Calcifying epithelial odontogenic tumour of the maxilla: a case report with respect to immunohistochemical findings.
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Calcifying epithelial odontogenic tumour of the maxilla: a case report with respect to immunohistochemical findings. / Friedrich, Reinhard; Zustin, Jozef.
In: IN VIVO, Vol. 25, No. 2, 2, 2011, p. 259-264.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
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TY - JOUR
T1 - Calcifying epithelial odontogenic tumour of the maxilla: a case report with respect to immunohistochemical findings.
AU - Friedrich, Reinhard
AU - Zustin, Jozef
PY - 2011
Y1 - 2011
N2 - Calcifying epithelial odontogenic tumour (Pindborg tumour) is a rare benign neoplasm with a poorly understood histogenesis. This report describes a single case of a maxillary calcifying epithelial odontogenic tumour including immunohistochemical analysis. The vast majority of tumour cells were positive for CK5/6 and p63. Furthermore, basal cells also displayed moderate reaction for vimentin and strong membranous positivity for podoplanin. Interestingly, the tumour invaded the dental pulp of the partially disintegrated tooth root. While the tumour showed focal connection with the superficial gingival epithelium and revealed intercellular bridges, the findings of this case study seem to support the suggestion of an epithelial origin of a calcifying epithelial odontogenic tumour derived from the dental lamina.
AB - Calcifying epithelial odontogenic tumour (Pindborg tumour) is a rare benign neoplasm with a poorly understood histogenesis. This report describes a single case of a maxillary calcifying epithelial odontogenic tumour including immunohistochemical analysis. The vast majority of tumour cells were positive for CK5/6 and p63. Furthermore, basal cells also displayed moderate reaction for vimentin and strong membranous positivity for podoplanin. Interestingly, the tumour invaded the dental pulp of the partially disintegrated tooth root. While the tumour showed focal connection with the superficial gingival epithelium and revealed intercellular bridges, the findings of this case study seem to support the suggestion of an epithelial origin of a calcifying epithelial odontogenic tumour derived from the dental lamina.
KW - Humans
KW - Male
KW - Middle Aged
KW - Immunohistochemistry
KW - Tomography, X-Ray Computed
KW - Actins/analysis
KW - Keratin-5/analysis
KW - Keratin-6/analysis
KW - Maxilla/metabolism/pathology
KW - Muscle, Smooth/chemistry
KW - Odontogenic Tumors/diagnosis/metabolism
KW - Skin Neoplasms/diagnosis/metabolism
KW - Humans
KW - Male
KW - Middle Aged
KW - Immunohistochemistry
KW - Tomography, X-Ray Computed
KW - Actins/analysis
KW - Keratin-5/analysis
KW - Keratin-6/analysis
KW - Maxilla/metabolism/pathology
KW - Muscle, Smooth/chemistry
KW - Odontogenic Tumors/diagnosis/metabolism
KW - Skin Neoplasms/diagnosis/metabolism
M3 - SCORING: Journal article
C2 - 21471544
VL - 25
SP - 259
EP - 264
JO - IN VIVO
JF - IN VIVO
SN - 0258-851X
IS - 2
M1 - 2
ER -
