Blutdruckmessung in der NAKO – methodische Unterschiede, Blutdruckverteilung und Bekanntheit der Hypertonie im Vergleich zu anderen bevölkerungsbezogenen Studien in Deutschland

TY - JOUR

T1 - Blutdruckmessung in der NAKO – methodische Unterschiede, Blutdruckverteilung und Bekanntheit der Hypertonie im Vergleich zu anderen bevölkerungsbezogenen Studien in Deutschland

AU - Schikowski, Tamara

AU - Wigmann, Claudia

AU - Fuks, Kateryna B

AU - Schipf, Sabine

AU - Heier, Margit

AU - Neuhauser, Hannelore

AU - Sarganas, Giselle

AU - Ahrens, Wolfgang

AU - Becher, Heiko

AU - Berger, Klaus

AU - Brenner, Hermann

AU - Castell, Stefanie

AU - Damms-Machado, Antje

AU - Dörr, Marcus

AU - Ebert, Nina

AU - Efremov, Ljupcho

AU - Emmel, Carina

AU - Felix, Stephan B

AU - Fischer, Beate

AU - Franzke, Claus-Werner

AU - Gastell, Sylvia

AU - Günther, Kathrin

AU - Haerting, Johannes

AU - Ittermann, Till

AU - Jaeschke, Lina

AU - Jagodzinski, Annika

AU - Jöckel, Karl-Heinz

AU - Kaaks, Rudolphe

AU - Kalinowski, Sonja

AU - Keil, Thomas

AU - Kemmling, Yvonne

AU - Kluttig, Alexander

AU - Krist, Lilian

AU - Kuss, Oliver

AU - Legath, Nicole

AU - Leitzmann, Michael

AU - Lieb, Wolfgang

AU - Löffler, Markus

AU - Meinke-Franze, Claudia

AU - Michels, Karin B

AU - Mikolajczyk, Rafael

AU - Moebus, Susanne

AU - Nuding, Sebastian

AU - Peters, Annette

AU - Pischon, Tobias

AU - Rückert-Eheberg, Ina-Maria

AU - Schöttker, Ben

AU - Schmidt, Börge

AU - Schmidt, Carsten Oliver

AU - Schulze, Matthias B

AU - Stang, Andreas

AU - Thiele, Inke

AU - Thierry, Sigrid

AU - Thorand, Barbara

AU - Völzke, Henry

AU - Waniek, Sabina

AU - Werdan, Karl

AU - Wirkner, Kerstin

AU - Greiser, Karin Halina

PY - 2020/4

Y1 - 2020/4

N2 - BACKGROUND: Arterial hypertension is animportant risk factor for cardiovascular diseases. Epidemiological studies typically perform three consecutive blood pressure measurements. The first measurement is discarded in subsequent analyses, as this value may be strongly affected by previous activities. Due to time constraints the German National Cohort (GNC NAKO) performed only two blood pressure measurements. OBJECTIVES: The present analysis examined the possible effects of methodological differences in blood pressure measurement by comparing the first 101,816 GNC participants (two blood pressure measurements) with those of five German population-based studies (three measurements). MATERIALS AND METHODS: Blood pressure data from participants aged 20 to 79 years from the GNC, the German Health Interview and Examination Survey for Adults by the Robert Koch Institute (DEGS1), and four regional population-based cohort studies (CARLA, HNR, KORA, SHIP) were used to calculate age- and sex-specific mean blood pressure values and hypertension frequencies based on the second blood pressure measurement, the arithmetic mean of the first and second value and of the second and third (the latter not available in the GNC). RESULTS: The mean blood pressure values of the two most recent studies (GNC, DEGS1) were very similar and lower than in the other studies. The difference of the second measurement and the mean of second and third measurement was small (maximum mean difference: 1.5mm Hg systolic blood pressure), but leads to higher estimated hypertension frequencies. CONCLUSIONS: The current results show that using the second blood pressure measurement should be recommended for scientific analyses of GNC data.

AB - BACKGROUND: Arterial hypertension is animportant risk factor for cardiovascular diseases. Epidemiological studies typically perform three consecutive blood pressure measurements. The first measurement is discarded in subsequent analyses, as this value may be strongly affected by previous activities. Due to time constraints the German National Cohort (GNC NAKO) performed only two blood pressure measurements. OBJECTIVES: The present analysis examined the possible effects of methodological differences in blood pressure measurement by comparing the first 101,816 GNC participants (two blood pressure measurements) with those of five German population-based studies (three measurements). MATERIALS AND METHODS: Blood pressure data from participants aged 20 to 79 years from the GNC, the German Health Interview and Examination Survey for Adults by the Robert Koch Institute (DEGS1), and four regional population-based cohort studies (CARLA, HNR, KORA, SHIP) were used to calculate age- and sex-specific mean blood pressure values and hypertension frequencies based on the second blood pressure measurement, the arithmetic mean of the first and second value and of the second and third (the latter not available in the GNC). RESULTS: The mean blood pressure values of the two most recent studies (GNC, DEGS1) were very similar and lower than in the other studies. The difference of the second measurement and the mean of second and third measurement was small (maximum mean difference: 1.5mm Hg systolic blood pressure), but leads to higher estimated hypertension frequencies. CONCLUSIONS: The current results show that using the second blood pressure measurement should be recommended for scientific analyses of GNC data.

KW - Blood Pressure

KW - Cohort Studies

KW - Germany

KW - Humans

KW - Hypertension

KW - Population Surveillance

U2 - 10.1007/s00103-020-03109-8

DO - 10.1007/s00103-020-03109-8

M3 - SCORING: Zeitschriftenaufsatz

C2 - 32170398

VL - 63

SP - 452

EP - 464

JO - BUNDESGESUNDHEITSBLA

JF - BUNDESGESUNDHEITSBLA

SN - 1436-9990

IS - 4

ER -