Can homogeneous, lipomatous tumors be primarily resected without biopsy? A retrospective analysis of 240 tumors

TY - JOUR

T1 - Can homogeneous, lipomatous tumors be primarily resected without biopsy? A retrospective analysis of 240 tumors

AU - Ballhause, Tobias Malte

AU - Weiß, Sebastian

AU - Reiter, Alonja

AU - Frosch, Karl-Heinz

AU - Luebke, Andreas M.

AU - Bannas, Peter

AU - Schlickewei, Carsten

AU - Priemel, Matthias

PY - 2022/6/8

Y1 - 2022/6/8

N2 - BackgroundAccording to guidelines, every soft tissue tumor (STT) larger than 3 cm should be biopsied before definitive resection. Advances in magnetic resonance imaging (MRI) improve the possibility to give a provisional diagnosis of the tumor’s entity. Can lipomas and atypical lipomatous tumors (ALTs) of the extremities therefore be primarily marginally resected based on interpretation of MR images without a previous biopsy?.MethodsIn this retrospective, single-center study, 240 patients with the suspicion of a lipomatous tumor in MRI and surgical treatment in our institution between 2011 and 2020 were included. MR imaging was performed before surgery. All resected specimens underwent histopathological analysis.ResultsThe collective comprised 142 tumors that were suspected as lipoma or ALT by the radiologist and underwent primary marginal resection (PMR). One case had myxoid liposarcoma that was underestimated on MRI and needed radical follow-up resection. One-hundred forty-one patients were cured after PMR. Ninety-eight patients were biopsied initially and in 93 cases resected afterwards according to the necessary oncological margins.ConclusionIn our institution, PMR is performed if a lipoma or ALT is suspected on MR imaging. Our treatment method and the diagnostic algorithm are presented. Primary resection spares patients from one surgical procedure, but a slight risk for underestimation of the tumor remains.

AB - BackgroundAccording to guidelines, every soft tissue tumor (STT) larger than 3 cm should be biopsied before definitive resection. Advances in magnetic resonance imaging (MRI) improve the possibility to give a provisional diagnosis of the tumor’s entity. Can lipomas and atypical lipomatous tumors (ALTs) of the extremities therefore be primarily marginally resected based on interpretation of MR images without a previous biopsy?.MethodsIn this retrospective, single-center study, 240 patients with the suspicion of a lipomatous tumor in MRI and surgical treatment in our institution between 2011 and 2020 were included. MR imaging was performed before surgery. All resected specimens underwent histopathological analysis.ResultsThe collective comprised 142 tumors that were suspected as lipoma or ALT by the radiologist and underwent primary marginal resection (PMR). One case had myxoid liposarcoma that was underestimated on MRI and needed radical follow-up resection. One-hundred forty-one patients were cured after PMR. Ninety-eight patients were biopsied initially and in 93 cases resected afterwards according to the necessary oncological margins.ConclusionIn our institution, PMR is performed if a lipoma or ALT is suspected on MR imaging. Our treatment method and the diagnostic algorithm are presented. Primary resection spares patients from one surgical procedure, but a slight risk for underestimation of the tumor remains.

U2 - 10.1186/s12957-022-02665-4

DO - 10.1186/s12957-022-02665-4

M3 - SCORING: Journal article

VL - 20

SP - 184

JO - WORLD J SURG ONCOL

JF - WORLD J SURG ONCOL

SN - 1477-7819

IS - 1

M1 - 184

ER -