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Bonus-freeze: benefit or risk? Two-year outcome and procedural comparison of a "bonus-freeze" and "no bonus-freeze" protocol using the second-generation cryoballoon for pulmonary vein isolation

Standard

Bonus-freeze: benefit or risk? Two-year outcome and procedural comparison of a "bonus-freeze" and "no bonus-freeze" protocol using the second-generation cryoballoon for pulmonary vein isolation. / Heeger, Christian-H; Wissner, Erik; Wohlmuth, Peter; Mathew, Shibu; Hayashi, Kentaro; Sohns, Christian; Reißmann, Bruno; Lemes, Christine; Maurer, Tilman; Saguner, Ardan M; Santoro, Francesco; Riedl, Johannes; Ouyang, Feifan; Kuck, Karl-Heinz; Metzner, Andreas.

In: CLIN RES CARDIOL, Vol. 105, No. 9, 09.2016, p. 774-82.

Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

Harvard

Heeger, C-H, Wissner, E, Wohlmuth, P, Mathew, S, Hayashi, K, Sohns, C, Reißmann, B, Lemes, C, Maurer, T, Saguner, AM, Santoro, F, Riedl, J, Ouyang, F, Kuck, K-H & Metzner, A 2016, 'Bonus-freeze: benefit or risk? Two-year outcome and procedural comparison of a "bonus-freeze" and "no bonus-freeze" protocol using the second-generation cryoballoon for pulmonary vein isolation', CLIN RES CARDIOL, vol. 105, no. 9, pp. 774-82. https://doi.org/10.1007/s00392-016-0987-8

APA

Heeger, C-H., Wissner, E., Wohlmuth, P., Mathew, S., Hayashi, K., Sohns, C., Reißmann, B., Lemes, C., Maurer, T., Saguner, A. M., Santoro, F., Riedl, J., Ouyang, F., Kuck, K-H., & Metzner, A. (2016). Bonus-freeze: benefit or risk? Two-year outcome and procedural comparison of a "bonus-freeze" and "no bonus-freeze" protocol using the second-generation cryoballoon for pulmonary vein isolation. CLIN RES CARDIOL, 105(9), 774-82. https://doi.org/10.1007/s00392-016-0987-8

Vancouver

Heeger C-H, Wissner E, Wohlmuth P, Mathew S, Hayashi K, Sohns C et al. Bonus-freeze: benefit or risk? Two-year outcome and procedural comparison of a "bonus-freeze" and "no bonus-freeze" protocol using the second-generation cryoballoon for pulmonary vein isolation. CLIN RES CARDIOL. 2016 Sep;105(9):774-82. https://doi.org/10.1007/s00392-016-0987-8

Bibtex

@article{979da02752b44604b358623a1fcfa6aa,
title = "Bonus-freeze: benefit or risk? Two-year outcome and procedural comparison of a {"}bonus-freeze{"} and {"}no bonus-freeze{"} protocol using the second-generation cryoballoon for pulmonary vein isolation",
abstract = "BACKGROUND: Second-generation cryoballoon based pulmonary vein isolation has demonstrated encouraging acute and mid-term clinical outcome. Customarily, a bonus-freeze is applied after successful pulmonary vein isolation.OBJECTIVE: To compare the long-term clinical outcome and safety profile of a bonus-freeze and a no bonus-freeze protocol.METHODS: A total of 120 consecutive patients with paroxysmal [95/120 (79 %)] or persistent atrial fibrillation [25/120 (21 %)] underwent CB2-based PVI. Freeze-cycle duration was 240 s. In the first 60 patients a bonus-freeze was applied after successful PVI (group 1), while in the following 60 patients the bonus-freeze was omitted (group 2).RESULTS: Procedure and fluoroscopy times were significantly shorter in group 2 [113.8 ± 32 vs 138.2 ± 29 min (p = 0.03) and 19.2 ± 6 vs 24.3 ± 8 min (p = 0.02)]. No differences in procedural complications were found. During a mean follow-up of 849 ± 74 (group 1) and 848 ± 101 days (group 2, p = 0.13) 69 % of patients (group 1) and 67 % of patients (group 2) remained in stable sinus rhythm without any differences between the groups (p = 0.69).CONCLUSIONS: Freedom from atrial fibrillation after second-generation cryoballoon based pulmonary vein isolation and a follow-up of >2 years is comparable when applying a bonus- and a no bonus-freeze protocol, while procedure and fluoroscopy times are significantly shorter when omitting the bonus-freeze. No differences in periprocedural complications were identified.",
keywords = "Aged, Atrial Fibrillation/diagnostic imaging, Cardiac Catheters, Cryosurgery/adverse effects, Electrocardiography, Ambulatory, Equipment Design, Female, Fluoroscopy, Humans, Male, Middle Aged, Pulmonary Veins/diagnostic imaging, Radiation Dosage, Radiation Exposure, Radiography, Interventional/methods, Retrospective Studies, Risk Assessment, Risk Factors, Time Factors, Treatment Outcome",
author = "Christian-H Heeger and Erik Wissner and Peter Wohlmuth and Shibu Mathew and Kentaro Hayashi and Christian Sohns and Bruno Rei{\ss}mann and Christine Lemes and Tilman Maurer and Saguner, {Ardan M} and Francesco Santoro and Johannes Riedl and Feifan Ouyang and Karl-Heinz Kuck and Andreas Metzner",
year = "2016",
month = sep,
doi = "10.1007/s00392-016-0987-8",
language = "English",
volume = "105",
pages = "774--82",
journal = "CLIN RES CARDIOL",
issn = "1861-0684",
publisher = "D. Steinkopff-Verlag",
number = "9",

}

RIS

TY - JOUR

T1 - Bonus-freeze: benefit or risk? Two-year outcome and procedural comparison of a "bonus-freeze" and "no bonus-freeze" protocol using the second-generation cryoballoon for pulmonary vein isolation

AU - Heeger, Christian-H

AU - Wissner, Erik

AU - Wohlmuth, Peter

AU - Mathew, Shibu

AU - Hayashi, Kentaro

AU - Sohns, Christian

AU - Reißmann, Bruno

AU - Lemes, Christine

AU - Maurer, Tilman

AU - Saguner, Ardan M

AU - Santoro, Francesco

AU - Riedl, Johannes

AU - Ouyang, Feifan

AU - Kuck, Karl-Heinz

AU - Metzner, Andreas

PY - 2016/9

Y1 - 2016/9

N2 - BACKGROUND: Second-generation cryoballoon based pulmonary vein isolation has demonstrated encouraging acute and mid-term clinical outcome. Customarily, a bonus-freeze is applied after successful pulmonary vein isolation.OBJECTIVE: To compare the long-term clinical outcome and safety profile of a bonus-freeze and a no bonus-freeze protocol.METHODS: A total of 120 consecutive patients with paroxysmal [95/120 (79 %)] or persistent atrial fibrillation [25/120 (21 %)] underwent CB2-based PVI. Freeze-cycle duration was 240 s. In the first 60 patients a bonus-freeze was applied after successful PVI (group 1), while in the following 60 patients the bonus-freeze was omitted (group 2).RESULTS: Procedure and fluoroscopy times were significantly shorter in group 2 [113.8 ± 32 vs 138.2 ± 29 min (p = 0.03) and 19.2 ± 6 vs 24.3 ± 8 min (p = 0.02)]. No differences in procedural complications were found. During a mean follow-up of 849 ± 74 (group 1) and 848 ± 101 days (group 2, p = 0.13) 69 % of patients (group 1) and 67 % of patients (group 2) remained in stable sinus rhythm without any differences between the groups (p = 0.69).CONCLUSIONS: Freedom from atrial fibrillation after second-generation cryoballoon based pulmonary vein isolation and a follow-up of >2 years is comparable when applying a bonus- and a no bonus-freeze protocol, while procedure and fluoroscopy times are significantly shorter when omitting the bonus-freeze. No differences in periprocedural complications were identified.

AB - BACKGROUND: Second-generation cryoballoon based pulmonary vein isolation has demonstrated encouraging acute and mid-term clinical outcome. Customarily, a bonus-freeze is applied after successful pulmonary vein isolation.OBJECTIVE: To compare the long-term clinical outcome and safety profile of a bonus-freeze and a no bonus-freeze protocol.METHODS: A total of 120 consecutive patients with paroxysmal [95/120 (79 %)] or persistent atrial fibrillation [25/120 (21 %)] underwent CB2-based PVI. Freeze-cycle duration was 240 s. In the first 60 patients a bonus-freeze was applied after successful PVI (group 1), while in the following 60 patients the bonus-freeze was omitted (group 2).RESULTS: Procedure and fluoroscopy times were significantly shorter in group 2 [113.8 ± 32 vs 138.2 ± 29 min (p = 0.03) and 19.2 ± 6 vs 24.3 ± 8 min (p = 0.02)]. No differences in procedural complications were found. During a mean follow-up of 849 ± 74 (group 1) and 848 ± 101 days (group 2, p = 0.13) 69 % of patients (group 1) and 67 % of patients (group 2) remained in stable sinus rhythm without any differences between the groups (p = 0.69).CONCLUSIONS: Freedom from atrial fibrillation after second-generation cryoballoon based pulmonary vein isolation and a follow-up of >2 years is comparable when applying a bonus- and a no bonus-freeze protocol, while procedure and fluoroscopy times are significantly shorter when omitting the bonus-freeze. No differences in periprocedural complications were identified.

KW - Aged

KW - Atrial Fibrillation/diagnostic imaging

KW - Cardiac Catheters

KW - Cryosurgery/adverse effects

KW - Electrocardiography, Ambulatory

KW - Equipment Design

KW - Female

KW - Fluoroscopy

KW - Humans

KW - Male

KW - Middle Aged

KW - Pulmonary Veins/diagnostic imaging

KW - Radiation Dosage

KW - Radiation Exposure

KW - Radiography, Interventional/methods

KW - Retrospective Studies

KW - Risk Assessment

KW - Risk Factors

KW - Time Factors

KW - Treatment Outcome

U2 - 10.1007/s00392-016-0987-8

DO - 10.1007/s00392-016-0987-8

M3 - SCORING: Journal article

C2 - 27085722

VL - 105

SP - 774

EP - 782

JO - CLIN RES CARDIOL

JF - CLIN RES CARDIOL

SN - 1861-0684

IS - 9

ER -