radiation planning, and precise dose delivery in patients with spinal tumors. Carbon fiber-reinforced polyetheretherketon (CFRP) implants aim to reduce these artifacts. Our aim was to analyze susceptibility artifacts of these implants using a standardized in vitro model. Titanium and CFRP screw-rod phantoms were embedded in 3% agarose gel. Phantoms were scanned with Siemens Somatom AS Open and 3.0-T Siemens Skyra scanners. Regions of interest (ROIs) were plotted and analyzed for CT and MRI at clinically relevant localizations. CT voxel-based imaging analysis showed a significant difference of artifact intensity and central overlay between titanium and CFRP phantoms. For the virtual regions of the spinal canal, titanium implants (ti) presented - 30.7 HU vs. 33.4 HU mean for CFRP (p < 0.001), at the posterior margin of the vertebral body 68.9 HU (ti) vs. 59.8 HU (CFRP) (p < 0.001) and at the anterior part of the vertebral body 201.2 HU (ti) vs. 70.4 HU (CFRP) (p < 0.001), respectively. MRI data was only visually interpreted due to the low sample size and lack of an objective measuring system as Hounsfield units in CT. CT imaging of the phantom with typical implant configuration for thoracic stabilization could demonstrate a significant artifact reduction in CFRP implants compared with titanium implants for evaluation of index structures. Radiolucency with less artifacts provides a better interpretation of follow-up imaging, radiation planning, and more precise dose delivery.

U2 - 10.1007/s10143-020-01384-2

DO - 10.1007/s10143-020-01384-2

M3 - SCORING: Journal article

C2 - 32930911

VL - 44

SP - 2163

EP - 2170

JO - NEUROSURG REV

JF - NEUROSURG REV

SN - 0344-5607

IS - 4

ER -