Candida mediastinitis with aortic rupture after congenital heart surgery
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Candida mediastinitis with aortic rupture after congenital heart surgery. / Knirsch, Walter; Cavigelli-Brunner, Anna; Dodge-Khatami, Ali; Mund, Michael T.; Büchel, Emanuela R.Valsangiacomo.
In: INT J CARDIOL, Vol. 134, No. 2, 15.05.2009, p. e76-e78.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
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TY - JOUR
T1 - Candida mediastinitis with aortic rupture after congenital heart surgery
AU - Knirsch, Walter
AU - Cavigelli-Brunner, Anna
AU - Dodge-Khatami, Ali
AU - Mund, Michael T.
AU - Büchel, Emanuela R.Valsangiacomo
PY - 2009/5/15
Y1 - 2009/5/15
N2 - We describe the fatal course of a Candida albicans mediastinitis in a 4-year-old child after truncus arteriosus repair, leading to aortic rupture. The diagnosis was made by computer tomography and confirmed at exploratory sternotomy, with positive swab and blood cultures. After local surgical lavage, Amphotericin B therapy was started, but the child died due to aortic rupture 2 weeks later, despite negative blood cultures. The potential risk of aortic rupture with Candida mediastinitis after congenital heart repair exists, and combined aggressive surgical and medical treatment is essential. Guidelines for the diagnosis and therapy in pediatric patients with post-operative mycotic mediastinitis are required.
AB - We describe the fatal course of a Candida albicans mediastinitis in a 4-year-old child after truncus arteriosus repair, leading to aortic rupture. The diagnosis was made by computer tomography and confirmed at exploratory sternotomy, with positive swab and blood cultures. After local surgical lavage, Amphotericin B therapy was started, but the child died due to aortic rupture 2 weeks later, despite negative blood cultures. The potential risk of aortic rupture with Candida mediastinitis after congenital heart repair exists, and combined aggressive surgical and medical treatment is essential. Guidelines for the diagnosis and therapy in pediatric patients with post-operative mycotic mediastinitis are required.
KW - Aortic rupture
KW - Candida
KW - Congenital heart disease
KW - Mediastinitis
UR - http://www.scopus.com/inward/record.url?scp=64849109394&partnerID=8YFLogxK
U2 - 10.1016/j.ijcard.2007.12.094
DO - 10.1016/j.ijcard.2007.12.094
M3 - SCORING: Journal article
C2 - 18378335
AN - SCOPUS:64849109394
VL - 134
SP - e76-e78
JO - INT J CARDIOL
JF - INT J CARDIOL
SN - 0167-5273
IS - 2
ER -