BSc2118 is a novel proteasome inhibitor with activity against multiple myeloma.

  • Jan Sterz
  • Christian Jakob
  • Ulrike Kuckelkorn
  • Ulrike Heider
  • Maren Mieth
  • Lorenz Kleeberg
  • Martin Kaiser
  • Peter-M Kloetzel
  • Orhan Sezer
  • Ivana von Metzler

Related Research units

Abstract

The ubiquitin-proteasome system emerged as a new therapeutic target in cancer treatment. The purpose of this study was to elucidate the effects of the novel proteasome inhibitor BSc2118 on t(4;14) positive and negative multiple myeloma (MM) cells and normal peripheral blood mononuclear cells (PBMNC).

Bibliographical data

Original languageGerman
Article number2
ISSN0902-4441
Publication statusPublished - 2010
pubmed 20374272